# Evaluating the Effectiveness of Cost-Efficient Large Language Models in Benchmark Biomedical Tasks

arXiv: https://arxiv.org/abs/2507.14045 · HTML: https://mlsanity.com/paper/2507.14045/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 20 of its 27 references that are in the map.
- First posted on arXiv 18 Jul 2025.

## Builds on (most cited first, 20 of 20)

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- [Qwen2-VL: Enhancing Vision-Language Model's Perception of the World at Any Resolution](https://mlsanity.com/paper/2409.12191/) (2024)
- [Mistral 7B](https://mlsanity.com/paper/2310.06825/) (2023)
- [Phi-3 Technical Report: A Highly Capable Language Model Locally on Your Phone](https://mlsanity.com/paper/2404.14219/) (2024)
- [PubMedQA: A Dataset for Biomedical Research Question Answering](https://mlsanity.com/paper/1909.06146/) (2019)
- [PaLM 2 Technical Report](https://mlsanity.com/paper/2305.10403/) (2023)
- [Janus-Pro: Unified Multimodal Understanding and Generation with Data and Model Scaling](https://mlsanity.com/paper/2501.17811/) (2025)
- [PathVQA: 30000+ Questions for Medical Visual Question Answering](https://mlsanity.com/paper/2003.10286/) (2020)
- [A Systematic Study and Comprehensive Evaluation of ChatGPT on Benchmark Datasets](https://mlsanity.com/paper/2305.18486/) (2023)
- [Opportunities and Challenges for ChatGPT and Large Language Models in Biomedicine and Health](https://mlsanity.com/paper/2306.10070/) (2023)
- [A Systematic Survey and Critical Review on Evaluating Large Language Models: Challenges, Limitations, and Recommendations](https://mlsanity.com/paper/2407.04069/) (2024)
- [Question-Driven Summarization of Answers to Consumer Health Questions](https://mlsanity.com/paper/2005.09067/) (2020)
- [A Comprehensive Evaluation of Large Language Models on Benchmark Biomedical Text Processing Tasks](https://mlsanity.com/paper/2310.04270/) (2023)
- [Tiny Titans: Can Smaller Large Language Models Punch Above Their Weight in the Real World for Meeting Summarization?](https://mlsanity.com/paper/2402.00841/) (2024)
- [Improving Automatic Evaluation of Large Language Models (LLMs) in Biomedical Relation Extraction via LLMs-as-the-Judge](https://mlsanity.com/paper/2506.00777/) (2025)

## Built on by (most cited first, 2 of 2)

- [DACIP-RC: Domain Adaptive Continual Instruction Pre-Training via Reading Comprehension on Business Conversations](https://mlsanity.com/paper/2510.08152/) (2025)
- [Deploying Tiny LVLM Judges for Real-World Evaluation of Chart Models: Lessons Learned and Best Practices](https://mlsanity.com/paper/2510.07545/) (2025)

## Abstract (arXiv)

This paper presents a comprehensive evaluation of cost-efficient Large Language Models (LLMs) for diverse biomedical tasks spanning both text and image modalities. We evaluated a range of closed-source and open-source LLMs on tasks such as biomedical text classification and generation, question answering, and multimodal image processing. Our experimental findings indicate that there is no single LLM that can consistently outperform others across all tasks. Instead, different LLMs excel in different tasks. While some closed-source LLMs demonstrate strong performance on specific tasks, their open-source counterparts achieve comparable results (sometimes even better), with additional benefits like faster inference and enhanced privacy. Our experimental results offer valuable insights for selecting models that are optimally suited for specific biomedical applications.