# GAP: Graph-Assisted Prompts for Dialogue-based Medication Recommendation

arXiv: https://arxiv.org/abs/2505.12888 · HTML: https://mlsanity.com/paper/2505.12888/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 32 of its 47 references that are in the map.
- First posted on arXiv 19 May 2025.

## Builds on (most cited first, 30 of 32)

- [Chain-of-Thought Prompting Elicits Reasoning in Large Language Models](https://mlsanity.com/paper/2201.11903/) (2022)
- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [Retrieval-Augmented Generation for Large Language Models: A Survey](https://mlsanity.com/paper/2312.10997/) (2023)
- [Mixtral of Experts](https://mlsanity.com/paper/2401.04088/) (2024)
- [Measuring and Narrowing the Compositionality Gap in Language Models](https://mlsanity.com/paper/2210.03350/) (2022)
- [Large Language Models Struggle to Learn Long-Tail Knowledge](https://mlsanity.com/paper/2211.08411/) (2022)
- [Making Retrieval-Augmented Language Models Robust to Irrelevant Context](https://mlsanity.com/paper/2310.01558/) (2023)
- [A Comprehensive Survey of Hallucination Mitigation Techniques in Large Language Models](https://mlsanity.com/paper/2401.01313/) (2024)
- [RECOMP: Improving Retrieval-Augmented LMs with Compression and Selective Augmentation](https://mlsanity.com/paper/2310.04408/) (2023)
- [ChatIE: Zero-Shot Information Extraction via Chatting with ChatGPT](https://mlsanity.com/paper/2302.10205/) (2023)
- [HuatuoGPT, towards Taming Language Model to Be a Doctor](https://mlsanity.com/paper/2305.15075/) (2023)
- [A Survey of Large Language Models for Healthcare: from Data, Technology, and Applications to Accountability and Ethics](https://mlsanity.com/paper/2310.05694/) (2023)
- [MedDialog: Two Large-scale Medical Dialogue Datasets](https://mlsanity.com/paper/2004.03329/) (2020)
- [Take a Step Back: Evoking Reasoning via Abstraction in Large Language Models](https://mlsanity.com/paper/2310.06117/) (2023)
- [DoctorGLM: Fine-tuning your Chinese Doctor is not a Herculean Task](https://mlsanity.com/paper/2304.01097/) (2023)
- [ChatCAD: Interactive Computer-Aided Diagnosis on Medical Image using Large Language Models](https://mlsanity.com/paper/2302.07257/) (2023)
- [DISC-MedLLM: Bridging General Large Language Models and Real-World Medical Consultation](https://mlsanity.com/paper/2308.14346/) (2023)
- [ClinicalGPT: Large Language Models Finetuned with Diverse Medical Data and Comprehensive Evaluation](https://mlsanity.com/paper/2306.09968/) (2023)
- [GAMENet: Graph Augmented MEmory Networks for Recommending Medication Combination](https://mlsanity.com/paper/1809.01852/) (2018)
- [DialogXL: All-in-One XLNet for Multi-Party Conversation Emotion Recognition](https://mlsanity.com/paper/2012.08695/) (2020)
- [Large Language Models Know Your Contextual Search Intent: A Prompting Framework for Conversational Search](https://mlsanity.com/paper/2303.06573/) (2023)
- [BianQue: Balancing the Questioning and Suggestion Ability of Health LLMs with Multi-turn Health Conversations Polished by ChatGPT](https://mlsanity.com/paper/2310.15896/) (2023)
- [Dual Memory Neural Computer for Asynchronous Two-view Sequential Learning](https://mlsanity.com/paper/1802.00662/) (2018)
- [Can Large Language Models Understand Context?](https://mlsanity.com/paper/2402.00858/) (2024)
- [Large Language Model Distilling Medication Recommendation Model](https://mlsanity.com/paper/2402.02803/) (2024)
- [Leveraging Large Language Model as Simulated Patients for Clinical Education](https://mlsanity.com/paper/2404.13066/) (2024)
- [DialMed: A Dataset for Dialogue-based Medication Recommendation](https://mlsanity.com/paper/2203.07094/) (2022)
- [Medical Dialogue Generation via Dual Flow Modeling](https://mlsanity.com/paper/2305.18109/) (2023)
- [Medical Dialogue Response Generation with Pivotal Information Recalling](https://mlsanity.com/paper/2206.08611/) (2022)
- [PlugMed: Improving Specificity in Patient-Centered Medical Dialogue Generation using In-Context Learning](https://mlsanity.com/paper/2305.11508/) (2023)

## Abstract (arXiv)

Medication recommendations have become an important task in the healthcare domain, especially in measuring the accuracy and safety of medical dialogue systems (MDS). Different from the recommendation task based on electronic health records (EHRs), dialogue-based medication recommendations require research on the interaction details between patients and doctors, which is crucial but may not exist in EHRs. Recent advancements in large language models (LLM) have extended the medical dialogue domain. These LLMs can interpret patients' intent and provide medical suggestions including medication recommendations, but some challenges are still worth attention. During a multi-turn dialogue, LLMs may ignore the fine-grained medical information or connections across the dialogue turns, which is vital for providing accurate suggestions. Besides, LLMs may generate non-factual responses when there is a lack of domain-specific knowledge, which is more risky in the medical domain. To address these challenges, we propose a Graph-Assisted Prompts (GAP) framework for dialogue-based medication recommendation. It extracts medical concepts and corresponding states from dialogue to construct an explicitly patient-centric graph, which can describe the neglected but important information. Further, combined with external medical knowledge graphs, GAP can generate abundant queries and prompts, thus retrieving information from multiple sources to reduce the non-factual responses. We evaluate GAP on a dialogue-based medication recommendation dataset and further explore its potential in a more difficult scenario, dynamically diagnostic interviewing. Extensive experiments demonstrate its competitive performance when compared with strong baselines.