# Beyond the Leaderboard: Rethinking Medical Benchmarks for Large Language Models

arXiv: https://arxiv.org/abs/2508.04325 · HTML: https://mlsanity.com/paper/2508.04325/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning.
- Builds on 9 of its 87 references that are in the map.
- First posted on arXiv 6 Aug 2025.

## Placed in

- LLM reasoning / [Clinical and biomedical applications](https://mlsanity.com/lr/clinical-and-biomedical-applications/)

## Builds on (most cited first, 9 of 9)

- [PathVQA: 30000+ Questions for Medical Visual Question Answering](https://mlsanity.com/paper/2003.10286/) (2020)
- [PMC-VQA: Visual Instruction Tuning for Medical Visual Question Answering](https://mlsanity.com/paper/2305.10415/) (2023)
- [MedHELM: Holistic Evaluation of Large Language Models for Medical Tasks](https://mlsanity.com/paper/2505.23802/) (2025)
- [A Survey on Medical Large Language Models: Technology, Application, Trustworthiness, and Future Directions](https://mlsanity.com/paper/2406.03712/) (2024)
- [MEDIC: Comprehensive Evaluation of Leading Indicators for LLM Safety and Utility in Clinical Applications](https://mlsanity.com/paper/2409.07314/) (2024)
- [Large Language Model Benchmarks in Medical Tasks](https://mlsanity.com/paper/2410.21348/) (2024)
- [Knowledge Distillation of Russian Language Models with Reduction of Vocabulary](https://mlsanity.com/paper/2205.02340/) (2022)
- [RiskAgent: Synergizing Language Models with Validated Tools for Evidence-Based Risk Prediction](https://mlsanity.com/paper/2503.03802/) (2025)
- [FOSS solution for Molecular Dynamics Simulation Automation and Collaboration with MDSGAT](https://mlsanity.com/paper/2503.05113/) (2025)

## Abstract (arXiv)

Large language models (LLMs) show significant potential in healthcare, prompting numerous benchmarks to evaluate their capabilities. However, concerns persist regarding the reliability of these benchmarks, which often lack clinical fidelity, robust data management, and safety-oriented evaluation metrics. To address these shortcomings, we introduce MedCheck, the first lifecycle-oriented assessment framework specifically designed for medical benchmarks. Our framework deconstructs a benchmark's development into five continuous stages, from design to governance, and provides a comprehensive checklist of 46 medically-tailored criteria. Using MedCheck, we conducted an in-depth empirical evaluation of 53 medical LLM benchmarks. Our analysis uncovers widespread, systemic issues, including a profound disconnect from clinical practice, a crisis of data integrity due to unmitigated contamination risks, and a systematic neglect of safety-critical evaluation dimensions like model robustness and uncertainty awareness. Based on these findings, MedCheck serves as both a diagnostic tool for existing benchmarks and an actionable guideline to foster a more standardized, reliable, and transparent approach to evaluating AI in healthcare.