# Differentiating hype from practical applications of large language models in medicine -- a primer for healthcare professionals

arXiv: https://arxiv.org/abs/2507.19567 · HTML: https://mlsanity.com/paper/2507.19567/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 8 of its 30 references that are in the map.
- First posted on arXiv 25 Jul 2025.

## Builds on (most cited first, 8 of 8)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [Scalable Extraction of Training Data from (Production) Language Models](https://mlsanity.com/paper/2311.17035/) (2023)
- [Great, Now Write an Article About That: The Crescendo Multi-Turn LLM Jailbreak Attack](https://mlsanity.com/paper/2404.01833/) (2024)
- [Stealing Part of a Production Language Model](https://mlsanity.com/paper/2403.06634/) (2024)
- [Who Validates the Validators? Aligning LLM-Assisted Evaluation of LLM Outputs with Human Preferences](https://mlsanity.com/paper/2404.12272/) (2024)
- [GeneGPT: Augmenting Large Language Models with Domain Tools for Improved Access to Biomedical Information](https://mlsanity.com/paper/2304.09667/) (2023)
- [Large Language Models to Identify Social Determinants of Health in Electronic Health Records](https://mlsanity.com/paper/2308.06354/) (2023)

## Abstract (arXiv)

The medical ecosystem consists of the training of new clinicians and researchers, the practice of clinical medicine, and areas of adjacent research. There are many aspects of these domains that could benefit from the application of task automation and programmatic assistance. Machine learning and artificial intelligence techniques, including large language models (LLMs), have been promised to deliver on healthcare innovation, improving care speed and accuracy, and reducing the burden on staff for manual interventions. However, LLMs have no understanding of objective truth that is based in reality. They also represent real risks to the disclosure of protected information when used by clinicians and researchers. The use of AI in medicine in general, and the deployment of LLMs in particular, therefore requires careful consideration and thoughtful application to reap the benefits of these technologies while avoiding the dangers in each context.