# Predict Patient Self-reported Race from Skin Histological Images

arXiv: https://arxiv.org/abs/2507.21912 · HTML: https://mlsanity.com/paper/2507.21912/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 13 of its 33 references that are in the map.
- First posted on arXiv 29 Jul 2025.

## Builds on (most cited first, 13 of 13)

- [UMAP: Uniform Manifold Approximation and Projection for Dimension Reduction](https://mlsanity.com/paper/1802.03426/) (2018)
- [Decoupled Weight Decay Regularization](https://mlsanity.com/paper/1711.05101/) (2017)
- [Attention-based Deep Multiple Instance Learning](https://mlsanity.com/paper/1802.04712/) (2018)
- [Data Efficient and Weakly Supervised Computational Pathology on Whole Slide Images](https://mlsanity.com/paper/2004.09666/) (2020)
- [Hidden Stratification Causes Clinically Meaningful Failures in Machine Learning for Medical Imaging](https://mlsanity.com/paper/1909.12475/) (2019)
- [Reading Race: AI Recognises Patient's Racial Identity In Medical Images](https://mlsanity.com/paper/2107.10356/) (2021)
- [Artificial Intelligence for Digital and Computational Pathology](https://mlsanity.com/paper/2401.06148/) (2023)
- [A Clinical Benchmark of Public Self-Supervised Pathology Foundation Models](https://mlsanity.com/paper/2407.06508/) (2024)
- [Computational Pathology at Health System Scale -- Self-Supervised Foundation Models from Three Billion Images](https://mlsanity.com/paper/2310.07033/) (2023)
- [Computational Pathology: A Survey Review and The Way Forward](https://mlsanity.com/paper/2304.05482/) (2023)
- [Risk of Bias in Chest Radiography Deep Learning Foundation Models](https://mlsanity.com/paper/2209.02965/) (2022)
- [Benchmarking Embedding Aggregation Methods in Computational Pathology: A Clinical Data Perspective](https://mlsanity.com/paper/2407.07841/) (2024)
- [Analysing race and sex bias in brain age prediction](https://mlsanity.com/paper/2309.10835/) (2023)

## Abstract (arXiv)

Artificial Intelligence (AI) has demonstrated success in computational pathology (CPath) for disease detection, biomarker classification, and prognosis prediction. However, its potential to learn unintended demographic biases, particularly those related to social determinants of health, remains understudied. This study investigates whether deep learning models can predict self-reported race from digitized dermatopathology slides and identifies potential morphological shortcuts. Using a multisite dataset with a racially diverse population, we apply an attention-based mechanism to uncover race-associated morphological features. After evaluating three dataset curation strategies to control for confounding factors, the final experiment showed that White and Black demographic groups retained high prediction performance (AUC: 0.799, 0.762), while overall performance dropped to 0.663. Attention analysis revealed the epidermis as a key predictive feature, with significant performance declines when these regions were removed. These findings highlight the need for careful data curation and bias mitigation to ensure equitable AI deployment in pathology. Code available at: https://github.com/sinai-computational-pathology/CPath_SAIF.