# Med-GRIM: Enhanced Zero-Shot Medical VQA using prompt-embedded Multimodal Graph RAG

arXiv: https://arxiv.org/abs/2508.06496 · HTML: https://mlsanity.com/paper/2508.06496/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Placed in Medical vision-language models, one of 16 directions in Multimodal LLMs / vision-language models.
- Builds on 31 of its 43 references that are in the map.
- First posted on arXiv 20 Jul 2025.

## Placed in

- Multimodal LLMs / vision-language models / [Medical vision-language models](https://mlsanity.com/mllm/medical-vision-language-models/)

## Builds on (most cited first, 30 of 31)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [Microsoft COCO: Common Objects in Context](https://mlsanity.com/paper/1405.0312/) (2014)
- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [Visual Instruction Tuning](https://mlsanity.com/paper/2304.08485/) (2023)
- [BLIP-2: Bootstrapping Language-Image Pre-training with Frozen Image Encoders and Large Language Models](https://mlsanity.com/paper/2301.12597/) (2023)
- [Flamingo: a Visual Language Model for Few-Shot Learning](https://mlsanity.com/paper/2204.14198/) (2022)
- [BLIP: Bootstrapping Language-Image Pre-training for Unified Vision-Language Understanding and Generation](https://mlsanity.com/paper/2201.12086/) (2022)
- [MiniGPT-4: Enhancing Vision-Language Understanding with Advanced Large Language Models](https://mlsanity.com/paper/2304.10592/) (2023)
- [VQA: Visual Question Answering](https://mlsanity.com/paper/1505.00468/) (2015)
- [Bottom-Up and Top-Down Attention for Image Captioning and Visual Question Answering](https://mlsanity.com/paper/1707.07998/) (2017)
- [LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day](https://mlsanity.com/paper/2306.00890/) (2023)
- [ImageBind: One Embedding Space To Bind Them All](https://mlsanity.com/paper/2305.05665/) (2023)
- [Multimodal Few-Shot Learning with Frozen Language Models](https://mlsanity.com/paper/2106.13884/) (2021)
- [BiomedCLIP: a multimodal biomedical foundation model pretrained from fifteen million scientific image-text pairs](https://mlsanity.com/paper/2303.00915/) (2023)
- [Med-Flamingo: a Multimodal Medical Few-shot Learner](https://mlsanity.com/paper/2307.15189/) (2023)
- [QA-GNN: Reasoning with Language Models and Knowledge Graphs for Question Answering](https://mlsanity.com/paper/2104.06378/) (2021)
- [MedAlpaca -- An Open-Source Collection of Medical Conversational AI Models and Training Data](https://mlsanity.com/paper/2304.08247/) (2023)
- [BiomedGPT: A Generalist Vision-Language Foundation Model for Diverse Biomedical Tasks](https://mlsanity.com/paper/2305.17100/) (2023)
- [VisualGPT: Data-efficient Adaptation of Pretrained Language Models for Image Captioning](https://mlsanity.com/paper/2102.10407/) (2021)
- [BLIVA: A Simple Multimodal LLM for Better Handling of Text-Rich Visual Questions](https://mlsanity.com/paper/2308.09936/) (2023)
- [Multimodal Contrastive Training for Visual Representation Learning](https://mlsanity.com/paper/2104.12836/) (2021)
- [Medical Graph RAG: Towards Safe Medical Large Language Model via Graph Retrieval-Augmented Generation](https://mlsanity.com/paper/2408.04187/) (2024)
- [MMed-RAG: Versatile Multimodal RAG System for Medical Vision Language Models](https://mlsanity.com/paper/2410.13085/) (2024)
- [Multimodal Representation Learning by Alternating Unimodal Adaptation](https://mlsanity.com/paper/2311.10707/) (2023)
- [CrossCLR: Cross-modal Contrastive Learning For Multi-modal Video Representations](https://mlsanity.com/paper/2109.14910/) (2021)
- [Overcoming Data Limitation in Medical Visual Question Answering](https://mlsanity.com/paper/1909.11867/) (2019)
- [RULE: Reliable Multimodal RAG for Factuality in Medical Vision Language Models](https://mlsanity.com/paper/2407.05131/) (2024)
- [RAMM: Retrieval-augmented Biomedical Visual Question Answering with Multi-modal Pre-training](https://mlsanity.com/paper/2303.00534/) (2023)
- [Veagle: Advancements in Multimodal Representation Learning](https://mlsanity.com/paper/2403.08773/) (2024)

## Built on by (most cited first, 1 of 1)

- [The Path to Self-Evolving Clinical Systems: Scaling Medical Agents from Assistance to Autonomy](https://mlsanity.com/paper/2607.11175/) (2026)

## Abstract (arXiv)

An ensemble of trained multimodal encoders and vision-language models (VLMs) has become a standard approach for visual question answering (VQA) tasks. However, such models often fail to produce responses with the detailed precision necessary for complex, domain-specific applications such as medical VQA. Our representation model, BIND: BLIVA Integrated with Dense Encoding, extends prior multimodal work by refining the joint embedding space through dense, query-token-based encodings inspired by contrastive pretraining techniques. This refined encoder powers Med-GRIM, a model designed for medical VQA tasks that leverages graph-based retrieval and prompt engineering to integrate domain-specific knowledge. Rather than relying on compute-heavy fine-tuning of vision and language models on specific datasets, Med-GRIM applies a low-compute, modular workflow with small language models (SLMs) for efficiency. Med-GRIM employs prompt-based retrieval to dynamically inject relevant knowledge, ensuring both accuracy and robustness in its responses. By assigning distinct roles to each agent within the VQA system, Med-GRIM achieves large language model performance at a fraction of the computational cost. Additionally, to support scalable research in zero-shot multimodal medical applications, we introduce DermaGraph, a novel Graph-RAG dataset comprising diverse dermatological conditions. This dataset facilitates both multimodal and unimodal querying. The code and dataset are available at: https://github.com/Rakesh-123-cryp/Med-GRIM.git