# Domain Guidance: A Simple Transfer Approach for a Pre-trained Diffusion Model

arXiv: https://arxiv.org/abs/2504.01521 · HTML: https://mlsanity.com/paper/2504.01521/

## Key facts

- Cited by 8 papers in the map (data through 14 Oct 2026).
- Placed in Diffusion foundations and sampling, one of 14 directions in Diffusion models.
- Builds on 31 of its 41 references that are in the map.
- First posted on arXiv 2 Apr 2025.

## Placed in

- Diffusion models / [Diffusion foundations and sampling](https://mlsanity.com/diffusion/diffusion-foundations-and-sampling/)

## Builds on (most cited first, 30 of 31)

- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [Denoising Diffusion Implicit Models](https://mlsanity.com/paper/2010.02502/) (2020)
- [Score-Based Generative Modeling through Stochastic Differential Equations](https://mlsanity.com/paper/2011.13456/) (2020)
- [Diffusion Models Beat GANs on Image Synthesis](https://mlsanity.com/paper/2105.05233/) (2021)
- [Photorealistic Text-to-Image Diffusion Models with Deep Language Understanding](https://mlsanity.com/paper/2205.11487/) (2022)
- [Scalable Diffusion Models with Transformers](https://mlsanity.com/paper/2212.09748/) (2022)
- [Classifier-Free Diffusion Guidance](https://mlsanity.com/paper/2207.12598/) (2022)
- [Adding Conditional Control to Text-to-Image Diffusion Models](https://mlsanity.com/paper/2302.05543/) (2023)
- [Parameter-Efficient Transfer Learning for NLP](https://mlsanity.com/paper/1902.00751/) (2019)
- [Scaling Rectified Flow Transformers for High-Resolution Image Synthesis](https://mlsanity.com/paper/2403.03206/) (2024)
- [Generative Modeling by Estimating Gradients of the Data Distribution](https://mlsanity.com/paper/1907.05600/) (2019)
- [Improved Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2102.09672/) (2021)
- [Elucidating the Design Space of Diffusion-Based Generative Models](https://mlsanity.com/paper/2206.00364/) (2022)
- [Stable Video Diffusion: Scaling Latent Video Diffusion Models to Large Datasets](https://mlsanity.com/paper/2311.15127/) (2023)
- [Learning without Forgetting](https://mlsanity.com/paper/1606.09282/) (2016)
- [Video Diffusion Models](https://mlsanity.com/paper/2204.03458/) (2022)
- [BitFit: Simple Parameter-efficient Fine-tuning for Transformer-based Masked Language-models](https://mlsanity.com/paper/2106.10199/) (2021)
- [How transferable are features in deep neural networks?](https://mlsanity.com/paper/1411.1792/) (2014)
- [Improved Precision and Recall Metric for Assessing Generative Models](https://mlsanity.com/paper/1904.06991/) (2019)
- [Fine-Tuning can Distort Pretrained Features and Underperform Out-of-Distribution](https://mlsanity.com/paper/2202.10054/) (2022)
- [Analyzing and Improving the Training Dynamics of Diffusion Models](https://mlsanity.com/paper/2312.02696/) (2023)
- [Guiding a Diffusion Model with a Bad Version of Itself](https://mlsanity.com/paper/2406.02507/) (2024)
- [Applying Guidance in a Limited Interval Improves Sample and Distribution Quality in Diffusion Models](https://mlsanity.com/paper/2404.07724/) (2024)
- [Exposing flaws of generative model evaluation metrics and their unfair treatment of diffusion models](https://mlsanity.com/paper/2306.04675/) (2023)
- [Score Approximation, Estimation and Distribution Recovery of Diffusion Models on Low-Dimensional Data](https://mlsanity.com/paper/2302.07194/) (2023)
- [DiffFit: Unlocking Transferability of Large Diffusion Models via Simple Parameter-Efficient Fine-Tuning](https://mlsanity.com/paper/2304.06648/) (2023)
- [Maximum-Entropy Fine-Grained Classification](https://mlsanity.com/paper/1809.05934/) (2018)
- [The ArtBench Dataset: Benchmarking Generative Models with Artworks](https://mlsanity.com/paper/2206.11404/) (2022)
- [Minimax Optimality of Score-based Diffusion Models: Beyond the Density Lower Bound Assumptions](https://mlsanity.com/paper/2402.15602/) (2024)

## Built on by (most cited first, 8 of 8)

- [AudioMoG: Guiding Audio Generation with Mixture-of-Guidance](https://mlsanity.com/paper/2509.23727/) (2025)
- [Inference-Time Alignment for Diffusion Models via Variationally Stable Doob's Matching](https://mlsanity.com/paper/2601.06514/) (2026)
- [DogFit: Domain-guided Fine-tuning for Efficient Transfer Learning of Diffusion Models](https://mlsanity.com/paper/2508.05685/) (2025)
- [MMD Guidance: Training-Free Distribution Adaptation for Diffusion Models via Maximum Mean Discrepancy Guidance](https://mlsanity.com/paper/2601.08379/) (2026)
- [Mitigating the Noise Shift for Denoising Generative Models via Noise Awareness Guidance](https://mlsanity.com/paper/2510.12497/) (2025)
- [SGN: A Similarity-based Generative Network for Data Generation under Distribution Shift](https://mlsanity.com/paper/2607.18072/) (2026)
- [Continuous Adversarial MeanFlow Transfer](https://mlsanity.com/paper/2608.19540/) (2026)
- [NowcastDiT: Diffusion Transformers are Effective Precipitation Nowcasters](https://mlsanity.com/paper/2609.37038/) (2026)

## Abstract (arXiv)

Recent advancements in diffusion models have revolutionized generative modeling. However, the impressive and vivid outputs they produce often come at the cost of significant model scaling and increased computational demands. Consequently, building personalized diffusion models based on off-the-shelf models has emerged as an appealing alternative. In this paper, we introduce a novel perspective on conditional generation for transferring a pre-trained model. From this viewpoint, we propose *Domain Guidance*, a straightforward transfer approach that leverages pre-trained knowledge to guide the sampling process toward the target domain. Domain Guidance shares a formulation similar to advanced classifier-free guidance, facilitating better domain alignment and higher-quality generations. We provide both empirical and theoretical analyses of the mechanisms behind Domain Guidance. Our experimental results demonstrate its substantial effectiveness across various transfer benchmarks, achieving over a 19.6% improvement in FID and a 23.4% improvement in FDDINOv2 compared to standard fine-tuning. Notably, existing fine-tuned models can seamlessly integrate Domain Guidance to leverage these benefits, without additional training.