# CAPRI-CT: Causal Analysis and Predictive Reasoning for Image Quality Optimization in Computed Tomography

arXiv: https://arxiv.org/abs/2507.17420 · HTML: https://mlsanity.com/paper/2507.17420/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 9 of its 17 references that are in the map.
- First posted on arXiv 23 Jul 2025.

## Builds on (most cited first, 9 of 9)

- [Deep Structural Causal Models for Tractable Counterfactual Inference](https://mlsanity.com/paper/2006.06485/) (2020)
- [Causality matters in medical imaging](https://mlsanity.com/paper/1912.08142/) (2019)
- [Causal Machine Learning: A Survey and Open Problems](https://mlsanity.com/paper/2206.15475/) (2022)
- [Evaluating and Mitigating Bias in Image Classifiers: A Causal Perspective Using Counterfactuals](https://mlsanity.com/paper/2009.08270/) (2020)
- [A Review of Causality for Learning Algorithms in Medical Image Analysis](https://mlsanity.com/paper/2206.05498/) (2022)
- [No Fair Lunch: A Causal Perspective on Dataset Bias in Machine Learning for Medical Imaging](https://mlsanity.com/paper/2307.16526/) (2023)
- [Explaining the Behavior of Black-Box Prediction Algorithms with Causal Learning](https://mlsanity.com/paper/2006.02482/) (2020)
- [Latent Causal Modeling for 3D Brain MRI Counterfactuals](https://mlsanity.com/paper/2409.05585/) (2024)
- [MAMBO-NET: Multi-Causal Aware Modeling Backdoor-Intervention Optimization for Medical Image Segmentation Network](https://mlsanity.com/paper/2505.21874/) (2025)

## Built on by (most cited first, 1 of 1)

- [Causal Transfer in Medical Image Analysis](https://mlsanity.com/paper/2603.24388/) (2026)

## Abstract (arXiv)

In computed tomography (CT), achieving high image quality while minimizing radiation exposure remains a key clinical challenge. This paper presents CAPRI-CT, a novel causal-aware deep learning framework for Causal Analysis and Predictive Reasoning for Image Quality Optimization in CT imaging. CAPRI-CT integrates image data with acquisition metadata (such as tube voltage, tube current, and contrast agent types) to model the underlying causal relationships that influence image quality. An ensemble of Variational Autoencoders (VAEs) is employed to extract meaningful features and generate causal representations from observational data, including CT images and associated imaging parameters. These input features are fused to predict the Signal-to-Noise Ratio (SNR) and support counterfactual inference, enabling what-if simulations, such as changes in contrast agents (types and concentrations) or scan parameters. CAPRI-CT is trained and validated using an ensemble learning approach, achieving strong predictive performance. By facilitating both prediction and interpretability, CAPRI-CT provides actionable insights that could help radiologists and technicians design more efficient CT protocols without repeated physical scans. The source code and dataset are publicly available at https://github.com/SnehaGeorge22/capri-ct.