# InterAnimate: Taming Region-aware Diffusion Model for Realistic Human Interaction Animation

arXiv: https://arxiv.org/abs/2504.10905 · HTML: https://mlsanity.com/paper/2504.10905/

## Key facts

- Cited by 4 papers in the map (data through 14 Oct 2026).
- Placed in Video generation, one of 14 directions in Diffusion models.
- Builds on 56 of its 71 references that are in the map.
- First posted on arXiv 15 Apr 2025.

## Placed in

- Diffusion models / [Video generation](https://mlsanity.com/diffusion/video-generation/)

## Builds on (most cited first, 30 of 56)

- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [The Unreasonable Effectiveness of Deep Features as a Perceptual Metric](https://mlsanity.com/paper/1801.03924/) (2018)
- [BLIP-2: Bootstrapping Language-Image Pre-training with Frozen Image Encoders and Large Language Models](https://mlsanity.com/paper/2301.12597/) (2023)
- [Adding Conditional Control to Text-to-Image Diffusion Models](https://mlsanity.com/paper/2302.05543/) (2023)
- [DreamFusion: Text-to-3D using 2D Diffusion](https://mlsanity.com/paper/2209.14988/) (2022)
- [Stable Video Diffusion: Scaling Latent Video Diffusion Models to Large Datasets](https://mlsanity.com/paper/2311.15127/) (2023)
- [Make-A-Video: Text-to-Video Generation without Text-Video Data](https://mlsanity.com/paper/2209.14792/) (2022)
- [HunyuanVideo: A Systematic Framework For Large Video Generative Models](https://mlsanity.com/paper/2412.03603/) (2024)
- [Align your Latents: High-Resolution Video Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2304.08818/) (2023)
- [Towards Accurate Generative Models of Video: A New Metric & Challenges](https://mlsanity.com/paper/1812.01717/) (2018)
- [Tune-A-Video: One-Shot Tuning of Image Diffusion Models for Text-to-Video Generation](https://mlsanity.com/paper/2212.11565/) (2022)
- [Animate Anyone: Consistent and Controllable Image-to-Video Synthesis for Character Animation](https://mlsanity.com/paper/2311.17117/) (2023)
- [Text2Video-Zero: Text-to-Image Diffusion Models are Zero-Shot Video Generators](https://mlsanity.com/paper/2303.13439/) (2023)
- [T2M-GPT: Generating Human Motion from Textual Descriptions with Discrete Representations](https://mlsanity.com/paper/2301.06052/) (2023)
- [Latent Video Diffusion Models for High-Fidelity Long Video Generation](https://mlsanity.com/paper/2211.13221/) (2022)
- [MagicAnimate: Temporally Consistent Human Image Animation using Diffusion Model](https://mlsanity.com/paper/2311.16498/) (2023)
- [Follow Your Pose: Pose-Guided Text-to-Video Generation using Pose-Free Videos](https://mlsanity.com/paper/2304.01186/) (2023)
- [Effective Whole-body Pose Estimation with Two-stages Distillation](https://mlsanity.com/paper/2307.15880/) (2023)
- [Open-Sora Plan: Open-Source Large Video Generation Model](https://mlsanity.com/paper/2412.00131/) (2024)
- [Champ: Controllable and Consistent Human Image Animation with 3D Parametric Guidance](https://mlsanity.com/paper/2403.14781/) (2024)
- [Motion Representations for Articulated Animation](https://mlsanity.com/paper/2104.11280/) (2021)
- [Rerender A Video: Zero-Shot Text-Guided Video-to-Video Translation](https://mlsanity.com/paper/2306.07954/) (2023)
- [Object Motion Guided Human Motion Synthesis](https://mlsanity.com/paper/2309.16237/) (2023)
- [LivePortrait: Efficient Portrait Animation with Stitching and Retargeting Control](https://mlsanity.com/paper/2407.03168/) (2024)
- [Taming Rectified Flow for Inversion and Editing](https://mlsanity.com/paper/2411.04746/) (2024)
- [MimicMotion: High-Quality Human Motion Video Generation with Confidence-aware Pose Guidance](https://mlsanity.com/paper/2406.19680/) (2024)
- [InterDiff: Generating 3D Human-Object Interactions with Physics-Informed Diffusion](https://mlsanity.com/paper/2308.16905/) (2023)
- [Follow-Your-Emoji: Fine-Controllable and Expressive Freestyle Portrait Animation](https://mlsanity.com/paper/2406.01900/) (2024)
- [DisCo: Disentangled Control for Realistic Human Dance Generation](https://mlsanity.com/paper/2307.00040/) (2023)
- [IMos: Intent-Driven Full-Body Motion Synthesis for Human-Object Interactions](https://mlsanity.com/paper/2212.07555/) (2022)

## Built on by (most cited first, 4 of 4)

- [PreciseCache: Precise Feature Caching for Efficient and High-fidelity Video Generation](https://mlsanity.com/paper/2603.00976/) (2026)
- [LottieGPT: Tokenizing Vector Animation for Autoregressive Generation](https://mlsanity.com/paper/2604.11792/) (2026)
- [Creative4U: MLLMs-based Advertising Creative Image Selector with Comparative Reasoning](https://mlsanity.com/paper/2508.12628/) (2025)
- [Learning from Label Proportions with Dual-proportion Constraints](https://mlsanity.com/paper/2603.21153/) (2026)

## Abstract (arXiv)

Recent video generation research has focused heavily on isolated actions, leaving interactive motions-such as hand-face interactions-largely unexamined. These interactions are essential for emerging biometric authentication systems, which rely on interactive motion-based anti-spoofing approaches. From a security perspective, there is a growing need for large-scale, high-quality interactive videos to train and strengthen authentication models. In this work, we introduce a novel paradigm for animating realistic hand-face interactions. Our approach simultaneously learns spatio-temporal contact dynamics and biomechanically plausible deformation effects, enabling natural interactions where hand movements induce anatomically accurate facial deformations while maintaining collision-free contact. To facilitate this research, we present InterHF, a large-scale hand-face interaction dataset featuring 18 interaction patterns and 90,000 annotated videos. Additionally, we propose InterAnimate, a region-aware diffusion model designed specifically for interaction animation. InterAnimate leverages learnable spatial and temporal latents to effectively capture dynamic interaction priors and integrates a region-aware interaction mechanism that injects these priors into the denoising process. To the best of our knowledge, this work represents the first large-scale effort to systematically study human hand-face interactions. Qualitative and quantitative results show InterAnimate produces highly realistic animations, setting a new benchmark. Code and data will be made public to advance research.