# Large Language Models for Depression Recognition in Spoken Language Integrating Psychological Knowledge

arXiv: https://arxiv.org/abs/2505.22863 · HTML: https://mlsanity.com/paper/2505.22863/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Builds on 17 of its 44 references that are in the map.
- First posted on arXiv 28 May 2025.

## Builds on (most cited first, 17 of 17)

- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [LLaMA: Open and Efficient Foundation Language Models](https://mlsanity.com/paper/2302.13971/) (2023)
- [Evaluating Large Language Models Trained on Code](https://mlsanity.com/paper/2107.03374/) (2021)
- [Robust Speech Recognition via Large-Scale Weak Supervision](https://mlsanity.com/paper/2212.04356/) (2022)
- [wav2vec 2.0: A Framework for Self-Supervised Learning of Speech Representations](https://mlsanity.com/paper/2006.11477/) (2020)
- [SALMONN: Towards Generic Hearing Abilities for Large Language Models](https://mlsanity.com/paper/2310.13289/) (2023)
- [AVEC 2019 Workshop and Challenge: State-of-Mind, Detecting Depression with AI, and Cross-Cultural Affect Recognition](https://mlsanity.com/paper/1907.11510/) (2019)
- [AVEC 2016 - Depression, Mood, and Emotion Recognition Workshop and Challenge](https://mlsanity.com/paper/1605.01600/) (2016)
- [EmoLLMs: A Series of Emotional Large Language Models and Annotation Tools for Comprehensive Affective Analysis](https://mlsanity.com/paper/2401.08508/) (2024)
- [Depression Detection on Social Media with Large Language Models](https://mlsanity.com/paper/2403.10750/) (2024)
- [Refashioning Emotion Recognition Modelling: The Advent of Generalised Large Models](https://mlsanity.com/paper/2308.11578/) (2023)
- [Affective Computing Has Changed: The Foundation Model Disruption](https://mlsanity.com/paper/2409.08907/) (2024)
- [Depression Detection and Analysis using Large Language Models on Textual and Audio-Visual Modalities](https://mlsanity.com/paper/2407.06125/) (2024)
- [Neuroplasticity in Artificial Intelligence -- An Overview and Inspirations on Drop In & Out Learning](https://mlsanity.com/paper/2503.21419/) (2025)
- [PsychoLex: Unveiling the Psychological Mind of Large Language Models](https://mlsanity.com/paper/2408.08848/) (2024)
- [Sentiment Informed Sentence BERT-Ensemble Algorithm for Depression Detection](https://mlsanity.com/paper/2409.13713/) (2024)
- [Depression Diagnosis and Forecast based on Mobile Phone Sensor Data](https://mlsanity.com/paper/2205.07861/) (2022)

## Built on by (most cited first, 3 of 3)

- [Dep-LLM: Training-Free Depression Diagnosis via Evidence-Guided Structured Multi-factor with Reliable LLM Reasoning](https://mlsanity.com/paper/2606.10796/) (2026)
- [Explainable Speech Emotion Recognition: Weighted Attribute Fairness to Model Demographic Contributions to Social Bias](https://mlsanity.com/paper/2604.19763/) (2026)
- [Predicting Psychological Well-Being from Spontaneous Speech using LLMs](https://mlsanity.com/paper/2605.11303/) (2026)

## Abstract (arXiv)

Depression is a growing concern gaining attention in both public discourse and AI research. While deep neural networks (DNNs) have been used for recognition, they still lack real-world effectiveness. Large language models (LLMs) show strong potential but require domain-specific fine-tuning and struggle with non-textual cues. Since depression is often expressed through vocal tone and behaviour rather than explicit text, relying on language alone is insufficient. Diagnostic accuracy also suffers without incorporating psychological expertise. To address these limitations, we present, to the best of our knowledge, the first application of LLMs to multimodal depression detection using the DAIC-WOZ dataset. We extract the audio features using the pre-trained model Wav2Vec, and mapped it to text-based LLMs for further processing. We also propose a novel strategy for incorporating psychological knowledge into LLMs to enhance diagnostic performance, specifically using a question and answer set to grant authorised knowledge to LLMs. Our approach yields a notable improvement in both Mean Absolute Error (MAE) and Root Mean Square Error (RMSE) compared to a base score proposed by the related original paper. The codes are available at https://github.com/myxp-lyp/Depression-detection.git
