# SeeDiff: Off-the-Shelf Seeded Mask Generation from Diffusion Models

arXiv: https://arxiv.org/abs/2507.19808 · HTML: https://mlsanity.com/paper/2507.19808/

## Key facts

- Cited by 5 papers in the map (data through 14 Oct 2026).
- Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models.
- Builds on 60 of its 77 references that are in the map.
- First posted on arXiv 26 Jul 2025.

## Placed in

- Diffusion models / [Medical imaging and segmentation](https://mlsanity.com/diffusion/medical-imaging-and-segmentation/)

## Builds on (most cited first, 30 of 60)

- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Microsoft COCO: Common Objects in Context](https://mlsanity.com/paper/1405.0312/) (2014)
- [Semi-Supervised Classification with Graph Convolutional Networks](https://mlsanity.com/paper/1609.02907/) (2016)
- [End-to-End Object Detection with Transformers](https://mlsanity.com/paper/2005.12872/) (2020)
- [Emerging Properties in Self-Supervised Vision Transformers](https://mlsanity.com/paper/2104.14294/) (2021)
- [Hierarchical Text-Conditional Image Generation with CLIP Latents](https://mlsanity.com/paper/2204.06125/) (2022)
- [Photorealistic Text-to-Image Diffusion Models with Deep Language Understanding](https://mlsanity.com/paper/2205.11487/) (2022)
- [A Style-Based Generator Architecture for Generative Adversarial Networks](https://mlsanity.com/paper/1812.04948/) (2018)
- [Generative Adversarial Networks](https://mlsanity.com/paper/2203.00667/) (2022)
- [Fully Convolutional Networks for Semantic Segmentation](https://mlsanity.com/paper/1411.4038/) (2014)
- [The Cityscapes Dataset for Semantic Urban Scene Understanding](https://mlsanity.com/paper/1604.01685/) (2016)
- [LAION-5B: An open large-scale dataset for training next generation image-text models](https://mlsanity.com/paper/2210.08402/) (2022)
- [GLIDE: Towards Photorealistic Image Generation and Editing with Text-Guided Diffusion Models](https://mlsanity.com/paper/2112.10741/) (2021)
- [Taming Transformers for High-Resolution Image Synthesis](https://mlsanity.com/paper/2012.09841/) (2020)
- [DeepLab: Semantic Image Segmentation with Deep Convolutional Nets, Atrous Convolution, and Fully Connected CRFs](https://mlsanity.com/paper/1606.00915/) (2016)
- [Large Scale GAN Training for High Fidelity Natural Image Synthesis](https://mlsanity.com/paper/1809.11096/) (2018)
- [Prompt-to-Prompt Image Editing with Cross Attention Control](https://mlsanity.com/paper/2208.01626/) (2022)
- [Masked-attention Mask Transformer for Universal Image Segmentation](https://mlsanity.com/paper/2112.01527/) (2021)
- [Visualizing and Understanding Convolutional Networks](https://mlsanity.com/paper/1311.2901/) (2013)
- [SegNet: A Deep Convolutional Encoder-Decoder Architecture for Image Segmentation](https://mlsanity.com/paper/1511.00561/) (2015)
- [Rethinking Semantic Segmentation from a Sequence-to-Sequence Perspective with Transformers](https://mlsanity.com/paper/2012.15840/) (2020)
- [Per-Pixel Classification is Not All You Need for Semantic Segmentation](https://mlsanity.com/paper/2107.06278/) (2021)
- [Multi-Scale Context Aggregation by Dilated Convolutions](https://mlsanity.com/paper/1511.07122/) (2015)
- [NICE: Non-linear Independent Components Estimation](https://mlsanity.com/paper/1410.8516/) (2014)
- [Label-Efficient Semantic Segmentation with Diffusion Models](https://mlsanity.com/paper/2112.03126/) (2021)
- [Learning Deconvolution Network for Semantic Segmentation](https://mlsanity.com/paper/1505.04366/) (2015)

## Built on by (most cited first, 5 of 5)

- [Making Training-Free Diffusion Segmentors Scale with the Generative Power](https://mlsanity.com/paper/2603.06178/) (2026)
- [Unlocking Diffusion Hierarchies: Adaptive Timestep Selection for Zero-Shot Segmentation](https://mlsanity.com/paper/2606.15590/) (2026)
- [Decoupled Guidance: Disentangling Subject and Context Pathways in Text-to-Image Personalization](https://mlsanity.com/paper/2607.00766/) (2026)
- [DualDiT: A Conditional Dual-Output Diffusion Transformer for Joint OCT Image and Segmentation Mask Generation](https://mlsanity.com/paper/2607.29337/) (2026)
- [Text-to-seed generation: Training-free open-vocabulary seeded semantic segmentation via re-purposing diffusion as text-guided seed generator](https://mlsanity.com/paper/2608.26624/) (2026)

## Abstract (arXiv)

Entrusted with the goal of pixel-level object classification, the semantic segmentation networks entail the laborious preparation of pixel-level annotation masks. To obtain pixel-level annotation masks for a given class without human efforts, recent few works have proposed to generate pairs of images and annotation masks by employing image and text relationships modeled by text-to-image generative models, especially Stable Diffusion. However, these works do not fully exploit the capability of text-guided Diffusion models and thus require a pre-trained segmentation network, careful text prompt tuning, or the training of a segmentation network to generate final annotation masks. In this work, we take a closer look at attention mechanisms of Stable Diffusion, from which we draw connections with classical seeded segmentation approaches. In particular, we show that cross-attention alone provides very coarse object localization, which however can provide initial seeds. Then, akin to region expansion in seeded segmentation, we utilize the semantic-correspondence-modeling capability of self-attention to iteratively spread the attention to the whole class from the seeds using multi-scale self-attention maps. We also observe that a simple-text-guided synthetic image often has a uniform background, which is easier to find correspondences, compared to complex-structured objects. Thus, we further refine a mask using a more accurate background mask. Our proposed method, dubbed SeeDiff, generates high-quality masks off-the-shelf from Stable Diffusion, without additional training procedure, prompt tuning, or a pre-trained segmentation network.