# SimICD: A Closed-Loop Simulation Framework For ICD Therapy

arXiv: https://arxiv.org/abs/2505.01371 · HTML: https://mlsanity.com/paper/2505.01371/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 2 May 2025.

## Built on by (most cited first, 1 of 1)

- [Physics-Informed Neural Operators for Cardiac Electrophysiology](https://mlsanity.com/paper/2511.08418/) (2025)

## Abstract (arXiv)

Virtual studies of ICD behaviour are crucial for testing device functionality in a controlled environment prior to clinical application. Although previous works have shown the viability of using in silico testing for diagnosis, there is a notable gap in available models that can simulate therapy progression decisions during arrhythmic episodes. This work introduces SimICD, a simulation tool which combines virtual ICD logic algorithms with cardiac electrophysiology simulations in a feedback loop, allowing the progression of ICD therapy protocols to be simulated for a range of tachy-arrhythmia episodes. Using a cohort of virtual patients, we demonstrate the ability of SimICD to simulate realistic cardiac signals and ICD responses that align with the logic of real-world devices, facilitating the reprogramming of ICD parameters to adapt to specific episodes.