# From Pixels to Polygons: A Survey of Deep Learning Approaches for Medical Image-to-Mesh Reconstruction

arXiv: https://arxiv.org/abs/2505.03599 · HTML: https://mlsanity.com/paper/2505.03599/

## Key facts

- Cited by 4 papers in the map (data through 14 Oct 2026).
- Builds on 81 of its 194 references that are in the map.
- First posted on arXiv 6 May 2025.

## Builds on (most cited first, 30 of 81)

- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [Denoising Diffusion Implicit Models](https://mlsanity.com/paper/2010.02502/) (2020)
- [EfficientNet: Rethinking Model Scaling for Convolutional Neural Networks](https://mlsanity.com/paper/1905.11946/) (2019)
- [3D Gaussian Splatting for Real-Time Radiance Field Rendering](https://mlsanity.com/paper/2308.04079/) (2023)
- [PointNet: Deep Learning on Point Sets for 3D Classification and Segmentation](https://mlsanity.com/paper/1612.00593/) (2016)
- [Neural Discrete Representation Learning](https://mlsanity.com/paper/1711.00937/) (2017)
- [MobileNets: Efficient Convolutional Neural Networks for Mobile Vision Applications](https://mlsanity.com/paper/1704.04861/) (2017)
- [Instant Neural Graphics Primitives with a Multiresolution Hash Encoding](https://mlsanity.com/paper/2201.05989/) (2022)
- [Mip-NeRF: A Multiscale Representation for Anti-Aliasing Neural Radiance Fields](https://mlsanity.com/paper/2103.13415/) (2021)
- [NeuS: Learning Neural Implicit Surfaces by Volume Rendering for Multi-view Reconstruction](https://mlsanity.com/paper/2106.10689/) (2021)
- [2D Gaussian Splatting for Geometrically Accurate Radiance Fields](https://mlsanity.com/paper/2403.17888/) (2024)
- [Volume Rendering of Neural Implicit Surfaces](https://mlsanity.com/paper/2106.12052/) (2021)
- [A Point Set Generation Network for 3D Object Reconstruction from a Single Image](https://mlsanity.com/paper/1612.00603/) (2016)
- [DreamGaussian: Generative Gaussian Splatting for Efficient 3D Content Creation](https://mlsanity.com/paper/2309.16653/) (2023)
- [VoxelMorph: A Learning Framework for Deformable Medical Image Registration](https://mlsanity.com/paper/1809.05231/) (2018)
- [SuGaR: Surface-Aligned Gaussian Splatting for Efficient 3D Mesh Reconstruction and High-Quality Mesh Rendering](https://mlsanity.com/paper/2311.12775/) (2023)
- [Neuralangelo: High-Fidelity Neural Surface Reconstruction](https://mlsanity.com/paper/2306.03092/) (2023)
- [A large annotated medical image dataset for the development and evaluation of segmentation algorithms](https://mlsanity.com/paper/1902.09063/) (2019)
- [NeuS2: Fast Learning of Neural Implicit Surfaces for Multi-view Reconstruction](https://mlsanity.com/paper/2212.05231/) (2022)
- [PGSR: Planar-based Gaussian Splatting for Efficient and High-Fidelity Surface Reconstruction](https://mlsanity.com/paper/2406.06521/) (2024)
- [Diffusion Models for Medical Image Analysis: A Comprehensive Survey](https://mlsanity.com/paper/2211.07804/) (2022)
- [Gaussian Opacity Fields: Efficient Adaptive Surface Reconstruction in Unbounded Scenes](https://mlsanity.com/paper/2404.10772/) (2024)
- [BakedSDF: Meshing Neural SDFs for Real-Time View Synthesis](https://mlsanity.com/paper/2302.14859/) (2023)
- [PU-Net: Point Cloud Upsampling Network](https://mlsanity.com/paper/1801.06761/) (2018)
- [NeRO: Neural Geometry and BRDF Reconstruction of Reflective Objects from Multiview Images](https://mlsanity.com/paper/2305.17398/) (2023)
- [High-quality Surface Reconstruction using Gaussian Surfels](https://mlsanity.com/paper/2404.17774/) (2024)
- [Relightable 3D Gaussians: Realistic Point Cloud Relighting with BRDF Decomposition and Ray Tracing](https://mlsanity.com/paper/2311.16043/) (2023)
- [MeshSDF: Differentiable Iso-Surface Extraction](https://mlsanity.com/paper/2006.03997/) (2020)

## Built on by (most cited first, 4 of 4)

- [From 2D to 3D, Deep Learning-based Shape Reconstruction in Magnetic Resonance Imaging: A Review](https://mlsanity.com/paper/2510.01296/) (2025)
- [High-Fidelity 3D Geometric Reconstruction of Pelvic Organs from MRI: A Hybrid Deep Learning and Iterative Optimization Approach](https://mlsanity.com/paper/2606.17836/) (2026)
- [HeartVolMesh: Cardiac Volumetric Mesh Reconstruction via Covariance-Guided Graph Deformation](https://mlsanity.com/paper/2607.04243/) (2026)
- [A Strong Linear Baseline for Whole-Heart Cardiac Shape Completion on CT, with an Open Eleven-Structure Statistical Shape Model](https://mlsanity.com/paper/2608.19932/) (2026)

## Abstract (arXiv)

Deep learning-based medical image-to-mesh reconstruction has rapidly evolved, enabling the transformation of medical imaging data into three-dimensional mesh models that are critical in computational medicine and in silico trials for advancing our understanding of disease mechanisms, and diagnostic and therapeutic techniques in modern medicine. This survey systematically categorizes existing approaches into four main categories: template models, statistical models, generative models, and implicit models. Each category is analysed in detail, examining their methodological foundations, strengths, limitations, and applicability to different anatomical structures and imaging modalities. We provide an extensive evaluation of these methods across various anatomical applications, from cardiac imaging to neurological studies, supported by quantitative comparisons using standard metrics. Additionally, we compile and analyze major public datasets available for medical mesh reconstruction tasks and discuss commonly used evaluation metrics and loss functions. The survey identifies current challenges in the field, including requirements for topological correctness, geometric accuracy, and multi-modality integration. Finally, we present promising future research directions in this domain. This systematic review aims to serve as a comprehensive reference for researchers and practitioners in medical image analysis and computational medicine.