# Comparative Analysis of Vision Transformers and Convolutional Neural Networks for Medical Image Classification

arXiv: https://arxiv.org/abs/2507.21156 · HTML: https://mlsanity.com/paper/2507.21156/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 6 of its 8 references that are in the map.
- First posted on arXiv 24 Jul 2025.

## Builds on (most cited first, 6 of 6)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [EfficientNet: Rethinking Model Scaling for Convolutional Neural Networks](https://mlsanity.com/paper/1905.11946/) (2019)
- [Training data-efficient image transformers & distillation through attention](https://mlsanity.com/paper/2012.12877/) (2020)
- [CheXNet: Radiologist-Level Pneumonia Detection on Chest X-Rays with Deep Learning](https://mlsanity.com/paper/1711.05225/) (2017)
- [Is it Time to Replace CNNs with Transformers for Medical Images?](https://mlsanity.com/paper/2108.09038/) (2021)

## Built on by (most cited first, 1 of 1)

- [Mr3D-VL: A generalist vision language foundation model for Multiparametric 3D Magnetic Resonance Imaging](https://mlsanity.com/paper/2608.12689/) (2026)

## Abstract (arXiv)

The emergence of Vision Transformers (ViTs) has revolutionized computer vision, yet their effectiveness compared to traditional Convolutional Neural Networks (CNNs) in medical imaging remains under-explored. This study presents a comprehensive comparative analysis of CNN and ViT architectures across three critical medical imaging tasks: chest X-ray pneumonia detection, brain tumor classification, and skin cancer melanoma detection. We evaluated four state-of-the-art models - ResNet-50, EfficientNet-B0, ViT-Base, and DeiT-Small - across datasets totaling 8,469 medical images. Our results demonstrate task-specific model advantages: ResNet-50 achieved 98.37% accuracy on chest X-ray classification, DeiT-Small excelled at brain tumor detection with 92.16% accuracy, and EfficientNet-B0 led skin cancer classification at 81.84% accuracy. These findings provide crucial insights for practitioners selecting architectures for medical AI applications, highlighting the importance of task-specific architecture selection in clinical decision support systems.