# Enabling On-Device Medical AI Assistants via Input-Driven Saliency Adaptation

arXiv: https://arxiv.org/abs/2506.11105 · HTML: https://mlsanity.com/paper/2506.11105/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 15 of its 24 references that are in the map.
- First posted on arXiv 7 Jun 2025.

## Builds on (most cited first, 15 of 15)

- [The Llama 3 Herd of Models](https://mlsanity.com/paper/2407.21783/) (2024)
- [Large Language Models Encode Clinical Knowledge](https://mlsanity.com/paper/2212.13138/) (2022)
- [What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Exams](https://mlsanity.com/paper/2009.13081/) (2020)
- [PubMedQA: A Dataset for Biomedical Research Question Answering](https://mlsanity.com/paper/1909.06146/) (2019)
- [Gemma: Open Models Based on Gemini Research and Technology](https://mlsanity.com/paper/2403.08295/) (2024)
- [LLM-Pruner: On the Structural Pruning of Large Language Models](https://mlsanity.com/paper/2305.11627/) (2023)
- [BioGPT: Generative Pre-trained Transformer for Biomedical Text Generation and Mining](https://mlsanity.com/paper/2210.10341/) (2022)
- [SliceGPT: Compress Large Language Models by Deleting Rows and Columns](https://mlsanity.com/paper/2401.15024/) (2024)
- [MedAlpaca -- An Open-Source Collection of Medical Conversational AI Models and Training Data](https://mlsanity.com/paper/2304.08247/) (2023)
- [Survey of the State of the Art in Natural Language Generation: Core tasks, applications and evaluation](https://mlsanity.com/paper/1703.09902/) (2017)
- [A Question-Entailment Approach to Question Answering](https://mlsanity.com/paper/1901.08079/) (2019)
- [A Comprehensive Survey on Process-Oriented Automatic Text Summarization with Exploration of LLM-Based Methods](https://mlsanity.com/paper/2403.02901/) (2024)
- [Natural Language Reasoning, A Survey](https://mlsanity.com/paper/2303.14725/) (2023)
- [Multi-RAG: A Multimodal Retrieval-Augmented Generation System for Adaptive Video Understanding](https://mlsanity.com/paper/2505.23990/) (2025)
- [ChatSim: Underwater Simulation with Natural Language Prompting](https://mlsanity.com/paper/2308.04029/) (2023)

## Built on by (most cited first, 2 of 2)

- [DREAM: Domain-aware Reasoning for Efficient Autonomous Underwater Monitoring](https://mlsanity.com/paper/2509.13666/) (2025)
- [SatReg: Regression-based Neural Architecture Search for Lightweight Satellite Image Segmentation](https://mlsanity.com/paper/2604.10306/) (2026)

## Abstract (arXiv)

Large Language Models (LLMs) have significant impact on the healthcare scenarios but remain prohibitively large for deployment in real-time, resource-constrained environments such as edge devices. In this work, we introduce a novel medical assistant system, optimized through our general-purpose compression framework, which tailors Large Language Models (LLMs) for deployment in specialized domains. By measuring neuron saliency on domain-specific data, our method can aggressively prune irrelevant neurons, reducing model size while preserving performance. Following pruning, we apply post-training quantization to further reduce the memory footprint, and evaluate the compressed model across medical benchmarks including MedMCQA, MedQA, and PubMedQA. We also deploy the 50% compressed Gemma and the 67% compressed LLaMA3 models on Jetson Orin Nano (18.7W peak) and Raspberry Pi 5 (6.3W peak), achieving real-time, energy-efficient inference under hardware constraints.