# xEEGNet: Towards Explainable AI in EEG Dementia Classification

arXiv: https://arxiv.org/abs/2504.21457 · HTML: https://mlsanity.com/paper/2504.21457/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 14 of its 67 references that are in the map.
- First posted on arXiv 30 Apr 2025.

## Builds on (most cited first, 14 of 14)

- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [Distilling the Knowledge in a Neural Network](https://mlsanity.com/paper/1503.02531/) (2015)
- [Batch Normalization: Accelerating Deep Network Training by Reducing Internal Covariate Shift](https://mlsanity.com/paper/1502.03167/) (2015)
- [Grad-CAM: Visual Explanations from Deep Networks via Gradient-based Localization](https://mlsanity.com/paper/1610.02391/) (2016)
- [Xception: Deep Learning with Depthwise Separable Convolutions](https://mlsanity.com/paper/1610.02357/) (2016)
- [Explanation in Artificial Intelligence: Insights from the Social Sciences](https://mlsanity.com/paper/1706.07269/) (2017)
- [EEGNet: A Compact Convolutional Network for EEG-based Brain-Computer Interfaces](https://mlsanity.com/paper/1611.08024/) (2016)
- [Network In Network](https://mlsanity.com/paper/1312.4400/) (2013)
- [Formalizing Trust in Artificial Intelligence: Prerequisites, Causes and Goals of Human Trust in AI](https://mlsanity.com/paper/2010.07487/) (2020)
- [Deep learning-based electroencephalography analysis: a systematic review](https://mlsanity.com/paper/1901.05498/) (2019)
- [Transparency of Deep Neural Networks for Medical Image Analysis: A Review of Interpretability Methods](https://mlsanity.com/paper/2111.02398/) (2021)
- [FBCNet: A Multi-view Convolutional Neural Network for Brain-Computer Interface](https://mlsanity.com/paper/2104.01233/) (2021)
- [NetScore: Towards Universal Metrics for Large-scale Performance Analysis of Deep Neural Networks for Practical On-Device Edge Usage](https://mlsanity.com/paper/1806.05512/) (2018)
- [SelfEEG: A Python library for Self-Supervised Learning in Electroencephalography](https://mlsanity.com/paper/2401.05405/) (2023)

## Built on by (most cited first, 1 of 1)

- [TransformEEG: Towards Improving Model Generalizability in Deep Learning-based EEG Parkinson's Disease Detection](https://mlsanity.com/paper/2507.07622/) (2025)

## Abstract (arXiv)

This work presents xEEGNet, a novel, compact, and explainable neural network for EEG data analysis. It is fully interpretable and reduces overfitting through major parameter reduction. As an applicative use case, we focused on classifying common dementia conditions, Alzheimer's and frontotemporal dementia, versus controls. xEEGNet is broadly applicable to other neurological conditions involving spectral alterations. We initially used ShallowNet, a simple and popular model from the EEGNet-family. Its structure was analyzed and gradually modified to move from a "black box" to a more transparent model, without compromising performance. The learned kernels and weights were examined from a clinical standpoint to assess medical relevance. Model variants, including ShallowNet and the final xEEGNet, were evaluated using robust Nested-Leave-N-Subjects-Out cross-validation for unbiased performance estimates. Variability across data splits was explained using embedded EEG representations, grouped by class and set, with pairwise separability to quantify group distinction. Overfitting was assessed through training-validation loss correlation and training speed. xEEGNet uses only 168 parameters, 200 times fewer than ShallowNet, yet retains interpretability, resists overfitting, achieves comparable median performance (-1.5%), and reduces variability across splits. This variability is explained by embedded EEG representations: higher accuracy correlates with greater separation between test set controls and Alzheimer's cases, without significant influence from training data. xEEGNet's ability to filter specific EEG bands, learn band-specific topographies, and use relevant spectral features demonstrates its interpretability. While large deep learning models are often prioritized for performance, this study shows smaller architectures like xEEGNet can be equally effective in EEG pathology classification.