# A Comparative Study of Explainable AI Methods: Model-Agnostic vs. Model-Specific Approaches

arXiv: https://arxiv.org/abs/2504.04276 · HTML: https://mlsanity.com/paper/2504.04276/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 6 of its 9 references that are in the map.
- First posted on arXiv 5 Apr 2025.

## Builds on (most cited first, 6 of 6)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Grad-CAM: Visual Explanations from Deep Networks via Gradient-based Localization](https://mlsanity.com/paper/1610.02391/) (2016)
- [A Unified Approach to Interpreting Model Predictions](https://mlsanity.com/paper/1705.07874/) (2017)
- ["Why Should I Trust You?": Explaining the Predictions of Any Classifier](https://mlsanity.com/paper/1602.04938/) (2016)
- [Towards A Rigorous Science of Interpretable Machine Learning](https://mlsanity.com/paper/1702.08608/) (2017)
- [Striving for Simplicity: The All Convolutional Net](https://mlsanity.com/paper/1412.6806/) (2014)

## Built on by (most cited first, 1 of 1)

- [EVO-LRP: Evolutionary Optimization of LRP for Interpretable Model Explanations](https://mlsanity.com/paper/2509.23585/) (2025)

## Abstract (arXiv)

This paper compares model-agnostic and model-specific approaches to explainable AI (XAI) in deep learning image classification. I examine how LIME and SHAP (model-agnostic methods) differ from Grad-CAM and Guided Backpropagation (model-specific methods) when interpreting ResNet50 predictions across diverse image categories. Through extensive testing with various species from dogs and birds to insects I found that each method reveals different aspects of the models decision-making process. Model-agnostic techniques provide broader feature attribution that works across different architectures, while model-specific approaches excel at highlighting precise activation regions with greater computational efficiency. My analysis shows there is no "one-size-fits-all" solution for model interpretability. Instead, combining multiple XAI methods offers the most comprehensive understanding of complex models particularly valuable in high-stakes domains like healthcare, autonomous vehicles, and financial services where transparency is crucial. This comparative framework provides practical guidance for selecting appropriate interpretability techniques based on specific application needs and computational constraints.