# AI-Assisted Colonoscopy: Polyp Detection and Segmentation using Foundation Models

arXiv: https://arxiv.org/abs/2503.24138 · HTML: https://mlsanity.com/paper/2503.24138/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 17 of its 37 references that are in the map.
- First posted on arXiv 31 Mar 2025.

## Builds on (most cited first, 17 of 17)

- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [Microsoft COCO: Common Objects in Context](https://mlsanity.com/paper/1405.0312/) (2014)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [DINOv2: Learning Robust Visual Features without Supervision](https://mlsanity.com/paper/2304.07193/) (2023)
- [Mask R-CNN](https://mlsanity.com/paper/1703.06870/) (2017)
- [You Only Look Once: Unified, Real-Time Object Detection](https://mlsanity.com/paper/1506.02640/) (2015)
- [Grounding DINO: Marrying DINO with Grounded Pre-Training for Open-Set Object Detection](https://mlsanity.com/paper/2303.05499/) (2023)
- [MMDetection: Open MMLab Detection Toolbox and Benchmark](https://mlsanity.com/paper/1906.07155/) (2019)
- [DINO: DETR with Improved DeNoising Anchor Boxes for End-to-End Object Detection](https://mlsanity.com/paper/2203.03605/) (2022)
- [YOLO-World: Real-Time Open-Vocabulary Object Detection](https://mlsanity.com/paper/2401.17270/) (2024)
- [Segment Anything in Medical Images](https://mlsanity.com/paper/2304.12306/) (2023)
- [Can Foundation Models Wrangle Your Data?](https://mlsanity.com/paper/2205.09911/) (2022)
- [Are Natural Domain Foundation Models Useful for Medical Image Classification?](https://mlsanity.com/paper/2310.19522/) (2023)
- [Polyp-SAM++: Can A Text Guided SAM Perform Better for Polyp Segmentation?](https://mlsanity.com/paper/2308.06623/) (2023)
- [3D TransUNet: Advancing Medical Image Segmentation through Vision Transformers](https://mlsanity.com/paper/2310.07781/) (2023)
- [SAM-EG: Segment Anything Model with Egde Guidance framework for efficient Polyp Segmentation](https://mlsanity.com/paper/2406.14819/) (2024)

## Abstract (arXiv)

In colonoscopy, 80% of the missed polyps could be detected with the help of Deep Learning models. In the search for algorithms capable of addressing this challenge, foundation models emerge as promising candidates. Their zero-shot or few-shot learning capabilities, facilitate generalization to new data or tasks without extensive fine-tuning. A concept that is particularly advantageous in the medical imaging domain, where large annotated datasets for traditional training are scarce. In this context, a comprehensive evaluation of foundation models for polyp segmentation was conducted, assessing both detection and delimitation. For the study, three different colonoscopy datasets have been employed to compare the performance of five different foundation models, DINOv2, YOLO-World, GroundingDINO, SAM and MedSAM, against two benchmark networks, YOLOv8 and Mask R-CNN. Results show that the success of foundation models in polyp characterization is highly dependent on domain specialization. For optimal performance in medical applications, domain-specific models are essential, and generic models require fine-tuning to achieve effective results. Through this specialization, foundation models demonstrated superior performance compared to state-of-the-art detection and segmentation models, with some models even excelling in zero-shot evaluation; outperforming fine-tuned models on unseen data.