# S^4M: Boosting Semi-Supervised Instance Segmentation with SAM

arXiv: https://arxiv.org/abs/2504.05301 · HTML: https://mlsanity.com/paper/2504.05301/

## Key facts

- Cited by 5 papers in the map (data through 14 Oct 2026).
- Builds on 59 of its 67 references that are in the map.
- First posted on arXiv 7 Apr 2025.

## Builds on (most cited first, 30 of 59)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Distilling the Knowledge in a Neural Network](https://mlsanity.com/paper/1503.02531/) (2015)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [DINOv2: Learning Robust Visual Features without Supervision](https://mlsanity.com/paper/2304.07193/) (2023)
- [Masked Autoencoders Are Scalable Vision Learners](https://mlsanity.com/paper/2111.06377/) (2021)
- [Mask R-CNN](https://mlsanity.com/paper/1703.06870/) (2017)
- [mixup: Beyond Empirical Risk Minimization](https://mlsanity.com/paper/1710.09412/) (2017)
- [The Cityscapes Dataset for Semantic Urban Scene Understanding](https://mlsanity.com/paper/1604.01685/) (2016)
- [CutMix: Regularization Strategy to Train Strong Classifiers with Localizable Features](https://mlsanity.com/paper/1905.04899/) (2019)
- [SAM 2: Segment Anything in Images and Videos](https://mlsanity.com/paper/2408.00714/) (2024)
- [Masked-attention Mask Transformer for Universal Image Segmentation](https://mlsanity.com/paper/2112.01527/) (2021)
- [V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentation](https://mlsanity.com/paper/1606.04797/) (2016)
- [RandAugment: Practical automated data augmentation with a reduced search space](https://mlsanity.com/paper/1909.13719/) (2019)
- [FixMatch: Simplifying Semi-Supervised Learning with Consistency and Confidence](https://mlsanity.com/paper/2001.07685/) (2020)
- [FitNets: Hints for Thin Deep Nets](https://mlsanity.com/paper/1412.6550/) (2014)
- [Improved Regularization of Convolutional Neural Networks with Cutout](https://mlsanity.com/paper/1708.04552/) (2017)
- [Per-Pixel Classification is Not All You Need for Semantic Segmentation](https://mlsanity.com/paper/2107.06278/) (2021)
- [Paying More Attention to Attention: Improving the Performance of Convolutional Neural Networks via Attention Transfer](https://mlsanity.com/paper/1612.03928/) (2016)
- [Grounded SAM: Assembling Open-World Models for Diverse Visual Tasks](https://mlsanity.com/paper/2401.14159/) (2024)
- [Relational Knowledge Distillation](https://mlsanity.com/paper/1904.05068/) (2019)
- [Panoptic Segmentation](https://mlsanity.com/paper/1801.00868/) (2018)
- [Simple Copy-Paste is a Strong Data Augmentation Method for Instance Segmentation](https://mlsanity.com/paper/2012.07177/) (2020)
- [Extract Free Dense Labels from CLIP](https://mlsanity.com/paper/2112.01071/) (2021)
- [Deep ViT Features as Dense Visual Descriptors](https://mlsanity.com/paper/2112.05814/) (2021)
- [Hiera: A Hierarchical Vision Transformer without the Bells-and-Whistles](https://mlsanity.com/paper/2306.00989/) (2023)
- [Structured Knowledge Distillation for Dense Prediction](https://mlsanity.com/paper/1903.04197/) (2019)
- [Personalize Segment Anything Model with One Shot](https://mlsanity.com/paper/2305.03048/) (2023)
- [Track Anything: Segment Anything Meets Videos](https://mlsanity.com/paper/2304.11968/) (2023)

## Built on by (most cited first, 5 of 5)

- [CAST: Contrastive Adaptation and Distillation for Semi-Supervised Instance Segmentation](https://mlsanity.com/paper/2505.21904/) (2025)
- [Boosting Overlapping Organoid Instance Segmentation Using Pseudo-Label Unmixing and Synthesis-Assisted Learning](https://mlsanity.com/paper/2601.06642/) (2026)
- [Exclusivity-Guided Mask Learning for Semi-Supervised Crowd Instance Segmentation and Counting](https://mlsanity.com/paper/2603.16241/) (2026)
- [Training a Student Expert via Semi-Supervised Foundation Model Distillation](https://mlsanity.com/paper/2604.03841/) (2026)
- [Instance-Aware Knowledge Distillation for Semi-Supervised Learning of an On-Board Multi-Task Dense Prediction Model for Collision Avoidance System](https://mlsanity.com/paper/2606.16414/) (2026)

## Abstract (arXiv)

Semi-supervised instance segmentation poses challenges due to limited labeled data, causing difficulties in accurately localizing distinct object instances. Current teacher-student frameworks still suffer from performance constraints due to unreliable pseudo-label quality stemming from limited labeled data. While the Segment Anything Model (SAM) offers robust segmentation capabilities at various granularities, directly applying SAM to this task introduces challenges such as class-agnostic predictions and potential over-segmentation. To address these complexities, we carefully integrate SAM into the semi-supervised instance segmentation framework, developing a novel distillation method that effectively captures the precise localization capabilities of SAM without compromising semantic recognition. Furthermore, we incorporate pseudo-label refinement as well as a specialized data augmentation with the refined pseudo-labels, resulting in superior performance. We establish state-of-the-art performance, and provide comprehensive experiments and ablation studies to validate the effectiveness of our proposed approach.