# Unlocking the Potential of Past Research: Using Generative AI to Reconstruct Healthcare Simulation Models

arXiv: https://arxiv.org/abs/2503.21646 · HTML: https://mlsanity.com/paper/2503.21646/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 25 of its 81 references that are in the map.
- First posted on arXiv 27 Mar 2025.

## Builds on (most cited first, 25 of 25)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [ReAct: Synergizing Reasoning and Acting in Language Models](https://mlsanity.com/paper/2210.03629/) (2022)
- [Evaluating Large Language Models Trained on Code](https://mlsanity.com/paper/2107.03374/) (2021)
- [Program Synthesis with Large Language Models](https://mlsanity.com/paper/2108.07732/) (2021)
- [Pre-train, Prompt, and Predict: A Systematic Survey of Prompting Methods in Natural Language Processing](https://mlsanity.com/paper/2107.13586/) (2021)
- [Survey of Hallucination in Natural Language Generation](https://mlsanity.com/paper/2202.03629/) (2022)
- [A Survey on Hallucination in Large Language Models: Principles, Taxonomy, Challenges, and Open Questions](https://mlsanity.com/paper/2311.05232/) (2023)
- [Open Problems and Fundamental Limitations of Reinforcement Learning from Human Feedback](https://mlsanity.com/paper/2307.15217/) (2023)
- [Retrieval Augmentation Reduces Hallucination in Conversation](https://mlsanity.com/paper/2104.07567/) (2021)
- [A Prompt Pattern Catalog to Enhance Prompt Engineering with ChatGPT](https://mlsanity.com/paper/2302.11382/) (2023)
- [Decomposed Prompting: A Modular Approach for Solving Complex Tasks](https://mlsanity.com/paper/2210.02406/) (2022)
- [Large Language Models for Software Engineering: A Systematic Literature Review](https://mlsanity.com/paper/2308.10620/) (2023)
- [Hallucination is Inevitable: An Innate Limitation of Large Language Models](https://mlsanity.com/paper/2401.11817/) (2024)
- [Benchmark Data Contamination of Large Language Models: A Survey](https://mlsanity.com/paper/2406.04244/) (2024)
- [Seven Failure Points When Engineering a Retrieval Augmented Generation System](https://mlsanity.com/paper/2401.05856/) (2024)
- [Self-planning Code Generation with Large Language Models](https://mlsanity.com/paper/2303.06689/) (2023)
- [Evaluating the Code Quality of AI-Assisted Code Generation Tools: An Empirical Study on GitHub Copilot, Amazon CodeWhisperer, and ChatGPT](https://mlsanity.com/paper/2304.10778/) (2023)
- [What's Wrong with Your Code Generated by Large Language Models? An Extensive Study](https://mlsanity.com/paper/2407.06153/) (2024)
- [Fine-Tuning and Prompt Engineering for Large Language Models-based Code Review Automation](https://mlsanity.com/paper/2402.00905/) (2024)
- [GPT-Based Models Meet Simulation: How to Efficiently Use Large-Scale Pre-Trained Language Models Across Simulation Tasks](https://mlsanity.com/paper/2306.13679/) (2023)
- [Enhancing Computer Programming Education with LLMs: A Study on Effective Prompt Engineering for Python Code Generation](https://mlsanity.com/paper/2407.05437/) (2024)
- [Broadening Access to Simulations for End-Users via Large Language Models: Challenges and Opportunities](https://mlsanity.com/paper/2409.15290/) (2024)
- [Discrete-Event Simulation in Healthcare Settings: a Review](https://mlsanity.com/paper/2211.00061/) (2022)

## Built on by (most cited first, 2 of 2)

- [Generative Artificial Intelligence (GenAI) to convert images of queuing networks into verifiable simulation models: an open-weight LLM workflow approach](https://mlsanity.com/paper/2607.24259/) (2026)
- [Artificial Intelligence and Modeling & Simulation: An Overview](https://mlsanity.com/paper/2608.00366/) (2026)

## Abstract (arXiv)

Discrete-event simulation (DES) is widely used in healthcare Operations Research, but the models themselves are rarely shared. This limits their potential for reuse and long-term impact in the modelling and healthcare communities. This study explores the feasibility of using generative artificial intelligence (AI) to recreate published models using Free and Open Source Software (FOSS), based on the descriptions provided in an academic journal. Using a structured methodology, we successfully generated, tested and internally reproduced two DES models, including user interfaces. The reported results were replicated for one model, but not the other, likely due to missing information on distributions. These models are substantially more complex than AI-generated DES models published to date. Given the challenges we faced in prompt engineering, code generation, and model testing, we conclude that our iterative approach to model development, systematic comparison and testing, and the expertise of our team were necessary to the success of our recreated simulation models.
