# Biomedical Question Answering via Multi-Level Summarization on a Local Knowledge Graph

arXiv: https://arxiv.org/abs/2504.01309 · HTML: https://mlsanity.com/paper/2504.01309/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Medical and biomedical RAG, one of 15 directions in Retrieval-augmented generation.
- Builds on 16 of its 25 references that are in the map.
- First posted on arXiv 2 Apr 2025.

## Placed in

- Retrieval-augmented generation / [Medical and biomedical RAG](https://mlsanity.com/rag/medical-and-biomedical-rag/)

## Builds on (most cited first, 16 of 16)

- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [Measuring Massive Multitask Language Understanding](https://mlsanity.com/paper/2009.03300/) (2020)
- [Retrieval-Augmented Generation for Large Language Models: A Survey](https://mlsanity.com/paper/2312.10997/) (2023)
- [From Local to Global: A Graph RAG Approach to Query-Focused Summarization](https://mlsanity.com/paper/2404.16130/) (2024)
- [What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Exams](https://mlsanity.com/paper/2009.13081/) (2020)
- [PubMedQA: A Dataset for Biomedical Research Question Answering](https://mlsanity.com/paper/1909.06146/) (2019)
- [RAPTOR: Recursive Abstractive Processing for Tree-Organized Retrieval](https://mlsanity.com/paper/2401.18059/) (2024)
- [Precise Zero-Shot Dense Retrieval without Relevance Labels](https://mlsanity.com/paper/2212.10496/) (2022)
- [Benchmarking Retrieval-Augmented Generation for Medicine](https://mlsanity.com/paper/2402.13178/) (2024)
- [ScispaCy: Fast and Robust Models for Biomedical Natural Language Processing](https://mlsanity.com/paper/1902.07669/) (2019)
- [Knowledge Graph Prompting for Multi-Document Question Answering](https://mlsanity.com/paper/2308.11730/) (2023)
- [A Survey of Large Language Models in Medicine: Progress, Application, and Challenge](https://mlsanity.com/paper/2311.05112/) (2023)
- [From Isolated Conversations to Hierarchical Schemas: Dynamic Tree Memory Representation for LLMs](https://mlsanity.com/paper/2410.14052/) (2024)
- [Llama2Vec: Unsupervised Adaptation of Large Language Models for Dense Retrieval](https://mlsanity.com/paper/2312.15503/) (2023)
- [BiomedRAG: A Retrieval Augmented Large Language Model for Biomedicine](https://mlsanity.com/paper/2405.00465/) (2024)
- [Harnessing the Power of Semi-Structured Knowledge and LLMs with Triplet-Based Prefiltering for Question Answering](https://mlsanity.com/paper/2409.00861/) (2024)

## Abstract (arXiv)

In Question Answering (QA), Retrieval Augmented Generation (RAG) has revolutionized performance in various domains. However, how to effectively capture multi-document relationships, particularly critical for biomedical tasks, remains an open question. In this work, we propose a novel method that utilizes propositional claims to construct a local knowledge graph from retrieved documents. Summaries are then derived via layerwise summarization from the knowledge graph to contextualize a small language model to perform QA. We achieved comparable or superior performance with our method over RAG baselines on several biomedical QA benchmarks. We also evaluated each individual step of our methodology over a targeted set of metrics, demonstrating its effectiveness.