# Towards Facilitated Fairness Assessment of AI-based Skin Lesion Classifiers Through GenAI-based Image Synthesis

arXiv: https://arxiv.org/abs/2507.17860 · HTML: https://mlsanity.com/paper/2507.17860/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 41 of its 65 references that are in the map.
- First posted on arXiv 23 Jul 2025.

## Builds on (most cited first, 30 of 41)

- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [DINOv2: Learning Robust Visual Features without Supervision](https://mlsanity.com/paper/2304.07193/) (2023)
- [Masked Autoencoders Are Scalable Vision Learners](https://mlsanity.com/paper/2111.06377/) (2021)
- [Scalable Diffusion Models with Transformers](https://mlsanity.com/paper/2212.09748/) (2022)
- [A Style-Based Generator Architecture for Generative Adversarial Networks](https://mlsanity.com/paper/1812.04948/) (2018)
- [Image-to-Image Translation with Conditional Adversarial Networks](https://mlsanity.com/paper/1611.07004/) (2016)
- [DreamBooth: Fine Tuning Text-to-Image Diffusion Models for Subject-Driven Generation](https://mlsanity.com/paper/2208.12242/) (2022)
- [Unsupervised Representation Learning with Deep Convolutional Generative Adversarial Networks](https://mlsanity.com/paper/1511.06434/) (2015)
- [Equality of Opportunity in Supervised Learning](https://mlsanity.com/paper/1610.02413/) (2016)
- [Training Generative Adversarial Networks with Limited Data](https://mlsanity.com/paper/2006.06676/) (2020)
- [Vision-Language Models for Vision Tasks: A Survey](https://mlsanity.com/paper/2304.00685/) (2023)
- [Skin Lesion Analysis Toward Melanoma Detection 2018: A Challenge Hosted by the International Skin Imaging Collaboration (ISIC)](https://mlsanity.com/paper/1902.03368/) (2019)
- [Skin Lesion Analysis Toward Melanoma Detection: A Challenge at the 2017 International Symposium on Biomedical Imaging (ISBI), Hosted by the International Skin Imaging Collaboration (ISIC)](https://mlsanity.com/paper/1710.05006/) (2017)
- [Reconstruction vs. Generation: Taming Optimization Dilemma in Latent Diffusion Models](https://mlsanity.com/paper/2501.01423/) (2025)
- [BCN20000: Dermoscopic Lesions in the Wild](https://mlsanity.com/paper/1908.02288/) (2019)
- [Deep Generative Image Models using a Laplacian Pyramid of Adversarial Networks](https://mlsanity.com/paper/1506.05751/) (2015)
- [Skin Lesion Analysis toward Melanoma Detection: A Challenge at the International Symposium on Biomedical Imaging (ISBI) 2016, hosted by the International Skin Imaging Collaboration (ISIC)](https://mlsanity.com/paper/1605.01397/) (2016)
- [Deep Learning is Robust to Massive Label Noise](https://mlsanity.com/paper/1705.10694/) (2017)
- [A Patient-Centric Dataset of Images and Metadata for Identifying Melanomas Using Clinical Context](https://mlsanity.com/paper/2008.07360/) (2020)
- [DermGAN: Synthetic Generation of Clinical Skin Images with Pathology](https://mlsanity.com/paper/1911.08716/) (2019)
- [Estimating and Improving Fairness with Adversarial Learning](https://mlsanity.com/paper/2103.04243/) (2021)
- [Detecting Melanoma Fairly: Skin Tone Detection and Debiasing for Skin Lesion Classification](https://mlsanity.com/paper/2202.02832/) (2022)
- [Skin Lesion Synthesis with Generative Adversarial Networks](https://mlsanity.com/paper/1902.03253/) (2019)
- [XCoOp: Explainable Prompt Learning for Computer-Aided Diagnosis via Concept-guided Context Optimization](https://mlsanity.com/paper/2403.09410/) (2024)
- [ExAID: A Multimodal Explanation Framework for Computer-Aided Diagnosis of Skin Lesions](https://mlsanity.com/paper/2201.01249/) (2022)
- [Melanoma Detection using Adversarial Training and Deep Transfer Learning](https://mlsanity.com/paper/2004.06824/) (2020)
- [Reveal to Revise: An Explainable AI Life Cycle for Iterative Bias Correction of Deep Models](https://mlsanity.com/paper/2303.12641/) (2023)
- [MelanoGANs: High Resolution Skin Lesion Synthesis with GANs](https://mlsanity.com/paper/1804.04338/) (2018)

## Abstract (arXiv)

Recent advances in deep learning and on-device inference could transform routine screening for skin cancers. Along with the anticipated benefits of this technology, potential dangers arise from unforeseen and inherent biases. A significant obstacle is building evaluation datasets that accurately reflect key demographics, including sex, age, and race, as well as other underrepresented groups. To address this, we train a state-of-the-art generative model to generate synthetic data in a controllable manner to assess the fairness of publicly available skin cancer classifiers. To evaluate whether synthetic images can be used as a fairness testing dataset, we prepare a real-image dataset (MILK10K) as a benchmark and compare the True Positive Rate result of three models (DeepGuide, MelaNet, and SkinLesionDensnet). As a result, the classification tendencies observed in each model when tested on real and generated images showed similar patterns across different attribute data sets. We confirm that highly realistic synthetic images facilitate model fairness verification.