# Crucial-Diff: A Unified Diffusion Model for Crucial Image and Annotation Synthesis in Data-scarce Scenarios

arXiv: https://arxiv.org/abs/2507.09915 · HTML: https://mlsanity.com/paper/2507.09915/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Image generation, text-to-image and editing, one of 14 directions in Diffusion models.
- Builds on 52 of its 78 references that are in the map.
- First posted on arXiv 14 Jul 2025.

## Placed in

- Diffusion models / [Image generation, text-to-image and editing](https://mlsanity.com/diffusion/image-generation-text-to-image-and-editing/)

## Builds on (most cited first, 30 of 52)

- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [Hierarchical Text-Conditional Image Generation with CLIP Latents](https://mlsanity.com/paper/2204.06125/) (2022)
- [Zero-Shot Text-to-Image Generation](https://mlsanity.com/paper/2102.12092/) (2021)
- [Generative Modeling by Estimating Gradients of the Data Distribution](https://mlsanity.com/paper/1907.05600/) (2019)
- [Improved Techniques for Training GANs](https://mlsanity.com/paper/1606.03498/) (2016)
- [SegFormer: Simple and Efficient Design for Semantic Segmentation with Transformers](https://mlsanity.com/paper/2105.15203/) (2021)
- [An Image is Worth One Word: Personalizing Text-to-Image Generation using Textual Inversion](https://mlsanity.com/paper/2208.01618/) (2022)
- [Multi-Concept Customization of Text-to-Image Diffusion](https://mlsanity.com/paper/2212.04488/) (2022)
- [Towards Total Recall in Industrial Anomaly Detection](https://mlsanity.com/paper/2106.08265/) (2021)
- [CogView: Mastering Text-to-Image Generation via Transformers](https://mlsanity.com/paper/2105.13290/) (2021)
- [AttnGAN: Fine-Grained Text to Image Generation with Attentional Generative Adversarial Networks](https://mlsanity.com/paper/1711.10485/) (2017)
- [Kvasir-SEG: A Segmented Polyp Dataset](https://mlsanity.com/paper/1911.07069/) (2019)
- [StackGAN: Text to Photo-realistic Image Synthesis with Stacked Generative Adversarial Networks](https://mlsanity.com/paper/1612.03242/) (2016)
- [CutPaste: Self-Supervised Learning for Anomaly Detection and Localization](https://mlsanity.com/paper/2104.04015/) (2021)
- [DRAEM -- A discriminatively trained reconstruction embedding for surface anomaly detection](https://mlsanity.com/paper/2108.07610/) (2021)
- [PraNet: Parallel Reverse Attention Network for Polyp Segmentation](https://mlsanity.com/paper/2006.11392/) (2020)
- [Anomaly Detection via Reverse Distillation from One-Class Embedding](https://mlsanity.com/paper/2201.10703/) (2022)
- [ELITE: Encoding Visual Concepts into Textual Embeddings for Customized Text-to-Image Generation](https://mlsanity.com/paper/2302.13848/) (2023)
- [AnomalyCLIP: Object-agnostic Prompt Learning for Zero-shot Anomaly Detection](https://mlsanity.com/paper/2310.18961/) (2023)
- [A Unified Model for Multi-class Anomaly Detection](https://mlsanity.com/paper/2206.03687/) (2022)
- [SimpleNet: A Simple Network for Image Anomaly Detection and Localization](https://mlsanity.com/paper/2303.15140/) (2023)
- [A Benchmark for Endoluminal Scene Segmentation of Colonoscopy Images](https://mlsanity.com/paper/1612.00799/) (2016)
- [Few-shot Image Generation via Cross-domain Correspondence](https://mlsanity.com/paper/2104.06820/) (2021)
- [Polyp-PVT: Polyp Segmentation with Pyramid Vision Transformers](https://mlsanity.com/paper/2108.06932/) (2021)
- [Real-IAD: A Real-World Multi-View Dataset for Benchmarking Versatile Industrial Anomaly Detection](https://mlsanity.com/paper/2403.12580/) (2024)
- [Meta-Sim: Learning to Generate Synthetic Datasets](https://mlsanity.com/paper/1904.11621/) (2019)
- [Self-Ensembling with GAN-based Data Augmentation for Domain Adaptation in Semantic Segmentation](https://mlsanity.com/paper/1909.00589/) (2019)
- [DatasetDM: Synthesizing Data with Perception Annotations Using Diffusion Models](https://mlsanity.com/paper/2308.06160/) (2023)

## Abstract (arXiv)

The scarcity of data in various scenarios, such as medical, industry and autonomous driving, leads to model overfitting and dataset imbalance, thus hindering effective detection and segmentation performance. Existing studies employ the generative models to synthesize more training samples to mitigate data scarcity. However, these synthetic samples are repetitive or simplistic and fail to provide "crucial information" that targets the downstream model's weaknesses. Additionally, these methods typically require separate training for different objects, leading to computational inefficiencies. To address these issues, we propose Crucial-Diff, a domain-agnostic framework designed to synthesize crucial samples. Our method integrates two key modules. The Scene Agnostic Feature Extractor (SAFE) utilizes a unified feature extractor to capture target information. The Weakness Aware Sample Miner (WASM) generates hard-to-detect samples using feedback from the detection results of downstream model, which is then fused with the output of SAFE module. Together, our Crucial-Diff framework generates diverse, high-quality training data, achieving a pixel-level AP of 83.63% and an F1-MAX of 78.12% on MVTec. On polyp dataset, Crucial-Diff reaches an mIoU of 81.64% and an mDice of 87.69%. Code is publicly available at https://github.com/JJessicaYao/Crucial-diff.