# Ordered-subsets Multi-diffusion Model for Sparse-view CT Reconstruction

arXiv: https://arxiv.org/abs/2505.09985 · HTML: https://mlsanity.com/paper/2505.09985/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models.
- Builds on 13 of its 29 references that are in the map.
- First posted on arXiv 15 May 2025.

## Placed in

- Diffusion models / [Medical imaging and segmentation](https://mlsanity.com/diffusion/medical-imaging-and-segmentation/)

## Builds on (most cited first, 13 of 13)

- [Score-Based Generative Modeling through Stochastic Differential Equations](https://mlsanity.com/paper/2011.13456/) (2020)
- [Deep Unsupervised Learning using Nonequilibrium Thermodynamics](https://mlsanity.com/paper/1503.03585/) (2015)
- [Deep Convolutional Neural Network for Inverse Problems in Imaging](https://mlsanity.com/paper/1611.03679/) (2016)
- [Low-Dose CT with a Residual Encoder-Decoder Convolutional Neural Network (RED-CNN)](https://mlsanity.com/paper/1702.00288/) (2017)
- [Deep Generative Learning via Schr"odinger Bridge](https://mlsanity.com/paper/2106.10410/) (2021)
- [Deep-neural-network based sinogram synthesis for sparse-view CT image reconstruction](https://mlsanity.com/paper/1803.00694/) (2018)
- [Maximum Likelihood Training of Implicit Nonlinear Diffusion Models](https://mlsanity.com/paper/2205.13699/) (2022)
- [Generative Modeling in Sinogram Domain for Sparse-view CT Reconstruction](https://mlsanity.com/paper/2211.13926/) (2022)
- [Heavy-tailed denoising score matching](https://mlsanity.com/paper/2112.09788/) (2021)
- [Patch-Based Denoising Diffusion Probabilistic Model for Sparse-View CT Reconstruction](https://mlsanity.com/paper/2211.10388/) (2022)
- [Stage-by-stage Wavelet Optimization Refinement Diffusion Model for Sparse-View CT Reconstruction](https://mlsanity.com/paper/2308.15942/) (2023)
- [DPER: Diffusion Prior Driven Neural Representation for Limited Angle and Sparse View CT Reconstruction](https://mlsanity.com/paper/2404.17890/) (2024)
- [Multi-domain Integrative Swin Transformer network for Sparse-View Tomographic Reconstruction](https://mlsanity.com/paper/2111.14831/) (2021)

## Abstract (arXiv)

Score-based diffusion models have shown significant promise in the field of sparse-view CT reconstruction. However, the projection dataset is large and riddled with redundancy. Consequently, applying the diffusion model to unprocessed data results in lower learning effectiveness and higher learning difficulty, frequently leading to reconstructed images that lack fine details. To address these issues, we propose the ordered-subsets multi-diffusion model (OSMM) for sparse-view CT reconstruction. The OSMM innovatively divides the CT projection data into equal subsets and employs multi-subsets diffusion model (MSDM) to learn from each subset independently. This targeted learning approach reduces complexity and enhances the reconstruction of fine details. Furthermore, the integration of one-whole diffusion model (OWDM) with complete sinogram data acts as a global information constraint, which can reduce the possibility of generating erroneous or inconsistent sinogram information. Moreover, the OSMM's unsupervised learning framework provides strong robustness and generalizability, adapting seamlessly to varying sparsity levels of CT sinograms. This ensures consistent and reliable performance across different clinical scenarios. Experimental results demonstrate that OSMM outperforms traditional diffusion models in terms of image quality and noise resilience, offering a powerful and versatile solution for advanced CT imaging in sparse-view scenarios.