# Model Connectomes: A Generational Approach to Data-Efficient Language Models

arXiv: https://arxiv.org/abs/2504.21047 · HTML: https://mlsanity.com/paper/2504.21047/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 35 of its 64 references that are in the map.
- First posted on arXiv 29 Apr 2025.

## Builds on (most cited first, 30 of 35)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Distilling the Knowledge in a Neural Network](https://mlsanity.com/paper/1503.02531/) (2015)
- [Measuring Massive Multitask Language Understanding](https://mlsanity.com/paper/2009.03300/) (2020)
- [Scaling Laws for Neural Language Models](https://mlsanity.com/paper/2001.08361/) (2020)
- [RoFormer: Enhanced Transformer with Rotary Position Embedding](https://mlsanity.com/paper/2104.09864/) (2021)
- [HellaSwag: Can a Machine Really Finish Your Sentence?](https://mlsanity.com/paper/1905.07830/) (2019)
- [Outrageously Large Neural Networks: The Sparsely-Gated Mixture-of-Experts Layer](https://mlsanity.com/paper/1701.06538/) (2017)
- [The Lottery Ticket Hypothesis: Finding Sparse, Trainable Neural Networks](https://mlsanity.com/paper/1803.03635/) (2018)
- [Learning both Weights and Connections for Efficient Neural Networks](https://mlsanity.com/paper/1506.02626/) (2015)
- [GPTQ: Accurate Post-Training Quantization for Generative Pre-trained Transformers](https://mlsanity.com/paper/2210.17323/) (2022)
- [Root Mean Square Layer Normalization](https://mlsanity.com/paper/1910.07467/) (2019)
- [Big Self-Supervised Models are Strong Semi-Supervised Learners](https://mlsanity.com/paper/2006.10029/) (2020)
- [Interpretability in the Wild: a Circuit for Indirect Object Identification in GPT-2 small](https://mlsanity.com/paper/2211.00593/) (2022)
- [The FineWeb Datasets: Decanting the Web for the Finest Text Data at Scale](https://mlsanity.com/paper/2406.17557/) (2024)
- [Pruning neural networks without any data by iteratively conserving synaptic flow](https://mlsanity.com/paper/2006.05467/) (2020)
- [Sparse Feature Circuits: Discovering and Editing Interpretable Causal Graphs in Language Models](https://mlsanity.com/paper/2403.19647/) (2024)
- [Movement Pruning: Adaptive Sparsity by Fine-Tuning](https://mlsanity.com/paper/2005.07683/) (2020)
- [PathNet: Evolution Channels Gradient Descent in Super Neural Networks](https://mlsanity.com/paper/1701.08734/) (2017)
- [Deconstructing Lottery Tickets: Zeros, Signs, and the Supermask](https://mlsanity.com/paper/1905.01067/) (2019)
- [Interpreting and improving natural-language processing (in machines) with natural language-processing (in the brain)](https://mlsanity.com/paper/1905.11833/) (2019)
- [On the Predictive Power of Neural Language Models for Human Real-Time Comprehension Behavior](https://mlsanity.com/paper/2006.01912/) (2020)
- [Why Does Surprisal From Larger Transformer-Based Language Models Provide a Poorer Fit to Human Reading Times?](https://mlsanity.com/paper/2212.12131/) (2022)
- [What Artificial Neural Networks Can Tell Us About Human Language Acquisition](https://mlsanity.com/paper/2208.07998/) (2022)
- [Toward Next-Generation Artificial Intelligence: Catalyzing the NeuroAI Revolution](https://mlsanity.com/paper/2210.08340/) (2022)
- [Call for Papers -- The BabyLM Challenge: Sample-efficient pretraining on a developmentally plausible corpus](https://mlsanity.com/paper/2301.11796/) (2023)
- [Transformer-Based Language Model Surprisal Predicts Human Reading Times Best with About Two Billion Training Tokens](https://mlsanity.com/paper/2304.11389/) (2023)
- [The Natural Stories Corpus](https://mlsanity.com/paper/1708.05763/) (2017)
- [Instruction-tuning Aligns LLMs to the Human Brain](https://mlsanity.com/paper/2312.00575/) (2023)
- [Frequency Explains the Inverse Correlation of Large Language Models' Size, Training Data Amount, and Surprisal's Fit to Reading Times](https://mlsanity.com/paper/2402.02255/) (2024)
- [Unmasking the Lottery Ticket Hypothesis: What's Encoded in a Winning Ticket's Mask?](https://mlsanity.com/paper/2210.03044/) (2022)

## Abstract (arXiv)

Biological neural networks are shaped both by evolution across generations and by individual learning within an organism's lifetime, whereas standard artificial neural networks undergo a single, large training procedure without inherited constraints. In this preliminary work, we propose a framework that incorporates this crucial generational dimension - an "outer loop" of evolution that shapes the "inner loop" of learning - so that artificial networks better mirror the effects of evolution and individual learning in biological organisms. Focusing on language, we train a model that inherits a "model connectome" from the outer evolution loop before exposing it to a developmental-scale corpus of 100M tokens. Compared with two closely matched control models, we show that the connectome model performs better or on par on natural language processing tasks as well as alignment to human behavior and brain data. These findings suggest that a model connectome serves as an efficient prior for learning in low-data regimes - narrowing the gap between single-generation artificial models and biologically evolved neural networks.