# MoRe-3DGSMR: Motion-resolved reconstruction framework for free-breathing pulmonary MRI based on 3D Gaussian representation

arXiv: https://arxiv.org/abs/2505.04959 · HTML: https://mlsanity.com/paper/2505.04959/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 15 of its 49 references that are in the map.
- First posted on arXiv 8 May 2025.

## Builds on (most cited first, 15 of 15)

- [3D Gaussian Splatting for Real-Time Radiance Field Rendering](https://mlsanity.com/paper/2308.04079/) (2023)
- [Feature Pyramid Networks for Object Detection](https://mlsanity.com/paper/1612.03144/) (2016)
- [Spatial Transformer Networks](https://mlsanity.com/paper/1506.02025/) (2015)
- [pixelSplat: 3D Gaussian Splats from Image Pairs for Scalable Generalizable 3D Reconstruction](https://mlsanity.com/paper/2312.12337/) (2023)
- [Mip-Splatting: Alias-free 3D Gaussian Splatting](https://mlsanity.com/paper/2311.16493/) (2023)
- [Fast and Accurate Image Super-Resolution with Deep Laplacian Pyramid Networks](https://mlsanity.com/paper/1710.01992/) (2017)
- [Multi-Scale 3D Gaussian Splatting for Anti-Aliased Rendering](https://mlsanity.com/paper/2311.17089/) (2023)
- [FreGS: 3D Gaussian Splatting with Progressive Frequency Regularization](https://mlsanity.com/paper/2403.06908/) (2024)
- [R2-Gaussian: Rectifying Radiative Gaussian Splatting for Tomographic Reconstruction](https://mlsanity.com/paper/2405.20693/) (2024)
- [Relaxing Accurate Initialization Constraint for 3D Gaussian Splatting](https://mlsanity.com/paper/2403.09413/) (2024)
- [Extreme MRI: Large-Scale Volumetric Dynamic Imaging from Continuous Non-Gated Acquisitions](https://mlsanity.com/paper/1909.13482/) (2019)
- [Analysis of Deep Image Prior and Exploiting Self-Guidance for Image Reconstruction](https://mlsanity.com/paper/2402.04097/) (2024)
- [Three-Dimensional MRI Reconstruction with Gaussian Representations: Tackling the Undersampling Problem](https://mlsanity.com/paper/2502.06510/) (2025)
- [Iterative Motion Compensation reconstruction ultra-short TE(iMoCo UTE) for high resolution free breathing pulmonary MRI](https://mlsanity.com/paper/2001.11993/) (2020)
- [Dynamic imaging using Motion-Compensated SmooThness Regularization on Manifolds (MoCo-SToRM)](https://mlsanity.com/paper/2112.03380/) (2021)

## Built on by (most cited first, 1 of 1)

- [Spatiotemporal Gaussian representation-based dynamic reconstruction and motion estimation framework for time-resolved volumetric MR imaging (DREME-GSMR)](https://mlsanity.com/paper/2604.06482/) (2026)

## Abstract (arXiv)

This study presents an unsupervised, motion-resolved reconstruction framework for high-resolution, free-breathing pulmonary magnetic resonance imaging (MRI), utilizing a three-dimensional Gaussian representation (3DGS). The proposed method leverages 3DGS to address the challenges of motion-resolved 3D isotropic pulmonary MRI reconstruction by enabling data smoothing between voxels for continuous spatial representation. Pulmonary MRI data acquisition is performed using a golden-angle radial sampling trajectory, with respiratory motion signals extracted from the center of k-space in each radial spoke. Based on the estimated motion signal, the k-space data is sorted into multiple respiratory phases. A 3DGS framework is then applied to reconstruct a reference image volume from the first motion state. Subsequently, a patient-specific convolutional neural network is trained to estimate the deformation vector fields (DVFs), which are used to generate the remaining motion states through spatial transformation of the reference volume. The proposed reconstruction pipeline is evaluated on six datasets from six subjects and bench-marked against three state-of-the-art reconstruction methods. The experimental findings demonstrate that the proposed reconstruction framework effectively reconstructs high-resolution, motion-resolved pulmonary MR images. Compared with existing approaches, it achieves superior image quality, reflected by higher signal-to-noise ratio and contrast-to-noise ratio. The proposed unsupervised 3DGS-based reconstruction method enables accurate motion-resolved pulmonary MRI with isotropic spatial resolution. Its superior performance in image quality metrics over state-of-the-art methods highlights its potential as a robust solution for clinical pulmonary MR imaging.
