# A Hybrid CNN-VSSM model for Multi-View, Multi-Task Mammography Analysis: Robust Diagnosis with Attention-Based Fusion

arXiv: https://arxiv.org/abs/2507.16955 · HTML: https://mlsanity.com/paper/2507.16955/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 18 of its 34 references that are in the map.
- First posted on arXiv 22 Jul 2025.

## Builds on (most cited first, 18 of 18)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Swin Transformer: Hierarchical Vision Transformer using Shifted Windows](https://mlsanity.com/paper/2103.14030/) (2021)
- [Mamba: Linear-Time Sequence Modeling with Selective State Spaces](https://mlsanity.com/paper/2312.00752/) (2023)
- [Efficiently Modeling Long Sequences with Structured State Spaces](https://mlsanity.com/paper/2111.00396/) (2021)
- [VMamba: Visual State Space Model](https://mlsanity.com/paper/2401.10166/) (2024)
- [VM-UNet: Vision Mamba UNet for Medical Image Segmentation](https://mlsanity.com/paper/2402.02491/) (2024)
- [Transformers in Medical Imaging: A Survey](https://mlsanity.com/paper/2201.09873/) (2022)
- [MedMamba: Vision Mamba for Medical Image Classification](https://mlsanity.com/paper/2403.03849/) (2024)
- [VinDr-Mammo: A large-scale benchmark dataset for computer-aided diagnosis in full-field digital mammography](https://mlsanity.com/paper/2203.11205/) (2022)
- [Multi-view analysis of unregistered medical images using cross-view transformers](https://mlsanity.com/paper/2103.11390/) (2021)
- [Act Like a Radiologist: Towards Reliable Multi-view Correspondence Reasoning for Mammogram Mass Detection](https://mlsanity.com/paper/2105.10160/) (2021)
- [MV-Swin-T: Mammogram Classification with Multi-view Swin Transformer](https://mlsanity.com/paper/2402.16298/) (2024)
- [Transformers Improve Breast Cancer Diagnosis from Unregistered Multi-View Mammograms](https://mlsanity.com/paper/2206.10096/) (2022)
- [Delving into Ipsilateral Mammogram Assessment under Multi-View Network](https://mlsanity.com/paper/2309.02197/) (2023)
- [MammoDG: Generalisable Deep Learning Breaks the Limits of Cross-Domain Multi-Center Breast Cancer Screening](https://mlsanity.com/paper/2308.01057/) (2023)
- [Transformers-based architectures for stroke segmentation: A review](https://mlsanity.com/paper/2403.18637/) (2024)
- [Deep models for stroke segmentation: do complex architectures always perform better?](https://mlsanity.com/paper/2403.17177/) (2024)

## Built on by (most cited first, 2 of 2)

- [MammoClean: Toward Reproducible and Bias-Aware AI in Mammography through Dataset Harmonization](https://mlsanity.com/paper/2511.02400/) (2025)
- [Energy-Mamba: A Physics-Constrained State-Space Model for Medical Image Classification](https://mlsanity.com/paper/2608.19813/) (2026)

## Abstract (arXiv)

Early and accurate interpretation of screening mammograms is essential for effective breast cancer detection, yet it remains a complex challenge due to subtle imaging findings and diagnostic ambiguity. Many existing AI approaches fall short by focusing on single view inputs or single-task outputs, limiting their clinical utility. To address these limitations, we propose a novel multi-view, multitask hybrid deep learning framework that processes all four standard mammography views and jointly predicts diagnostic labels and BI-RADS scores for each breast. Our architecture integrates a hybrid CNN VSSM backbone, combining convolutional encoders for rich local feature extraction with Visual State Space Models (VSSMs) to capture global contextual dependencies. To improve robustness and interpretability, we incorporate a gated attention-based fusion module that dynamically weights information across views, effectively handling cases with missing data. We conduct extensive experiments across diagnostic tasks of varying complexity, benchmarking our proposed hybrid models against baseline CNN architectures and VSSM models in both single task and multi task learning settings. Across all tasks, the hybrid models consistently outperform the baselines. In the binary BI-RADS 1 vs. 5 classification task, the shared hybrid model achieves an AUC of 0.9967 and an F1 score of 0.9830. For the more challenging ternary classification, it attains an F1 score of 0.7790, while in the five-class BI-RADS task, the best F1 score reaches 0.4904. These results highlight the effectiveness of the proposed hybrid framework and underscore both the potential and limitations of multitask learning for improving diagnostic performance and enabling clinically meaningful mammography analysis.
