# Keep the General, Inject the Specific: Structured Dialogue Fine-Tuning for Knowledge Injection without Catastrophic Forgetting

arXiv: https://arxiv.org/abs/2505.00029 · HTML: https://mlsanity.com/paper/2505.00029/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in MLLM training and visual instruction tuning, one of 16 directions in Multimodal LLMs / vision-language models.
- Builds on 31 of its 45 references that are in the map.
- First posted on arXiv 27 Apr 2025.

## Placed in

- Multimodal LLMs / vision-language models / [MLLM training and visual instruction tuning](https://mlsanity.com/mllm/mllm-training-and-visual-instruction-tuning/)

## Builds on (most cited first, 30 of 31)

- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [Direct Preference Optimization: Your Language Model is Secretly a Reward Model](https://mlsanity.com/paper/2305.18290/) (2023)
- [Overcoming catastrophic forgetting in neural networks](https://mlsanity.com/paper/1612.00796/) (2016)
- [Parameter-Efficient Transfer Learning for NLP](https://mlsanity.com/paper/1902.00751/) (2019)
- [DreamBooth: Fine Tuning Text-to-Image Diffusion Models for Subject-Driven Generation](https://mlsanity.com/paper/2208.12242/) (2022)
- [Evaluating Object Hallucination in Large Vision-Language Models](https://mlsanity.com/paper/2305.10355/) (2023)
- [Towards VQA Models That Can Read](https://mlsanity.com/paper/1904.08920/) (2019)
- [LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day](https://mlsanity.com/paper/2306.00890/) (2023)
- [How Far Are We to GPT-4V? Closing the Gap to Commercial Multimodal Models with Open-Source Suites](https://mlsanity.com/paper/2404.16821/) (2024)
- [BloombergGPT: A Large Language Model for Finance](https://mlsanity.com/paper/2303.17564/) (2023)
- [Towards Expert-Level Medical Question Answering with Large Language Models](https://mlsanity.com/paper/2305.09617/) (2023)
- [InstantBooth: Personalized Text-to-Image Generation without Test-Time Finetuning](https://mlsanity.com/paper/2304.03411/) (2023)
- [K-Adapter: Infusing Knowledge into Pre-Trained Models with Adapters](https://mlsanity.com/paper/2002.01808/) (2020)
- [Fine-tuning Language Models for Factuality](https://mlsanity.com/paper/2311.08401/) (2023)
- [Memorization Without Overfitting: Analyzing the Training Dynamics of Large Language Models](https://mlsanity.com/paper/2205.10770/) (2022)
- [Fine-Tuning or Retrieval? Comparing Knowledge Injection in LLMs](https://mlsanity.com/paper/2312.05934/) (2023)
- [Domain Specialization as the Key to Make Large Language Models Disruptive: A Comprehensive Survey](https://mlsanity.com/paper/2305.18703/) (2023)
- [GeneGPT: Augmenting Large Language Models with Domain Tools for Improved Access to Biomedical Information](https://mlsanity.com/paper/2304.09667/) (2023)
- [PMC-LLaMA: Towards Building Open-source Language Models for Medicine](https://mlsanity.com/paper/2304.14454/) (2023)
- [Learning without Forgetting for Vision-Language Models](https://mlsanity.com/paper/2305.19270/) (2023)
- [Contrastive Region Guidance: Improving Grounding in Vision-Language Models without Training](https://mlsanity.com/paper/2403.02325/) (2024)
- [Yo'LLaVA: Your Personalized Language and Vision Assistant](https://mlsanity.com/paper/2406.09400/) (2024)
- [Instruct-FinGPT: Financial Sentiment Analysis by Instruction Tuning of General-Purpose Large Language Models](https://mlsanity.com/paper/2306.12659/) (2023)
- [MyVLM: Personalizing VLMs for User-Specific Queries](https://mlsanity.com/paper/2403.14599/) (2024)
- [From Skepticism to Acceptance: Simulating the Attitude Dynamics Toward Fake News](https://mlsanity.com/paper/2403.09498/) (2024)
- [Injecting Domain-Specific Knowledge into Large Language Models: A Comprehensive Survey](https://mlsanity.com/paper/2502.10708/) (2025)
- [Imagine yourself: Tuning-Free Personalized Image Generation](https://mlsanity.com/paper/2409.13346/) (2024)
- [RAP: Retrieval-Augmented Personalization for Multimodal Large Language Models](https://mlsanity.com/paper/2410.13360/) (2024)
- [KILM: Knowledge Injection into Encoder-Decoder Language Models](https://mlsanity.com/paper/2302.09170/) (2023)

## Abstract (arXiv)

Large Vision Language Models have demonstrated impressive versatile capabilities through extensive multimodal pre-training, but face significant limitations when incorporating specialized knowledge domains beyond their training distribution. These models struggle with a fundamental dilemma: direct adaptation approaches that inject domain-specific knowledge often trigger catastrophic forgetting of foundational visual-linguistic abilities. We introduce Structured Dialogue Fine-Tuning (SDFT), an effective approach that effectively injects domain-specific knowledge while minimizing catastrophic forgetting. Drawing inspiration from supervised fine-tuning in LLMs and subject-driven personalization in text-to-image diffusion models, our method employs a three-phase dialogue structure: Foundation Preservation reinforces pre-trained visual-linguistic alignment through caption tasks; Contrastive Disambiguation introduces carefully designed counterfactual examples to maintain semantic boundaries; and Knowledge Specialization embeds specialized information through chain-of-thought reasoning. Experimental results across multiple domains confirm SDFT's effectiveness in balancing specialized knowledge acquisition with general capability retention. Our key contributions include a data-centric dialogue template that balances foundational alignment with targeted knowledge integration, a weighted multi-turn supervision framework, and comprehensive evaluation across diverse knowledge types.
