# EndoMatcher: Generalizable Endoscopic Image Matcher via Multi-Domain Pre-training for Robot-Assisted Surgery

arXiv: https://arxiv.org/abs/2508.05205 · HTML: https://mlsanity.com/paper/2508.05205/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 38 of its 54 references that are in the map.
- First posted on arXiv 7 Aug 2025.

## Builds on (most cited first, 30 of 38)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Microsoft COCO: Common Objects in Context](https://mlsanity.com/paper/1405.0312/) (2014)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [DINOv2: Learning Robust Visual Features without Supervision](https://mlsanity.com/paper/2304.07193/) (2023)
- [ScanNet: Richly-annotated 3D Reconstructions of Indoor Scenes](https://mlsanity.com/paper/1702.04405/) (2017)
- [Vision Transformers for Dense Prediction](https://mlsanity.com/paper/2103.13413/) (2021)
- [Towards Robust Monocular Depth Estimation: Mixing Datasets for Zero-shot Cross-dataset Transfer](https://mlsanity.com/paper/1907.01341/) (2019)
- [SuperGlue: Learning Feature Matching with Graph Neural Networks](https://mlsanity.com/paper/1911.11763/) (2019)
- [Depth Anything V2](https://mlsanity.com/paper/2406.09414/) (2024)
- [Depth Anything: Unleashing the Power of Large-Scale Unlabeled Data](https://mlsanity.com/paper/2401.10891/) (2024)
- [SuperPoint: Self-Supervised Interest Point Detection and Description](https://mlsanity.com/paper/1712.07629/) (2017)
- [LoFTR: Detector-Free Local Feature Matching with Transformers](https://mlsanity.com/paper/2104.00680/) (2021)
- [MegaDepth: Learning Single-View Depth Prediction from Internet Photos](https://mlsanity.com/paper/1804.00607/) (2018)
- [LightGlue: Local Feature Matching at Light Speed](https://mlsanity.com/paper/2306.13643/) (2023)
- [RefineNet: Multi-Path Refinement Networks for High-Resolution Semantic Segmentation](https://mlsanity.com/paper/1611.06612/) (2016)
- [Past, Present, and Future of Simultaneous Localization And Mapping: Towards the Robust-Perception Age](https://mlsanity.com/paper/1606.05830/) (2016)
- [Metric3Dv2: A Versatile Monocular Geometric Foundation Model for Zero-shot Metric Depth and Surface Normal Estimation](https://mlsanity.com/paper/2404.15506/) (2024)
- [MiDaS v3.1 -- A Model Zoo for Robust Monocular Relative Depth Estimation](https://mlsanity.com/paper/2307.14460/) (2023)
- [ASpanFormer: Detector-Free Image Matching with Adaptive Span Transformer](https://mlsanity.com/paper/2208.14201/) (2022)
- [Stereo Correspondence and Reconstruction of Endoscopic Data Challenge](https://mlsanity.com/paper/2101.01133/) (2021)
- [PDC-Net+: Enhanced Probabilistic Dense Correspondence Network](https://mlsanity.com/paper/2109.13912/) (2021)
- [Colonoscopy 3D Video Dataset with Paired Depth from 2D-3D Registration](https://mlsanity.com/paper/2206.08903/) (2022)
- [GIM: Learning Generalizable Image Matcher From Internet Videos](https://mlsanity.com/paper/2402.11095/) (2024)
- [OmniGlue: Generalizable Feature Matching with Foundation Model Guidance](https://mlsanity.com/paper/2405.12979/) (2024)
- [EndoMapper dataset of complete calibrated endoscopy procedures](https://mlsanity.com/paper/2204.14240/) (2022)
- [Few-View Object Reconstruction with Unknown Categories and Camera Poses](https://mlsanity.com/paper/2212.04492/) (2022)
- [A case for using rotation invariant features in state of the art feature matchers](https://mlsanity.com/paper/2204.10144/) (2022)
- [Extremely Dense Point Correspondences using a Learned Feature Descriptor](https://mlsanity.com/paper/2003.00619/) (2020)
- [End2End Multi-View Feature Matching with Differentiable Pose Optimization](https://mlsanity.com/paper/2205.01694/) (2022)

## Abstract (arXiv)

Generalizable dense feature matching in endoscopic images is crucial for robot-assisted tasks, including 3D reconstruction, navigation, and surgical scene understanding. Yet, it remains a challenge due to difficult visual conditions (e.g., weak textures, large viewpoint variations) and a scarcity of annotated data. To address these challenges, we propose EndoMatcher, a generalizable endoscopic image matcher via large-scale, multi-domain data pre-training. To address difficult visual conditions, EndoMatcher employs a two-branch Vision Transformer to extract multi-scale features, enhanced by dual interaction blocks for robust correspondence learning. To overcome data scarcity and improve domain diversity, we construct Endo-Mix6, the first multi-domain dataset for endoscopic matching. Endo-Mix6 consists of approximately 1.2M real and synthetic image pairs across six domains, with correspondence labels generated using Structure-from-Motion and simulated transformations. The diversity and scale of Endo-Mix6 introduce new challenges in training stability due to significant variations in dataset sizes, distribution shifts, and error imbalance. To address them, a progressive multi-objective training strategy is employed to promote balanced learning and improve representation quality across domains. This enables EndoMatcher to generalize across unseen organs and imaging conditions in a zero-shot fashion. Extensive zero-shot matching experiments demonstrate that EndoMatcher increases the number of inlier matches by 140.69% and 201.43% on the Hamlyn and Bladder datasets over state-of-the-art methods, respectively, and improves the Matching Direction Prediction Accuracy (MDPA) by 9.40% on the Gastro-Matching dataset, achieving dense and accurate matching under challenging endoscopic conditions. The code is publicly available at https://github.com/Beryl2000/EndoMatcher.