# Graph-Based Multi-Modal Light-weight Network for Adaptive Brain Tumor Segmentation

arXiv: https://arxiv.org/abs/2507.09995 · HTML: https://mlsanity.com/paper/2507.09995/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 10 of its 26 references that are in the map.
- First posted on arXiv 14 Jul 2025.

## Builds on (most cited first, 10 of 10)

- [Mamba: Linear-Time Sequence Modeling with Selective State Spaces](https://mlsanity.com/paper/2312.00752/) (2023)
- [V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentation](https://mlsanity.com/paper/1606.04797/) (2016)
- [UNETR: Transformers for 3D Medical Image Segmentation](https://mlsanity.com/paper/2103.10504/) (2021)
- [Swin UNETR: Swin Transformers for Semantic Segmentation of Brain Tumors in MRI Images](https://mlsanity.com/paper/2201.01266/) (2022)
- [Brain Tumor Segmentation with Deep Neural Networks](https://mlsanity.com/paper/1505.03540/) (2015)
- [mmFormer: Multimodal Medical Transformer for Incomplete Multimodal Learning of Brain Tumor Segmentation](https://mlsanity.com/paper/2206.02425/) (2022)
- [SegFormer3D: an Efficient Transformer for 3D Medical Image Segmentation](https://mlsanity.com/paper/2404.10156/) (2024)
- [LATUP-Net: A Lightweight 3D Attention U-Net with Parallel Convolutions for Brain Tumor Segmentation](https://mlsanity.com/paper/2404.05911/) (2024)
- [Multimodal Information Interaction for Medical Image Segmentation](https://mlsanity.com/paper/2404.16371/) (2024)
- [MedSegMamba: 3D CNN-Mamba Hybrid Architecture for Brain Segmentation](https://mlsanity.com/paper/2409.08307/) (2024)

## Abstract (arXiv)

Multi-modal brain tumor segmentation remains challenging for practical deployment due to the high computational costs of mainstream models. In this work, we propose GMLN-BTS, a Graph-based Multi-modal interaction Lightweight Network for brain tumor segmentation. Our architecture achieves high-precision, resource-efficient segmentation through three key components. First, a Modality-Aware Adaptive Encoder (M2AE) facilitates efficient multi-scale semantic extraction. Second, a Graph-based Multi-Modal Collaborative Interaction Module (G2MCIM) leverages graph structures to model complementary cross-modal relationships. Finally, a Voxel Refinement UpSampling Module (VRUM) integrates linear interpolation with multi-scale transposed convolutions to suppress artifacts and preserve boundary details. Experimental results on BraTS 2017, 2019, and 2021 benchmarks demonstrate that GMLN-BTS achieves state-of-the-art performance among lightweight models. With only 4.58M parameters, our method reduces parameter count by 98% compared to mainstream 3D Transformers while significantly outperforming existing compact approaches.