# Natural Language Generation in Healthcare: A Review of Methods and Applications

arXiv: https://arxiv.org/abs/2505.04073 · HTML: https://mlsanity.com/paper/2505.04073/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Builds on 56 of its 133 references that are in the map.
- First posted on arXiv 7 May 2025.

## Builds on (most cited first, 30 of 56)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [Exploring the Limits of Transfer Learning with a Unified Text-to-Text Transformer](https://mlsanity.com/paper/1910.10683/) (2019)
- [LLaMA: Open and Efficient Foundation Language Models](https://mlsanity.com/paper/2302.13971/) (2023)
- [BERTScore: Evaluating Text Generation with BERT](https://mlsanity.com/paper/1904.09675/) (2019)
- [Sequence to Sequence Learning with Neural Networks](https://mlsanity.com/paper/1409.3215/) (2014)
- [CIDEr: Consensus-based Image Description Evaluation](https://mlsanity.com/paper/1411.5726/) (2014)
- [CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparison](https://mlsanity.com/paper/1901.07031/) (2019)
- [LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day](https://mlsanity.com/paper/2306.00890/) (2023)
- [BLEURT: Learning Robust Metrics for Text Generation](https://mlsanity.com/paper/2004.04696/) (2020)
- [BiomedCLIP: a multimodal biomedical foundation model pretrained from fifteen million scientific image-text pairs](https://mlsanity.com/paper/2303.00915/) (2023)
- [A Survey of Transformers](https://mlsanity.com/paper/2106.04554/) (2021)
- [Med-Flamingo: a Multimodal Medical Few-shot Learner](https://mlsanity.com/paper/2307.15189/) (2023)
- [Generating Radiology Reports via Memory-driven Transformer](https://mlsanity.com/paper/2010.16056/) (2020)
- [CheXbert: Combining Automatic Labelers and Expert Annotations for Accurate Radiology Report Labeling Using BERT](https://mlsanity.com/paper/2004.09167/) (2020)
- [RadGraph: Extracting Clinical Entities and Relations from Radiology Reports](https://mlsanity.com/paper/2106.14463/) (2021)
- [Adapted Large Language Models Can Outperform Medical Experts in Clinical Text Summarization](https://mlsanity.com/paper/2309.07430/) (2023)
- [Survey of the State of the Art in Natural Language Generation: Core tasks, applications and evaluation](https://mlsanity.com/paper/1703.09902/) (2017)
- [BiomedGPT: A Generalist Vision-Language Foundation Model for Diverse Biomedical Tasks](https://mlsanity.com/paper/2305.17100/) (2023)
- [Cross-modal Memory Networks for Radiology Report Generation](https://mlsanity.com/paper/2204.13258/) (2022)
- [A Study of Generative Large Language Model for Medical Research and Healthcare](https://mlsanity.com/paper/2305.13523/) (2023)
- [Improving Factual Completeness and Consistency of Image-to-Text Radiology Report Generation](https://mlsanity.com/paper/2010.10042/) (2020)
- [Towards Accurate Differential Diagnosis with Large Language Models](https://mlsanity.com/paper/2312.00164/) (2023)
- [Radiology Report Generation with a Learned Knowledge Base and Multi-modal Alignment](https://mlsanity.com/paper/2112.15011/) (2021)
- [A Comprehensive Survey on Applications of Transformers for Deep Learning Tasks](https://mlsanity.com/paper/2306.07303/) (2023)
- [Generating SOAP Notes from Doctor-Patient Conversations Using Modular Summarization Techniques](https://mlsanity.com/paper/2005.01795/) (2020)
- [Dr. Summarize: Global Summarization of Medical Dialogue by Exploiting Local Structures](https://mlsanity.com/paper/2009.08666/) (2020)
- [Leveraging Pretrained Models for Automatic Summarization of Doctor-Patient Conversations](https://mlsanity.com/paper/2109.12174/) (2021)
- [Weakly Supervised Contrastive Learning for Chest X-Ray Report Generation](https://mlsanity.com/paper/2109.12242/) (2021)
- [Semi-Supervised Variational Reasoning for Medical Dialogue Generation](https://mlsanity.com/paper/2105.06071/) (2021)

## Built on by (most cited first, 3 of 3)

- [Countering Catastrophic Forgetting of Large Language Models for Better Instruction Following via Weight-Space Model Merging](https://mlsanity.com/paper/2604.01538/) (2026)
- [Detecting HIV-Related Stigma in Clinical Narratives Using Large Language Models](https://mlsanity.com/paper/2604.07717/) (2026)
- [Automated Clinical Report Generation for Remote Cognitive Remediation: Comparing Knowledge-Engineered Templates and LLMs in Low-Resource Settings](https://mlsanity.com/paper/2605.06594/) (2026)

## Abstract (arXiv)

Natural language generation (NLG) is the key technology to achieve generative artificial intelligence (AI). With the breakthroughs in large language models (LLMs), NLG has been widely used in various medical applications, demonstrating the potential to enhance clinical workflows, support clinical decision-making, and improve clinical documentation. Heterogeneous and diverse medical data modalities, such as medical text, images, and knowledge bases, are utilized in NLG. Researchers have proposed many generative models and applied them in a number of healthcare applications. There is a need for a comprehensive review of NLG methods and applications in the medical domain. In this study, we systematically reviewed 113 scientific publications from a total of 3,988 NLG-related articles identified using a literature search, focusing on data modality, model architecture, clinical applications, and evaluation methods. Following PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) guidelines, we categorize key methods, identify clinical applications, and assess their capabilities, limitations, and emerging challenges. This timely review covers the key NLG technologies and medical applications and provides valuable insights for future studies to leverage NLG to transform medical discovery and healthcare.
