# Survey and Experiments on Mental Disorder Detection via Social Media: From Large Language Models and RAG to Agents

arXiv: https://arxiv.org/abs/2504.02800 · HTML: https://mlsanity.com/paper/2504.02800/

## Key facts

- Cited by 6 papers in the map (data through 14 Oct 2026).
- Placed in Medical and scientific domain agents, one of 16 directions in LLM agents and tool use.
- Builds on 92 of its 250 references that are in the map.
- First posted on arXiv 3 Apr 2025.

## Placed in

- LLM agents and tool use / [Medical and scientific domain agents](https://mlsanity.com/agents/medical-and-scientific-domain-agents/)

## Builds on (most cited first, 30 of 92)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [Training language models to follow instructions with human feedback](https://mlsanity.com/paper/2203.02155/) (2022)
- [The Llama 3 Herd of Models](https://mlsanity.com/paper/2407.21783/) (2024)
- [LLaMA: Open and Efficient Foundation Language Models](https://mlsanity.com/paper/2302.13971/) (2023)
- [RoBERTa: A Robustly Optimized BERT Pretraining Approach](https://mlsanity.com/paper/1907.11692/) (2019)
- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [Visual Instruction Tuning](https://mlsanity.com/paper/2304.08485/) (2023)
- [DeepSeek-R1: Incentivizing Reasoning Capability in LLMs via Reinforcement Learning](https://mlsanity.com/paper/2501.12948/) (2025)
- [BART: Denoising Sequence-to-Sequence Pre-training for Natural Language Generation, Translation, and Comprehension](https://mlsanity.com/paper/1910.13461/) (2019)
- [XGBoost: A Scalable Tree Boosting System](https://mlsanity.com/paper/1603.02754/) (2016)
- [GPT-4o System Card](https://mlsanity.com/paper/2410.21276/) (2024)
- [DistilBERT, a distilled version of BERT: smaller, faster, cheaper and lighter](https://mlsanity.com/paper/1910.01108/) (2019)
- [Self-Instruct: Aligning Language Models with Self-Generated Instructions](https://mlsanity.com/paper/2212.10560/) (2022)
- [Retrieval-Augmented Generation for Large Language Models: A Survey](https://mlsanity.com/paper/2312.10997/) (2023)
- [Mixtral of Experts](https://mlsanity.com/paper/2401.04088/) (2024)
- [A Survey on Hallucination in Large Language Models: Principles, Taxonomy, Challenges, and Open Questions](https://mlsanity.com/paper/2311.05232/) (2023)
- [DeepSeek-V2: A Strong, Economical, and Efficient Mixture-of-Experts Language Model](https://mlsanity.com/paper/2405.04434/) (2024)
- [M3-Embedding: Multi-Linguality, Multi-Functionality, Multi-Granularity Text Embeddings Through Self-Knowledge Distillation](https://mlsanity.com/paper/2402.03216/) (2024)
- [Publicly Available Clinical BERT Embeddings](https://mlsanity.com/paper/1904.03323/) (2019)
- [DeepSeekMoE: Towards Ultimate Expert Specialization in Mixture-of-Experts Language Models](https://mlsanity.com/paper/2401.06066/) (2024)
- [Vision-Language Models for Vision Tasks: A Survey](https://mlsanity.com/paper/2304.00685/) (2023)
- [DeepSeek-VL: Towards Real-World Vision-Language Understanding](https://mlsanity.com/paper/2403.05525/) (2024)
- [Retrieval Augmentation Reduces Hallucination in Conversation](https://mlsanity.com/paper/2104.07567/) (2021)
- [A Comprehensive Overview of Large Language Models](https://mlsanity.com/paper/2307.06435/) (2023)
- [A Survey on the Memory Mechanism of Large Language Model based Agents](https://mlsanity.com/paper/2404.13501/) (2024)
- [Active Retrieval Augmented Generation](https://mlsanity.com/paper/2305.06983/) (2023)
- [Universal Sentence Encoder](https://mlsanity.com/paper/1803.11175/) (2018)

## Built on by (most cited first, 6 of 6)

- [Beyond Empathy: Integrating Diagnostic and Therapeutic Reasoning with Large Language Models for Mental Health Counseling](https://mlsanity.com/paper/2505.15715/) (2025)
- [Menta: A Small Language Model for On-Device Mental Health Prediction](https://mlsanity.com/paper/2512.02716/) (2025)
- [Dep-LLM: Training-Free Depression Diagnosis via Evidence-Guided Structured Multi-factor with Reliable LLM Reasoning](https://mlsanity.com/paper/2606.10796/) (2026)
- [Decoding Neural Emotion Patterns through Large Language Model Embeddings](https://mlsanity.com/paper/2508.09337/) (2025)
- [Towards Efficient and Robust Linguistic Emotion Diagnosis for Mental Health via Multi-Agent Instruction Refinement](https://mlsanity.com/paper/2601.13481/) (2026)
- [From Pattern Recognizers to Personalized Companions: A Survey of Large Language Models in Mental Health](https://mlsanity.com/paper/2609.25186/) (2026)

## Abstract (arXiv)

Mental disorders represent a critical global health challenge, and social media is increasingly viewed as a vital resource for real-time digital phenotyping and intervention. To leverage this data, large language models (LLMs) have been introduced, offering stronger semantic understanding and reasoning than traditional deep learning, thereby enhancing the explainability of detection results. Despite the growing prominence of LLMs in this field, there is a scarcity of scholarly works that systematically synthesize how advanced enhancement techniques, specifically Retrieval-Augmented Generation (RAG) and Agentic systems, can be utilized to address these reliability and reasoning limitations. Here, we systematically survey the evolving landscape of LLM-based methods for social media mental disorder analysis, spanning standard pre-trained language models, RAG to mitigate hallucinations and contextual gaps, and agentic systems for autonomous reasoning and multi-step intervention. We organize existing work by technical paradigm and clinical target, extending beyond common internalizing disorders to include psychotic disorders and externalizing behaviors. Additionally, the paper comprehensively evaluates the performance of LLMs, including the impact of RAG, across various tasks. This work establishes a unified benchmark for the field, paving the way for the development of trustworthy, autonomous AI systems that can deliver precise and explainable mental health support.