# CRAB: A Benchmark for Evaluating Curation of Retrieval-Augmented LLMs in Biomedicine

arXiv: https://arxiv.org/abs/2504.12342 · HTML: https://mlsanity.com/paper/2504.12342/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Medical and biomedical RAG, one of 15 directions in Retrieval-augmented generation.
- Builds on 39 of its 46 references that are in the map.
- First posted on arXiv 15 Apr 2025.

## Placed in

- Retrieval-augmented generation / [Medical and biomedical RAG](https://mlsanity.com/rag/medical-and-biomedical-rag/)

## Builds on (most cited first, 30 of 39)

- [The Llama 3 Herd of Models](https://mlsanity.com/paper/2407.21783/) (2024)
- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [Measuring Massive Multitask Language Understanding](https://mlsanity.com/paper/2009.03300/) (2020)
- [Lost in the Middle: How Language Models Use Long Contexts](https://mlsanity.com/paper/2307.03172/) (2023)
- [Gemini 1.5: Unlocking multimodal understanding across millions of tokens of context](https://mlsanity.com/paper/2403.05530/) (2024)
- [Retrieval-Augmented Generation for Large Language Models: A Survey](https://mlsanity.com/paper/2312.10997/) (2023)
- [REALM: Retrieval-Augmented Language Model Pre-Training](https://mlsanity.com/paper/2002.08909/) (2020)
- [Large Language Models Encode Clinical Knowledge](https://mlsanity.com/paper/2212.13138/) (2022)
- [A Survey on Hallucination in Large Language Models: Principles, Taxonomy, Challenges, and Open Questions](https://mlsanity.com/paper/2311.05232/) (2023)
- [What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Exams](https://mlsanity.com/paper/2009.13081/) (2020)
- [Improving language models by retrieving from trillions of tokens](https://mlsanity.com/paper/2112.04426/) (2021)
- [PubMedQA: A Dataset for Biomedical Research Question Answering](https://mlsanity.com/paper/1909.06146/) (2019)
- [Atlas: Few-shot Learning with Retrieval Augmented Language Models](https://mlsanity.com/paper/2208.03299/) (2022)
- [A Multitask, Multilingual, Multimodal Evaluation of ChatGPT on Reasoning, Hallucination, and Interactivity](https://mlsanity.com/paper/2302.04023/) (2023)
- [Capabilities of GPT-4 on Medical Challenge Problems](https://mlsanity.com/paper/2303.13375/) (2023)
- [Enabling Large Language Models to Generate Text with Citations](https://mlsanity.com/paper/2305.14627/) (2023)
- [How Close is ChatGPT to Human Experts? Comparison Corpus, Evaluation, and Detection](https://mlsanity.com/paper/2301.07597/) (2023)
- [Ragas: Automated Evaluation of Retrieval Augmented Generation](https://mlsanity.com/paper/2309.15217/) (2023)
- [Benchmarking Retrieval-Augmented Generation for Medicine](https://mlsanity.com/paper/2402.13178/) (2024)
- [Benchmarking Large Language Models in Retrieval-Augmented Generation](https://mlsanity.com/paper/2309.01431/) (2023)
- [Teaching language models to support answers with verified quotes](https://mlsanity.com/paper/2203.11147/) (2022)
- [A Comprehensive Survey of Hallucination Mitigation Techniques in Large Language Models](https://mlsanity.com/paper/2401.01313/) (2024)
- [ARES: An Automated Evaluation Framework for Retrieval-Augmented Generation Systems](https://mlsanity.com/paper/2311.09476/) (2023)
- [Survey on Factuality in Large Language Models: Knowledge, Retrieval and Domain-Specificity](https://mlsanity.com/paper/2310.07521/) (2023)
- [Large Language Models with Controllable Working Memory](https://mlsanity.com/paper/2211.05110/) (2022)
- [The Curious Case of Hallucinations in Neural Machine Translation](https://mlsanity.com/paper/2104.06683/) (2021)
- [PaperQA: Retrieval-Augmented Generative Agent for Scientific Research](https://mlsanity.com/paper/2312.07559/) (2023)
- [Evaluation of Retrieval-Augmented Generation: A Survey](https://mlsanity.com/paper/2405.07437/) (2024)
- [Rethinking with Retrieval: Faithful Large Language Model Inference](https://mlsanity.com/paper/2301.00303/) (2022)
- [Almanac: Retrieval-Augmented Language Models for Clinical Medicine](https://mlsanity.com/paper/2303.01229/) (2023)

## Abstract (arXiv)

Recent development in Retrieval-Augmented Large Language Models (LLMs) have shown great promise in biomedical applications. How ever, a critical gap persists in reliably evaluating their curation ability the process by which models select and integrate relevant references while filtering out noise. To address this, we introduce the benchmark for Curation of Retrieval-Augmented LLMs in Biomedicine (CRAB), the first multilingual benchmark tailored for evaluating the biomedical curation of retrieval-augmented LLMs, available in English, French, German and Chinese. By incorporating a novel citation-based evaluation metric, CRAB quantifies the curation performance of retrieval-augmented LLMs in biomedicine. Experimental results reveal significant discrepancies in the curation performance of mainstream LLMs, underscoring the urgent need to improve it in the domain of biomedicine. Our dataset is available at https://huggingface.co/datasets/zhm0/CRAB.