# Time-Lapse Video-Based Embryo Grading via Complementary Spatial-Temporal Pattern Mining

arXiv: https://arxiv.org/abs/2506.04950 · HTML: https://mlsanity.com/paper/2506.04950/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 10 of its 27 references that are in the map.
- First posted on arXiv 5 Jun 2025.

## Builds on (most cited first, 10 of 10)

- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [End-to-End Object Detection with Transformers](https://mlsanity.com/paper/2005.12872/) (2020)
- [Parameter-Efficient Transfer Learning for NLP](https://mlsanity.com/paper/1902.00751/) (2019)
- [Switch Transformers: Scaling to Trillion Parameter Models with Simple and Efficient Sparsity](https://mlsanity.com/paper/2101.03961/) (2021)
- [SlowFast Networks for Video Recognition](https://mlsanity.com/paper/1812.03982/) (2018)
- [ViViT: A Video Vision Transformer](https://mlsanity.com/paper/2103.15691/) (2021)
- [Can Spatiotemporal 3D CNNs Retrace the History of 2D CNNs and ImageNet?](https://mlsanity.com/paper/1711.09577/) (2017)
- [AIM: Adapting Image Models for Efficient Video Action Recognition](https://mlsanity.com/paper/2302.03024/) (2023)
- [EmbryosFormer: Deformable Transformer and Collaborative Encoding-Decoding for Embryos Stage Development Classification](https://mlsanity.com/paper/2210.04615/) (2022)
- [Multimodal Learning for Embryo Viability Prediction in Clinical IVF](https://mlsanity.com/paper/2410.15581/) (2024)

## Abstract (arXiv)

Artificial intelligence has recently shown promise in automated embryo selection for In-Vitro Fertilization (IVF). However, current approaches either address partial embryo evaluation lacking holistic quality assessment or target clinical outcomes inevitably confounded by extra-embryonic factors, both limiting clinical utility. To bridge this gap, we propose a new task called Video-Based Embryo Grading - the first paradigm that directly utilizes full-length time-lapse monitoring (TLM) videos to predict embryologists' overall quality assessments. To support this task, we curate a real-world clinical dataset comprising over 2,500 TLM videos, each annotated with a grading label indicating the overall quality of embryos. Grounded in clinical decision-making principles, we propose a Complementary Spatial-Temporal Pattern Mining (CoSTeM) framework that conceptually replicates embryologists' evaluation process. The CoSTeM comprises two branches: (1) a morphological branch using a Mixture of Cross-Attentive Experts layer and a Temporal Selection Block to select discriminative local structural features, and (2) a morphokinetic branch employing a Temporal Transformer to model global developmental trajectories, synergistically integrating static and dynamic determinants for grading embryos. Extensive experimental results demonstrate the superiority of our design. This work provides a valuable methodological framework for AI-assisted embryo selection. The dataset and source code will be publicly available upon acceptance.