# Dual Path Learning -- learning from noise and context for medical image denoising

arXiv: https://arxiv.org/abs/2507.19035 · HTML: https://mlsanity.com/paper/2507.19035/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 6 of its 25 references that are in the map.
- First posted on arXiv 25 Jul 2025.

## Builds on (most cited first, 6 of 6)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Low-Dose CT with a Residual Encoder-Decoder Convolutional Neural Network (RED-CNN)](https://mlsanity.com/paper/1702.00288/) (2017)
- [The Brain Tumor Segmentation (BraTS) Challenge 2023: Glioma Segmentation in Sub-Saharan Africa Patient Population (BraTS-Africa)](https://mlsanity.com/paper/2305.19369/) (2023)
- [DU-GAN: Generative Adversarial Networks with Dual-Domain U-Net Based Discriminators for Low-Dose CT Denoising](https://mlsanity.com/paper/2108.10772/) (2021)
- [Retinal OCT Denoising with Pseudo-Multimodal Fusion Network](https://mlsanity.com/paper/2107.04288/) (2021)
- [Two-stage Deep Denoising with Self-guided Noise Attention for Multimodal Medical Images](https://mlsanity.com/paper/2503.06827/) (2025)

## Built on by (most cited first, 1 of 1)

- [Establishing Stochastic Object Models from Noisy Data via Ambient Measurement-Integrated Diffusion](https://mlsanity.com/paper/2512.14187/) (2025)

## Abstract (arXiv)

Medical imaging plays a critical role in modern healthcare, enabling clinicians to accurately diagnose diseases and develop effective treatment plans. However, noise, often introduced by imaging devices, can degrade image quality, leading to misinterpretation and compromised clinical outcomes. Existing denoising approaches typically rely either on noise characteristics or on contextual information from the image. Moreover, they are commonly developed and evaluated for a single imaging modality and noise type. Motivated by Geng et.al CNCL, which integrates both noise and context, this study introduces a Dual-Pathway Learning (DPL) model architecture that effectively denoises medical images by leveraging both sources of information and fusing them to generate the final output. DPL is evaluated across multiple imaging modalities and various types of noise, demonstrating its robustness and generalizability. DPL improves PSNR by 3.35% compared to the baseline UNet when evaluated on Gaussian noise and trained across all modalities. The code is available at 10.5281/zenodo.15836053.