# MedNNS: Supernet-based Medical Task-Adaptive Neural Network Search

arXiv: https://arxiv.org/abs/2504.15865 · HTML: https://mlsanity.com/paper/2504.15865/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 17 of its 28 references that are in the map.
- First posted on arXiv 22 Apr 2025.

## Builds on (most cited first, 17 of 17)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [EfficientNet: Rethinking Model Scaling for Convolutional Neural Networks](https://mlsanity.com/paper/1905.11946/) (2019)
- [Learning Transferable Architectures for Scalable Image Recognition](https://mlsanity.com/paper/1707.07012/) (2017)
- [MnasNet: Platform-Aware Neural Architecture Search for Mobile](https://mlsanity.com/paper/1807.11626/) (2018)
- [Once-for-All: Train One Network and Specialize it for Efficient Deployment](https://mlsanity.com/paper/1908.09791/) (2019)
- [MedMNIST v2 -- A large-scale lightweight benchmark for 2D and 3D biomedical image classification](https://mlsanity.com/paper/2110.14795/) (2021)
- [ProxylessNAS: Direct Neural Architecture Search on Target Task and Hardware](https://mlsanity.com/paper/1812.00332/) (2018)
- [Progressive Neural Architecture Search](https://mlsanity.com/paper/1712.00559/) (2017)
- [Transfusion: Understanding Transfer Learning for Medical Imaging](https://mlsanity.com/paper/1902.07208/) (2019)
- [Neural Architecture Search: Insights from 1000 Papers](https://mlsanity.com/paper/2301.08727/) (2023)
- [FairNAS: Rethinking Evaluation Fairness of Weight Sharing Neural Architecture Search](https://mlsanity.com/paper/1907.01845/) (2019)
- [What Makes Transfer Learning Work For Medical Images: Feature Reuse & Other Factors](https://mlsanity.com/paper/2203.01825/) (2022)
- [HardCoRe-NAS: Hard Constrained diffeRentiable Neural Architecture Search](https://mlsanity.com/paper/2102.11646/) (2021)
- [Task-Adaptive Neural Network Search with Meta-Contrastive Learning](https://mlsanity.com/paper/2103.01495/) (2021)
- [An Effective Weight Initialization Method for Deep Learning: Application to Satellite Image Classification](https://mlsanity.com/paper/2406.00348/) (2024)

## Abstract (arXiv)

Deep learning (DL) has achieved remarkable progress in the field of medical imaging. However, adapting DL models to medical tasks remains a significant challenge, primarily due to two key factors: (1) architecture selection, as different tasks necessitate specialized model designs, and (2) weight initialization, which directly impacts the convergence speed and final performance of the models. Although transfer learning from ImageNet is a widely adopted strategy, its effectiveness is constrained by the substantial differences between natural and medical images. To address these challenges, we introduce Medical Neural Network Search (MedNNS), the first Neural Network Search framework for medical imaging applications. MedNNS jointly optimizes architecture selection and weight initialization by constructing a meta-space that encodes datasets and models based on how well they perform together. We build this space using a Supernetwork-based approach, expanding the model zoo size by 51x times over previous state-of-the-art (SOTA) methods. Moreover, we introduce rank loss and Fr'echet Inception Distance (FID) loss into the construction of the space to capture inter-model and inter-dataset relationships, thereby achieving more accurate alignment in the meta-space. Experimental results across multiple datasets demonstrate that MedNNS significantly outperforms both ImageNet pre-trained DL models and SOTA Neural Architecture Search (NAS) methods, achieving an average accuracy improvement of 1.7% across datasets while converging substantially faster. The code and the processed meta-space is available at https://github.com/BioMedIA-MBZUAI/MedNNS.