# PWD: Prior-Guided and Wavelet-Enhanced Diffusion Model for Limited-Angle CT

arXiv: https://arxiv.org/abs/2507.05317 · HTML: https://mlsanity.com/paper/2507.05317/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models.
- Builds on 21 of its 40 references that are in the map.
- First posted on arXiv 30 Jun 2025.

## Placed in

- Diffusion models / [Medical imaging and segmentation](https://mlsanity.com/diffusion/medical-imaging-and-segmentation/)

## Builds on (most cited first, 21 of 21)

- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [Denoising Diffusion Implicit Models](https://mlsanity.com/paper/2010.02502/) (2020)
- [Score-Based Generative Modeling through Stochastic Differential Equations](https://mlsanity.com/paper/2011.13456/) (2020)
- [Scalable Diffusion Models with Transformers](https://mlsanity.com/paper/2212.09748/) (2022)
- [Diffusion Posterior Sampling for General Noisy Inverse Problems](https://mlsanity.com/paper/2209.14687/) (2022)
- [On Distillation of Guided Diffusion Models](https://mlsanity.com/paper/2210.03142/) (2022)
- [Tackling the Generative Learning Trilemma with Denoising Diffusion GANs](https://mlsanity.com/paper/2112.07804/) (2021)
- [Deep Convolutional Neural Network for Inverse Problems in Imaging](https://mlsanity.com/paper/1611.03679/) (2016)
- [A Survey on Generative Diffusion Model](https://mlsanity.com/paper/2209.02646/) (2022)
- [Low Dose CT Image Denoising Using a Generative Adversarial Network with Wasserstein Distance and Perceptual Loss](https://mlsanity.com/paper/1708.00961/) (2017)
- [Diffusion Probabilistic Model Made Slim](https://mlsanity.com/paper/2211.17106/) (2022)
- [DOLCE: A Model-Based Probabilistic Diffusion Framework for Limited-Angle CT Reconstruction](https://mlsanity.com/paper/2211.12340/) (2022)
- [Efficient Diffusion Models: A Survey](https://mlsanity.com/paper/2502.06805/) (2025)
- [Fast-DDPM: Fast Denoising Diffusion Probabilistic Models for Medical Image-to-Image Generation](https://mlsanity.com/paper/2405.14802/) (2024)
- [Lose The Views: Limited Angle CT Reconstruction via Implicit Sinogram Completion](https://mlsanity.com/paper/1711.10388/) (2017)
- [Continual Learning of Diffusion Models with Generative Distillation](https://mlsanity.com/paper/2311.14028/) (2023)
- [DPER: Diffusion Prior Driven Neural Representation for Limited Angle and Sparse View CT Reconstruction](https://mlsanity.com/paper/2404.17890/) (2024)
- [Fast Controllable Diffusion Models for Undersampled MRI Reconstruction](https://mlsanity.com/paper/2311.12078/) (2023)
- [Diffusion Model Quantization: A Review](https://mlsanity.com/paper/2505.05215/) (2025)
- [Spectral2Spectral: Image-spectral Similarity Assisted Spectral CT Deep Reconstruction without Reference](https://mlsanity.com/paper/2210.01125/) (2022)
- [Limited-Angle Tomography Reconstruction via Deep End-To-End Learning on Synthetic Data](https://mlsanity.com/paper/2309.06948/) (2023)

## Built on by (most cited first, 1 of 1)

- [Limited-Angle Tomography Reconstruction via Projector Guided 3D Diffusion](https://mlsanity.com/paper/2510.06516/) (2025)

## Abstract (arXiv)

Generative diffusion models have received increasing attention in medical imaging, particularly in limited-angle computed tomography (LACT). Standard diffusion models achieve high-quality image reconstruction but require a large number of sampling steps during inference, resulting in substantial computational overhead. Although skip-sampling strategies have been proposed to improve efficiency, they often lead to loss of fine structural details. To address this issue, we propose a prior information embedding and wavelet feature fusion fast sampling diffusion model for LACT reconstruction. The PWD enables efficient sampling while preserving reconstruction fidelity in LACT, and effectively mitigates the degradation typically introduced by skip-sampling. Specifically, during the training phase, PWD maps the distribution of LACT images to that of fully sampled target images, enabling the model to learn structural correspondences between them. During inference, the LACT image serves as an explicit prior to guide the sampling trajectory, allowing for high-quality reconstruction with significantly fewer steps. In addition, PWD performs multi-scale feature fusion in the wavelet domain, effectively enhancing the reconstruction of fine details by leveraging both low-frequency and high-frequency information. Quantitative and qualitative evaluations on clinical dental arch CBCT and periapical datasets demonstrate that PWD outperforms existing methods under the same sampling condition. Using only 50 sampling steps, PWD achieves at least 1.7 dB improvement in PSNR and 10% gain in SSIM.
