# Single Image Test-Time Adaptation via Multi-View Co-Training

arXiv: https://arxiv.org/abs/2506.23705 · HTML: https://mlsanity.com/paper/2506.23705/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Builds on 15 of its 30 references that are in the map.
- First posted on arXiv 30 Jun 2025.

## Builds on (most cited first, 15 of 15)

- [Do We Really Need to Access the Source Data? Source Hypothesis Transfer for Unsupervised Domain Adaptation](https://mlsanity.com/paper/2002.08546/) (2020)
- [Improving robustness against common corruptions by covariate shift adaptation](https://mlsanity.com/paper/2006.16971/) (2020)
- [Towards Stable Test-Time Adaptation in Dynamic Wild World](https://mlsanity.com/paper/2302.12400/) (2023)
- [MEMO: Test Time Robustness via Adaptation and Augmentation](https://mlsanity.com/paper/2110.09506/) (2021)
- [A Comprehensive Survey on Test-Time Adaptation under Distribution Shifts](https://mlsanity.com/paper/2303.15361/) (2023)
- [Evaluating Prediction-Time Batch Normalization for Robustness under Covariate Shift](https://mlsanity.com/paper/2006.10963/) (2020)
- [Metrics reloaded: Recommendations for image analysis validation](https://mlsanity.com/paper/2206.01653/) (2022)
- [CrossMoDA 2021 challenge: Benchmark of Cross-Modality Domain Adaptation techniques for Vestibular Schwannoma and Cochlea Segmentation](https://mlsanity.com/paper/2201.02831/) (2022)
- [A large-scale multicenter breast cancer DCE-MRI benchmark dataset with expert segmentations](https://mlsanity.com/paper/2406.13844/) (2024)
- [SwinMM: Masked Multi-view with Swin Transformers for 3D Medical Image Segmentation](https://mlsanity.com/paper/2307.12591/) (2023)
- [TTTFlow: Unsupervised Test-Time Training with Normalizing Flow](https://mlsanity.com/paper/2210.11389/) (2022)
- [Test time Adaptation through Perturbation Robustness](https://mlsanity.com/paper/2110.10232/) (2021)
- [Test-Time Adaptation with Shape Moments for Image Segmentation](https://mlsanity.com/paper/2205.07983/) (2022)
- [Medical Image Segmentation with InTEnt: Integrated Entropy Weighting for Single Image Test-Time Adaptation](https://mlsanity.com/paper/2402.09604/) (2024)
- [Incremental Cross-view Mutual Distillation for Self-supervised Medical CT Synthesis](https://mlsanity.com/paper/2112.10325/) (2021)

## Built on by (most cited first, 3 of 3)

- [The MAMA-MIA Challenge: Advancing Generalizability and Fairness in Breast MRI Tumor Segmentation and Treatment Response Prediction](https://mlsanity.com/paper/2603.01250/) (2026)
- [Mask-Guided Multi-Channel SwinUNETR Framework for Robust MRI Classification](https://mlsanity.com/paper/2508.20621/) (2025)
- [VISTA: Variance-Gated Inter-Sequence Test-Time Adaptation for Multi-Sequence MRI Segmentation](https://mlsanity.com/paper/2605.17433/) (2026)

## Abstract (arXiv)

Test-time adaptation enables a trained model to adjust to a new domain during inference, making it particularly valuable in clinical settings where such on-the-fly adaptation is required. However, existing techniques depend on large target domain datasets, which are often impractical and unavailable in medical scenarios that demand per-patient, real-time inference. Moreover, current methods commonly focus on two-dimensional images, failing to leverage the volumetric richness of medical imaging data. Bridging this gap, we propose a Patch-Based Multi-View Co-Training method for Single Image Test-Time adaptation. Our method enforces feature and prediction consistency through uncertainty-guided self-training, enabling effective volumetric segmentation in the target domain with only a single test-time image. Validated on three publicly available breast magnetic resonance imaging datasets for tumor segmentation, our method achieves performance close to the upper bound supervised benchmark while also outperforming all existing state-of-the-art methods, on average by a Dice Similarity Coefficient of 3.75%. We publicly share our accessible codebase, readily integrable with the popular nnUNet framework, at https://github.com/smriti-joshi/muvi.git.