# Agentic publications: redesigning scientific publishing in the age of thinking large language models

arXiv: https://arxiv.org/abs/2505.13246 · HTML: https://mlsanity.com/paper/2505.13246/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Knowledge- and tool-augmented reasoning, one of 17 directions in LLM reasoning.
- Builds on 3 of its 42 references that are in the map.
- First posted on arXiv 19 May 2025.

## Placed in

- LLM reasoning / [Knowledge- and tool-augmented reasoning](https://mlsanity.com/lr/knowledge-and-tool-augmented-reasoning/)
- LLM agents and tool use / [Web, search, and research agents](https://mlsanity.com/agents/web-search-and-research-agents/)

## Builds on (most cited first, 3 of 3)

- [Growth rates of modern science: A latent piecewise growth curve approach to model publication numbers from established and new literature databases](https://mlsanity.com/paper/2012.07675/) (2020)
- [A Survey on Knowledge-Oriented Retrieval-Augmented Generation](https://mlsanity.com/paper/2503.10677/) (2025)
- [Nanopublication-Based Semantic Publishing and Reviewing: A Field Study with Formalization Papers](https://mlsanity.com/paper/2203.01608/) (2022)

## Abstract (arXiv)

Purpose: This paper introduces the concept of "Agentic Publication," a novel LLM-driven framework designed to complement traditional scientific publishing by transforming papers into interactive knowledge systems that address challenges created by exponential growth in scientific literature. Design/methodology/approach: Our architecture integrates structured data (knowledge graphs, metadata) with unstructured content (text, multimedia) through retrieval-augmented generation and multi-agent verification. The system provides interfaces for humans and artificial agents, offering narrative explanations alongside machine-readable outputs. Implementation leverages vector databases for semantic search, knowledge graphs for structured reasoning, and collaborative verification agents. Findings: Our proof-of-concept demonstration showcases multilingual interaction, API accessibility, continuous knowledge flow, and structured knowledge representation. The framework enables dynamic updating of knowledge, synthesis of new findings, and customizable detail levels. Originality: The Agentic Publication represents a transformative approach to scientific communication by creating responsive knowledge synthesis systems while maintaining scientific rigor. Integrating multi-agent verification with traditional publishing pathways creates a more efficient, accessible, and collaborative research ecosystem, particularly valuable in interdisciplinary fields. Practical implications: The system is a powerful companion for researchers navigating complex knowledge landscapes, offering tailored information access across disciplines while addressing ethical considerations through automated validation, expert oversight, and transparent governance.