# BreastSegNet: Multi-label Segmentation of Breast MRI

arXiv: https://arxiv.org/abs/2507.13604 · HTML: https://mlsanity.com/paper/2507.13604/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 8 of its 20 references that are in the map.
- First posted on arXiv 18 Jul 2025.

## Builds on (most cited first, 8 of 8)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [Swin-Unet: Unet-like Pure Transformer for Medical Image Segmentation](https://mlsanity.com/paper/2105.05537/) (2021)
- [nnU-Net Revisited: A Call for Rigorous Validation in 3D Medical Image Segmentation](https://mlsanity.com/paper/2404.09556/) (2024)
- [TotalSegmentator MRI: Robust Sequence-independent Segmentation of Multiple Anatomic Structures in MRI](https://mlsanity.com/paper/2405.19492/) (2024)
- [SegmentAnyBone: A Universal Model that Segments Any Bone at Any Location on MRI](https://mlsanity.com/paper/2401.12974/) (2024)
- [Breast density in MRI: an AI-based quantification and relationship to assessment in mammography](https://mlsanity.com/paper/2504.15192/) (2025)
- [GuidedMorph: Two-Stage Deformable Registration for Breast MRI](https://mlsanity.com/paper/2505.13414/) (2025)

## Built on by (most cited first, 1 of 1)

- [LegSegNet: A Public Deep Learning System for Lower Extremity CT Tissue Segmentation and Quantification](https://mlsanity.com/paper/2605.30829/) (2026)

## Abstract (arXiv)

Breast MRI provides high-resolution imaging critical for breast cancer screening and preoperative staging. However, existing segmentation methods for breast MRI remain limited in scope, often focusing on only a few anatomical structures, such as fibroglandular tissue or tumors, and do not cover the full range of tissues seen in scans. This narrows their utility for quantitative analysis. In this study, we present BreastSegNet, a multi-label segmentation algorithm for breast MRI that covers nine anatomical labels: fibroglandular tissue (FGT), vessel, muscle, bone, lesion, lymph node, heart, liver, and implant. We manually annotated a large set of 1123 MRI slices capturing these structures with detailed review and correction from an expert radiologist. Additionally, we benchmark nine segmentation models, including U-Net, SwinUNet, UNet++, SAM, MedSAM, and nnU-Net with multiple ResNet-based encoders. Among them, nnU-Net ResEncM achieves the highest average Dice scores of 0.694 across all labels. It performs especially well on heart, liver, muscle, FGT, and bone, with Dice scores exceeding 0.73, and approaching 0.90 for heart and liver. All model code and weights are publicly available, and we plan to release the data at a later date.