# Knowledge Distillation Approach for SOS Fusion Staging: Towards Fully Automated Skeletal Maturity Assessment

arXiv: https://arxiv.org/abs/2505.21561 · HTML: https://mlsanity.com/paper/2505.21561/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Distillation for medical imaging, one of 12 directions in Knowledge distillation.
- Builds on 6 of its 41 references that are in the map.
- First posted on arXiv 27 May 2025.

## Placed in

- Knowledge distillation / [Distillation for medical imaging](https://mlsanity.com/distill/distillation-for-medical-imaging/)

## Builds on (most cited first, 6 of 6)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Distilling the Knowledge in a Neural Network](https://mlsanity.com/paper/1503.02531/) (2015)
- [Grad-CAM: Visual Explanations from Deep Networks via Gradient-based Localization](https://mlsanity.com/paper/1610.02391/) (2016)
- [EfficientNet: Rethinking Model Scaling for Convolutional Neural Networks](https://mlsanity.com/paper/1905.11946/) (2019)
- [A ConvNet for the 2020s](https://mlsanity.com/paper/2201.03545/) (2022)

## Abstract (arXiv)

We introduce a novel deep learning framework for the automated staging of spheno-occipital synchondrosis (SOS) fusion, a critical diagnostic marker in both orthodontics and forensic anthropology. Our approach leverages a dual-model architecture wherein a teacher model, trained on manually cropped images, transfers its precise spatial understanding to a student model that operates on full, uncropped images. This knowledge distillation is facilitated by a newly formulated loss function that aligns spatial logits as well as incorporates gradient-based attention spatial mapping, ensuring that the student model internalizes the anatomically relevant features without relying on external cropping or YOLO-based segmentation. By leveraging expert-curated data and feedback at each step, our framework attains robust diagnostic accuracy, culminating in a clinically viable end-to-end pipeline. This streamlined approach obviates the need for additional pre-processing tools and accelerates deployment, thereby enhancing both the efficiency and consistency of skeletal maturation assessment in diverse clinical settings.