# Med-CoDE: Medical Critique based Disagreement Evaluation Framework

arXiv: https://arxiv.org/abs/2504.15330 · HTML: https://mlsanity.com/paper/2504.15330/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 16 of its 28 references that are in the map.
- First posted on arXiv 21 Apr 2025.

## Builds on (most cited first, 16 of 16)

- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [Measuring Massive Multitask Language Understanding](https://mlsanity.com/paper/2009.03300/) (2020)
- [BERTScore: Evaluating Text Generation with BERT](https://mlsanity.com/paper/1904.09675/) (2019)
- [G-Eval: NLG Evaluation using GPT-4 with Better Human Alignment](https://mlsanity.com/paper/2303.16634/) (2023)
- [PubMedQA: A Dataset for Biomedical Research Question Answering](https://mlsanity.com/paper/1909.06146/) (2019)
- [Can Large Language Models Be an Alternative to Human Evaluations?](https://mlsanity.com/paper/2305.01937/) (2023)
- [Prometheus: Inducing Fine-grained Evaluation Capability in Language Models](https://mlsanity.com/paper/2310.08491/) (2023)
- [Large Language Models Are State-of-the-Art Evaluators of Translation Quality](https://mlsanity.com/paper/2302.14520/) (2023)
- [BioMistral: A Collection of Open-Source Pretrained Large Language Models for Medical Domains](https://mlsanity.com/paper/2402.10373/) (2024)
- [Shepherd: A Critic for Language Model Generation](https://mlsanity.com/paper/2308.04592/) (2023)
- [OpenMEVA: A Benchmark for Evaluating Open-ended Story Generation Metrics](https://mlsanity.com/paper/2105.08920/) (2021)
- [Automatic Interactive Evaluation for Large Language Models with State Aware Patient Simulator](https://mlsanity.com/paper/2403.08495/) (2024)
- [Medical Exam Question Answering with Large-scale Reading Comprehension](https://mlsanity.com/paper/1802.10279/) (2018)
- [X-Eval: Generalizable Multi-aspect Text Evaluation via Augmented Instruction Tuning with Auxiliary Evaluation Aspects](https://mlsanity.com/paper/2311.08788/) (2023)
- [Towards Automatic Evaluation for LLMs' Clinical Capabilities: Metric, Data, and Algorithm](https://mlsanity.com/paper/2403.16446/) (2024)
- [Perception Score, A Learned Metric for Open-ended Text Generation Evaluation](https://mlsanity.com/paper/2008.03082/) (2020)

## Built on by (most cited first, 2 of 2)

- [VIS-Shepherd: Constructing Critic for LLM-based Data Visualization Generation](https://mlsanity.com/paper/2506.13326/) (2025)
- [Blinded Radiologist and LLM-Based Evaluation of LLM-Generated Japanese Translations of Chest CT Reports: Comparative Study](https://mlsanity.com/paper/2604.02207/) (2026)

## Abstract (arXiv)

The emergence of large language models (LLMs) has significantly influenced numerous fields, including healthcare, by enhancing the capabilities of automated systems to process and generate human-like text. However, despite their advancements, the reliability and accuracy of LLMs in medical contexts remain critical concerns. Current evaluation methods often lack robustness and fail to provide a comprehensive assessment of LLM performance, leading to potential risks in clinical settings. In this work, we propose Med-CoDE, a specifically designed evaluation framework for medical LLMs to address these challenges. The framework leverages a critique-based approach to quantitatively measure the degree of disagreement between model-generated responses and established medical ground truths. This framework captures both accuracy and reliability in medical settings. The proposed evaluation framework aims to fill the existing gap in LLM assessment by offering a systematic method to evaluate the quality and trustworthiness of medical LLMs. Through extensive experiments and case studies, we illustrate the practicality of our framework in providing a comprehensive and reliable evaluation of medical LLMs.