# MyGO: Make your Goals Obvious, Avoiding Semantic Confusion in Prostate Cancer Lesion Region Segmentation

arXiv: https://arxiv.org/abs/2507.17269 · HTML: https://mlsanity.com/paper/2507.17269/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 16 of its 36 references that are in the map.
- First posted on arXiv 23 Jul 2025.

## Builds on (most cited first, 16 of 16)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Mask R-CNN](https://mlsanity.com/paper/1703.06870/) (2017)
- [V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentation](https://mlsanity.com/paper/1606.04797/) (2016)
- [Attention U-Net: Learning Where to Look for the Pancreas](https://mlsanity.com/paper/1804.03999/) (2018)
- [Exploring Self-attention for Image Recognition](https://mlsanity.com/paper/2004.13621/) (2020)
- [UCTransNet: Rethinking the Skip Connections in U-Net from a Channel-wise Perspective with Transformer](https://mlsanity.com/paper/2109.04335/) (2021)
- [Medical Image Segmentation Review: The success of U-Net](https://mlsanity.com/paper/2211.14830/) (2022)
- [U-KAN Makes Strong Backbone for Medical Image Segmentation and Generation](https://mlsanity.com/paper/2406.02918/) (2024)
- [The Importance of Skip Connections in Biomedical Image Segmentation](https://mlsanity.com/paper/1608.04117/) (2016)
- [On the Integration of Self-Attention and Convolution](https://mlsanity.com/paper/2111.14556/) (2021)
- [Vision-Based UAV Self-Positioning in Low-Altitude Urban Environments](https://mlsanity.com/paper/2201.09201/) (2022)
- [Self-positioning Point-based Transformer for Point Cloud Understanding](https://mlsanity.com/paper/2303.16450/) (2023)
- [CFPNet-M: A Light-Weight Encoder-Decoder Based Network for Multimodal Biomedical Image Real-Time Segmentation](https://mlsanity.com/paper/2105.04075/) (2021)

## Abstract (arXiv)

Early diagnosis and accurate identification of lesion location and progression in prostate cancer (PCa) are critical for assisting clinicians in formulating effective treatment strategies. However, due to the high semantic homogeneity between lesion and non-lesion areas, existing medical image segmentation methods often struggle to accurately comprehend lesion semantics, resulting in the problem of semantic confusion. To address this challenge, we propose a novel Pixel Anchor Module, which guides the model to discover a sparse set of feature anchors that serve to capture and interpret global contextual information. This mechanism enhances the model's nonlinear representation capacity and improves segmentation accuracy within lesion regions. Moreover, we design a self-attention-based Top_k selection strategy to further refine the identification of these feature anchors, and incorporate a focal loss function to mitigate class imbalance, thereby facilitating more precise semantic interpretation across diverse regions. Our method achieves state-of-the-art performance on the PI-CAI dataset, demonstrating 69.73% IoU and 74.32% Dice scores, and significantly improving prostate cancer lesion detection.