# PET2Rep: Towards Vision-Language Model-Drived Automated Radiology Report Generation for Positron Emission Tomography

arXiv: https://arxiv.org/abs/2508.04062 · HTML: https://mlsanity.com/paper/2508.04062/

## Key facts

- Cited by 7 papers in the map (data through 14 Oct 2026).
- Builds on 24 of its 51 references that are in the map.
- First posted on arXiv 6 Aug 2025.

## Builds on (most cited first, 24 of 24)

- [Qwen2.5-VL Technical Report](https://mlsanity.com/paper/2502.13923/) (2025)
- [Gemini 2.5: Pushing the Frontier with Advanced Reasoning, Multimodality, Long Context, and Next Generation Agentic Capabilities](https://mlsanity.com/paper/2507.06261/) (2025)
- [InternVL3: Exploring Advanced Training and Test-Time Recipes for Open-Source Multimodal Models](https://mlsanity.com/paper/2504.10479/) (2025)
- [LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day](https://mlsanity.com/paper/2306.00890/) (2023)
- [GLM: General Language Model Pretraining with Autoregressive Blank Infilling](https://mlsanity.com/paper/2103.10360/) (2021)
- [Vision-Language Models for Vision Tasks: A Survey](https://mlsanity.com/paper/2304.00685/) (2023)
- [Yi: Open Foundation Models by 01.AI](https://mlsanity.com/paper/2403.04652/) (2024)
- [DeepSeek-VL2: Mixture-of-Experts Vision-Language Models for Advanced Multimodal Understanding](https://mlsanity.com/paper/2412.10302/) (2024)
- [Med-Flamingo: a Multimodal Medical Few-shot Learner](https://mlsanity.com/paper/2307.15189/) (2023)
- [Lingshu: A Generalist Foundation Model for Unified Multimodal Medical Understanding and Reasoning](https://mlsanity.com/paper/2506.07044/) (2025)
- [On the Automatic Generation of Medical Imaging Reports](https://mlsanity.com/paper/1711.08195/) (2017)
- [HuatuoGPT-Vision, Towards Injecting Medical Visual Knowledge into Multimodal LLMs at Scale](https://mlsanity.com/paper/2406.19280/) (2024)
- [Generalist Foundation Models from a Multimodal Dataset for 3D Computed Tomography](https://mlsanity.com/paper/2403.17834/) (2024)
- [VisualGPT: Data-efficient Adaptation of Pretrained Language Models for Image Captioning](https://mlsanity.com/paper/2102.10407/) (2021)
- [CT2Rep: Automated Radiology Report Generation for 3D Medical Imaging](https://mlsanity.com/paper/2403.06801/) (2024)
- [GMAI-MMBench: A Comprehensive Multimodal Evaluation Benchmark Towards General Medical AI](https://mlsanity.com/paper/2408.03361/) (2024)
- [Qilin-Med-VL: Towards Chinese Large Vision-Language Model for General Healthcare](https://mlsanity.com/paper/2310.17956/) (2023)
- [RadGPT: Constructing 3D Image-Text Tumor Datasets](https://mlsanity.com/paper/2501.04678/) (2025)
- [Large Language Model with Region-guided Referring and Grounding for CT Report Generation](https://mlsanity.com/paper/2411.15539/) (2024)
- [MediConfusion: Can you trust your AI radiologist? Probing the reliability of multimodal medical foundation models](https://mlsanity.com/paper/2409.15477/) (2024)
- [SegAnyPET: Universal Promptable Segmentation from Positron Emission Tomography Images](https://mlsanity.com/paper/2502.14351/) (2025)
- [Taming Vision-Language Models for Medical Image Analysis: A Comprehensive Review](https://mlsanity.com/paper/2506.18378/) (2025)
- [Scaling Up Biomedical Vision-Language Models: Fine-Tuning, Instruction Tuning, and Multi-Modal Learning](https://mlsanity.com/paper/2505.17436/) (2025)
- [How Well Do Multi-modal LLMs Interpret CT Scans? An Auto-Evaluation Framework for Analyses](https://mlsanity.com/paper/2403.05680/) (2024)

## Built on by (most cited first, 7 of 7)

- [Unveiling and Bridging the Functional Perception Gap in MLLMs: Atomic Visual Alignment and Hierarchical Evaluation via PET-Bench](https://mlsanity.com/paper/2601.02737/) (2026)
- [Vision-Language Models for Automated 3D PET/CT Report Generation](https://mlsanity.com/paper/2511.20145/) (2025)
- [PET-F2I: A Comprehensive Benchmark and Parameter-Efficient Fine-Tuning of LLMs for PET/CT Report Impression Generation](https://mlsanity.com/paper/2603.10560/) (2026)
- [Region-Grounded Report Generation for 3D Medical Imaging: A Fine-Grained Dataset and Graph-Enhanced Framework](https://mlsanity.com/paper/2604.18145/) (2026)
- [MetaStructAtlas: A Grounded 3D Vision-Language Dataset and Benchmark for Functional and Structural Reasoning in Whole-Body PET/CT](https://mlsanity.com/paper/2609.03690/) (2026)
- [A Unified Vision-Language Model for PSMA PET/CT Report Generation, Visual Question Answering, and Lesion Segmentation](https://mlsanity.com/paper/2609.15603/) (2026)
- [Anatomy-preserving unpaired cone-beam CT refinement for image-guided radiotherapy using pseudo-label guided diffusion](https://mlsanity.com/paper/2610.06094/) (2026)

## Abstract (arXiv)

Positron emission tomography (PET) is a cornerstone of modern oncologic and neurologic imaging, distinguished by its unique ability to illuminate dynamic metabolic processes that transcend the anatomical focus of traditional imaging technologies. Radiology reports are essential for clinical decision making, yet their manual creation is labor-intensive and time-consuming. Recent advancements of vision-language models (VLMs) have shown strong potential in medical applications, presenting a promising avenue for automating report generation. However, existing applications of VLMs in the medical domain have predominantly focused on structural imaging modalities, while the unique characteristics of molecular PET imaging have largely been overlooked. To bridge the gap, we introduce PET2Rep, a large-scale comprehensive benchmark for evaluation of general and medical VLMs for radiology report generation for PET images. PET2Rep stands out as the first dedicated dataset for PET report generation with metabolic information, uniquely capturing whole-body image-report pairs that cover dozens of organs to fill the critical gap in existing benchmarks and mirror real-world clinical comprehensiveness. In addition to widely recognized natural language generation metrics, we introduce a series of clinical efficacy metrics to evaluate the quality of radiotracer uptake pattern description in key organs in generated reports. We conduct a head-to-head comparison of 30 cutting-edge general-purpose and medical-specialized VLMs. The results show that the current state-of-the-art VLMs perform poorly on PET report generation task, falling considerably short of fulfilling practical needs. Moreover, we identify several key insufficiency that need to be addressed to advance the development in medical applications.
