# Flyweight FLIM Networks for Salient Object Detection in Biomedical Images

arXiv: https://arxiv.org/abs/2504.11112 · HTML: https://mlsanity.com/paper/2504.11112/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 11 of its 29 references that are in the map.
- First posted on arXiv 15 Apr 2025.

## Builds on (most cited first, 11 of 11)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [MobileNetV2: Inverted Residuals and Linear Bottlenecks](https://mlsanity.com/paper/1801.04381/) (2018)
- [Green AI](https://mlsanity.com/paper/1907.10597/) (2019)
- [Pruning neural networks without any data by iteratively conserving synaptic flow](https://mlsanity.com/paper/2006.05467/) (2020)
- [U2-Net: Going Deeper with Nested U-Structure for Salient Object Detection](https://mlsanity.com/paper/2005.09007/) (2020)
- [A Simple Pooling-Based Design for Real-Time Salient Object Detection](https://mlsanity.com/paper/1904.09569/) (2019)
- [Salient Object Detection in the Deep Learning Era: An In-Depth Survey](https://mlsanity.com/paper/1904.09146/) (2019)
- [Salient Object Detection: A Survey](https://mlsanity.com/paper/1411.5878/) (2014)
- [Highly Efficient Salient Object Detection with 100K Parameters](https://mlsanity.com/paper/2003.05643/) (2020)
- [Learning Uncertain Convolutional Features for Accurate Saliency Detection](https://mlsanity.com/paper/1708.02031/) (2017)
- [Building Brain Tumor Segmentation Networks with User-Assisted Filter Estimation and Selection](https://mlsanity.com/paper/2403.12748/) (2024)

## Abstract (arXiv)

Salient Object Detection (SOD) with deep learning often requires substantial computational resources and large annotated datasets, making it impractical for resource-constrained applications. Lightweight models address computational demands but typically strive in complex and scarce labeled-data scenarios. Feature Learning from Image Markers (FLIM) learns an encoder's convolutional kernels among image patches extracted from discriminative regions marked on a few representative images, dismissing large annotated datasets, pretraining, and backpropagation. Such a methodology exploits information redundancy commonly found in biomedical image applications. This study presents methods to learn dilated-separable convolutional kernels and multi-dilation layers without backpropagation for FLIM networks. It also proposes a novel network simplification method to reduce kernel redundancy and encoder size. By combining a FLIM encoder with an adaptive decoder, a concept recently introduced to estimate a pointwise convolution per image, this study presents very efficient (named flyweight) SOD models for biomedical images. Experimental results in challenging datasets demonstrate superior efficiency and effectiveness to lightweight models. By requiring significantly fewer parameters and floating-point operations, the results show competitive effectiveness to heavyweight models. These advances highlight the potential of FLIM networks for data-limited and resource-constrained applications with information redundancy.