# 3MDBench: Medical Multimodal Multi-agent Dialogue Benchmark

arXiv: https://arxiv.org/abs/2504.13861 · HTML: https://mlsanity.com/paper/2504.13861/

## Key facts

- Cited by 16 papers in the map (data through 14 Oct 2026).
- Placed in Medical vision-language models, one of 16 directions in Multimodal LLMs / vision-language models.
- Builds on 38 of its 110 references that are in the map.
- First posted on arXiv 26 Mar 2025.

## Placed in

- Multimodal LLMs / vision-language models / [Medical vision-language models](https://mlsanity.com/mllm/medical-vision-language-models/)
- LLM agents and tool use / [Medical and scientific domain agents](https://mlsanity.com/agents/medical-and-scientific-domain-agents/)

## Builds on (most cited first, 30 of 38)

- [The Llama 3 Herd of Models](https://mlsanity.com/paper/2407.21783/) (2024)
- [Judging LLM-as-a-Judge with MT-Bench and Chatbot Arena](https://mlsanity.com/paper/2306.05685/) (2023)
- [ImageNet Large Scale Visual Recognition Challenge](https://mlsanity.com/paper/1409.0575/) (2014)
- [Qwen2-VL: Enhancing Vision-Language Model's Perception of the World at Any Resolution](https://mlsanity.com/paper/2409.12191/) (2024)
- [LLaVA-OneVision: Easy Visual Task Transfer](https://mlsanity.com/paper/2408.03326/) (2024)
- [Qwen-VL: A Versatile Vision-Language Model for Understanding, Localization, Text Reading, and Beyond](https://mlsanity.com/paper/2308.12966/) (2023)
- [Qwen2 Technical Report](https://mlsanity.com/paper/2407.10671/) (2024)
- [What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Exams](https://mlsanity.com/paper/2009.13081/) (2020)
- [PubMedQA: A Dataset for Biomedical Research Question Answering](https://mlsanity.com/paper/1909.06146/) (2019)
- [EfficientNetV2: Smaller Models and Faster Training](https://mlsanity.com/paper/2104.00298/) (2021)
- [DeepSeek-VL: Towards Real-World Vision-Language Understanding](https://mlsanity.com/paper/2403.05525/) (2024)
- [LLM Evaluators Recognize and Favor Their Own Generations](https://mlsanity.com/paper/2404.13076/) (2024)
- [The Falcon Series of Open Language Models](https://mlsanity.com/paper/2311.16867/) (2023)
- [PathVQA: 30000+ Questions for Medical Visual Question Answering](https://mlsanity.com/paper/2003.10286/) (2020)
- [NV-Embed: Improved Techniques for Training LLMs as Generalist Embedding Models](https://mlsanity.com/paper/2405.17428/) (2024)
- [SLAKE: A Semantically-Labeled Knowledge-Enhanced Dataset for Medical Visual Question Answering](https://mlsanity.com/paper/2102.09542/) (2021)
- [Med-Flamingo: a Multimodal Medical Few-shot Learner](https://mlsanity.com/paper/2307.15189/) (2023)
- [EndoNet: A Deep Architecture for Recognition Tasks on Laparoscopic Videos](https://mlsanity.com/paper/1602.03012/) (2016)
- [ChatDoctor: A Medical Chat Model Fine-Tuned on a Large Language Model Meta-AI (LLaMA) Using Medical Domain Knowledge](https://mlsanity.com/paper/2303.14070/) (2023)
- [MedAlpaca -- An Open-Source Collection of Medical Conversational AI Models and Training Data](https://mlsanity.com/paper/2304.08247/) (2023)
- [AgentClinic: a multimodal agent benchmark to evaluate AI in simulated clinical environments](https://mlsanity.com/paper/2405.07960/) (2024)
- [Evaluating Deep Neural Networks Trained on Clinical Images in Dermatology with the Fitzpatrick 17k Dataset](https://mlsanity.com/paper/2104.09957/) (2021)
- [MediQ: Question-Asking LLMs and a Benchmark for Reliable Interactive Clinical Reasoning](https://mlsanity.com/paper/2406.00922/) (2024)
- [Zhongjing: Enhancing the Chinese Medical Capabilities of Large Language Model through Expert Feedback and Real-world Multi-turn Dialogue](https://mlsanity.com/paper/2308.03549/) (2023)
- [AI Hospital: Benchmarking Large Language Models in a Multi-agent Medical Interaction Simulator](https://mlsanity.com/paper/2402.09742/) (2024)
- [MedExQA: Medical Question Answering Benchmark with Multiple Explanations](https://mlsanity.com/paper/2406.06331/) (2024)
- [NoteChat: A Dataset of Synthetic Doctor-Patient Conversations Conditioned on Clinical Notes](https://mlsanity.com/paper/2310.15959/) (2023)
- [A Benchmark for Automatic Medical Consultation System: Frameworks, Tasks and Datasets](https://mlsanity.com/paper/2204.08997/) (2022)
- [CLIPSyntel: CLIP and LLM Synergy for Multimodal Question Summarization in Healthcare](https://mlsanity.com/paper/2312.11541/) (2023)
- [K-QA: A Real-World Medical Q&A Benchmark](https://mlsanity.com/paper/2401.14493/) (2024)

## Built on by (most cited first, 16 of 16)

- [Perception, Reason, Think, and Plan: A Survey on Large Multimodal Reasoning Models](https://mlsanity.com/paper/2505.04921/) (2025)
- [MedDialogRubrics: A Comprehensive Benchmark and Evaluation Framework for Multi-turn Medical Consultations in Large Language Models](https://mlsanity.com/paper/2601.03023/) (2026)
- [Safe-LLaVA: A Privacy-Preserving Vision-Language Dataset and Benchmark for Biometric Safety](https://mlsanity.com/paper/2509.00192/) (2025)
- [MediSkill-Evo: Process-Constrained Self-Evolution for Evidence-Grounded Clinical Interaction](https://mlsanity.com/paper/2608.23397/) (2026)
- [Empowering Real-World: A Survey on the Technology, Practice, and Evaluation of LLM-driven Industry Agents](https://mlsanity.com/paper/2510.17491/) (2025)
- [MedInsightBench: Evaluating Medical Analytics Agents Through Multi-Step Insight Discovery in Multimodal Medical Data](https://mlsanity.com/paper/2512.13297/) (2025)
- [The Path to Self-Evolving Clinical Systems: Scaling Medical Agents from Assistance to Autonomy](https://mlsanity.com/paper/2607.11175/) (2026)
- [Aligning Clinical Needs and AI Capabilities: A Survey on LLMs for Medical Reasoning](https://mlsanity.com/paper/2607.07761/) (2026)
- [MentalHospital: A Virtual Environment for Evaluating Psychiatric Clinical Encounters](https://mlsanity.com/paper/2607.08257/) (2026)
- [Evaluating Medical LLMs by Levels of Autonomy: A Survey Moving from Benchmarks to Applications](https://mlsanity.com/paper/2510.17764/) (2025)
- [LLM-Guided Evolution for Medical Decision Pipelines](https://mlsanity.com/paper/2606.07342/) (2026)
- [IMCBench: A benchmark for multimodal LLMs in Image-grounded Medical Conversations](https://mlsanity.com/paper/2606.28556/) (2026)
- [MedRealMM: A Real-World Multimodal Benchmark for Chinese Online Medical Consultation](https://mlsanity.com/paper/2607.09142/) (2026)
- [ELICITED: EHR-grounded Longitudinal Interactive Conversations for Information-seeking Triage Evaluation and Decision-making](https://mlsanity.com/paper/2608.09024/) (2026)
- [A Source-Grounded Framework for Constructing and Evaluating Progressive Multimodal Diagnostic Dialogues from Clinical Case Reports](https://mlsanity.com/paper/2608.22713/) (2026)
- [MedRoundsQA: A Persona and Difficulty Aware Evaluation for Multi-Turn Medical Consultations](https://mlsanity.com/paper/2609.12851/) (2026)

## Abstract (arXiv)

Though Large Vision-Language Models (LVLMs) are being actively explored in medicine, their ability to conduct complex real-world telemedicine consultations combining accurate diagnosis with professional dialogue remains underexplored. This paper presents 3MDBench (Medical Multimodal Multi-agent Dialogue Benchmark), an open-source framework for simulating and evaluating LVLM-driven telemedical consultations. 3MDBench simulates patient variability through temperament-based Patient Agent and evaluates diagnostic accuracy and dialogue quality via Assessor Agent. It includes 2996 cases across 34 diagnoses from real-world telemedicine interactions, combining textual and image-based data. The experimental study compares diagnostic strategies for widely used open and closed-source LVLMs. We demonstrate that multimodal dialogue with internal reasoning improves F1 score by 6.5% over non-dialogue settings, highlighting the importance of context-aware, information-seeking questioning. Moreover, injecting predictions from a diagnostic convolutional neural network into the LVLM's context boosts F1 by up to 20%. Source code is available at https://github.com/univanxx/3mdbench.