# Robust Deep Learning for Myocardial Scar Segmentation in Cardiac MRI with Noisy Labels

arXiv: https://arxiv.org/abs/2506.21151 · HTML: https://mlsanity.com/paper/2506.21151/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Builds on 6 of its 27 references that are in the map.
- First posted on arXiv 26 Jun 2025.

## Builds on (most cited first, 6 of 6)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [Encoder-Decoder with Atrous Separable Convolution for Semantic Image Segmentation](https://mlsanity.com/paper/1802.02611/) (2018)
- [YOLOv12: Attention-Centric Real-Time Object Detectors](https://mlsanity.com/paper/2502.12524/) (2025)
- [Deep learning for cardiac image segmentation: A review](https://mlsanity.com/paper/1911.03723/) (2019)
- [Deep Learning methods for automatic evaluation of delayed enhancement-MRI. The results of the EMIDEC challenge](https://mlsanity.com/paper/2108.04016/) (2021)

## Built on by (most cited first, 3 of 3)

- [Curriculum-Guided Myocardial Scar Segmentation for Ischemic and Non-ischemic Cardiomyopathy](https://mlsanity.com/paper/2603.28560/) (2026)
- [Progressive Learning with Anatomical Priors for Reliable Left Atrial Scar Segmentation from Late Gadolinium Enhancement MRI](https://mlsanity.com/paper/2603.26186/) (2026)
- [CalcSeg: Confidence-aware 3D Latent Context Curriculum Learning For Myocardial Scar Segmentation From Single-Stack LGE-CMRs](https://mlsanity.com/paper/2608.20305/) (2026)

## Abstract (arXiv)

The accurate segmentation of myocardial scars from cardiac MRI is essential for clinical assessment and treatment planning. In this study, we propose a robust deep-learning pipeline for fully automated myocardial scar detection and segmentation by fine-tuning state-of-the-art models. The method explicitly addresses challenges of label noise from semi-automatic annotations, data heterogeneity, and class imbalance through the use of Kullback-Leibler loss and extensive data augmentation. We evaluate the model's performance on both acute and chronic cases and demonstrate its ability to produce accurate and smooth segmentations despite noisy labels. In particular, our approach outperforms state-of-the-art models like nnU-Net and shows strong generalizability in an out-of-distribution test set, highlighting its robustness across various imaging conditions and clinical tasks. These results establish a reliable foundation for automated myocardial scar quantification and support the broader clinical adoption of deep learning in cardiac imaging.