# DoPI: Doctor-like Proactive Interrogation LLM for Traditional Chinese Medicine

arXiv: https://arxiv.org/abs/2507.04877 · HTML: https://mlsanity.com/paper/2507.04877/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 19 of its 27 references that are in the map.
- First posted on arXiv 7 Jul 2025.

## Builds on (most cited first, 19 of 19)

- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [LLaMA: Open and Efficient Foundation Language Models](https://mlsanity.com/paper/2302.13971/) (2023)
- [Semi-Supervised Classification with Graph Convolutional Networks](https://mlsanity.com/paper/1609.02907/) (2016)
- [Judging LLM-as-a-Judge with MT-Bench and Chatbot Arena](https://mlsanity.com/paper/2306.05685/) (2023)
- [BLOOM: A 176B-Parameter Open-Access Multilingual Language Model](https://mlsanity.com/paper/2211.05100/) (2022)
- [ChatDoctor: A Medical Chat Model Fine-Tuned on a Large Language Model Meta-AI (LLaMA) Using Medical Domain Knowledge](https://mlsanity.com/paper/2303.14070/) (2023)
- [Efficient and Effective Text Encoding for Chinese LLaMA and Alpaca](https://mlsanity.com/paper/2304.08177/) (2023)
- [MedAlpaca -- An Open-Source Collection of Medical Conversational AI Models and Training Data](https://mlsanity.com/paper/2304.08247/) (2023)
- [HuatuoGPT, towards Taming Language Model to Be a Doctor](https://mlsanity.com/paper/2305.15075/) (2023)
- [Evaluation of OpenAI o1: Opportunities and Challenges of AGI](https://mlsanity.com/paper/2409.18486/) (2024)
- [Zhongjing: Enhancing the Chinese Medical Capabilities of Large Language Model through Expert Feedback and Real-world Multi-turn Dialogue](https://mlsanity.com/paper/2308.03549/) (2023)
- [In-Edge AI: Intelligentizing Mobile Edge Computing, Caching and Communication by Federated Learning](https://mlsanity.com/paper/1809.07857/) (2018)
- [BianQue: Balancing the Questioning and Suggestion Ability of Health LLMs with Multi-turn Health Conversations Polished by ChatGPT](https://mlsanity.com/paper/2310.15896/) (2023)
- [Qibo: A Large Language Model for Traditional Chinese Medicine](https://mlsanity.com/paper/2403.16056/) (2024)
- [OpenTCM: A GraphRAG-Empowered LLM-based System for Traditional Chinese Medicine Knowledge Retrieval and Diagnosis](https://mlsanity.com/paper/2504.20118/) (2025)
- [MedChatZH: a Better Medical Adviser Learns from Better Instructions](https://mlsanity.com/paper/2309.01114/) (2023)
- [TCM-GPT: Efficient Pre-training of Large Language Models for Domain Adaptation in Traditional Chinese Medicine](https://mlsanity.com/paper/2311.01786/) (2023)

## Built on by (most cited first, 1 of 1)

- [SteerVTE: Seamless Video Text Editing with Style and Glyph Control](https://mlsanity.com/paper/2606.23254/) (2026)

## Abstract (arXiv)

Enhancing interrogation capabilities in Traditional Chinese Medicine (TCM) diagnosis through multi-turn dialogues and knowledge graphs presents a significant challenge for modern AI systems. Current large language models (LLMs), despite their advancements, exhibit notable limitations in medical applications, particularly in conducting effective multi-turn dialogues and proactive questioning. These shortcomings hinder their practical application and effectiveness in simulating real-world diagnostic scenarios. To address these limitations, we propose DoPI, a novel LLM system specifically designed for the TCM domain. The DoPI system introduces a collaborative architecture comprising a guidance model and an expert model. The guidance model conducts multi-turn dialogues with patients and dynamically generates questions based on a knowledge graph to efficiently extract critical symptom information. Simultaneously, the expert model leverages deep TCM expertise to provide final diagnoses and treatment plans. Furthermore, this study constructs a multi-turn doctor-patient dialogue dataset to simulate realistic consultation scenarios and proposes a novel evaluation methodology that does not rely on manually collected real-world consultation data. Experimental results show that the DoPI system achieves an accuracy rate of 84.68 percent in interrogation outcomes, significantly enhancing the model's communication ability during diagnosis while maintaining professional expertise.