# Injecting Adrenaline into LLM Serving: Boosting Resource Utilization and Throughput via Attention Disaggregation

arXiv: https://arxiv.org/abs/2503.20552 · HTML: https://mlsanity.com/paper/2503.20552/

## Key facts

- Cited by 14 papers in the map (data through 14 Oct 2026).
- Placed in Serving systems and request scheduling, one of 12 directions in Efficient LLM inference and serving.
- Builds on 13 of its 22 references that are in the map.
- First posted on arXiv 26 Mar 2025.

## Placed in

- Efficient LLM inference and serving / [Serving systems and request scheduling](https://mlsanity.com/inference/serving-systems-and-request-scheduling/)

## Builds on (most cited first, 13 of 13)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [Llama 2: Open Foundation and Fine-Tuned Chat Models](https://mlsanity.com/paper/2307.09288/) (2023)
- [Judging LLM-as-a-Judge with MT-Bench and Chatbot Arena](https://mlsanity.com/paper/2306.05685/) (2023)
- [Efficient Memory Management for Large Language Model Serving with PagedAttention](https://mlsanity.com/paper/2309.06180/) (2023)
- [Is Your Code Generated by ChatGPT Really Correct? Rigorous Evaluation of Large Language Models for Code Generation](https://mlsanity.com/paper/2305.01210/) (2023)
- [DistServe: Disaggregating Prefill and Decoding for Goodput-optimized Large Language Model Serving](https://mlsanity.com/paper/2401.09670/) (2024)
- [Splitwise: Efficient generative LLM inference using phase splitting](https://mlsanity.com/paper/2311.18677/) (2023)
- [Mooncake: A KVCache-centric Disaggregated Architecture for LLM Serving](https://mlsanity.com/paper/2407.00079/) (2024)
- [Cost-Efficient Large Language Model Serving for Multi-turn Conversations with CachedAttention](https://mlsanity.com/paper/2403.19708/) (2024)
- [FastDecode: High-Throughput GPU-Efficient LLM Serving using Heterogeneous Pipelines](https://mlsanity.com/paper/2403.11421/) (2024)
- [NEO: Saving GPU Memory Crisis with CPU Offloading for Online LLM Inference](https://mlsanity.com/paper/2411.01142/) (2024)
- [Efficient Heterogeneous Large Language Model Decoding with Model-Attention Disaggregation](https://mlsanity.com/paper/2405.01814/) (2024)

## Built on by (most cited first, 14 of 14)

- [Prefill-Decode Aggregation or Disaggregation? Unifying Both for Goodput-Optimized LLM Serving](https://mlsanity.com/paper/2508.01989/) (2025)
- [PDTrim: Targeted Pruning for Prefill-Decode Disaggregation in Inference](https://mlsanity.com/paper/2509.04467/) (2025)
- [DynaServe: Unified and Elastic Execution for Dynamic Disaggregated LLM Serving](https://mlsanity.com/paper/2504.09285/) (2025)
- [FairBatching: Fairness-Aware Batch Formation for LLM Inference](https://mlsanity.com/paper/2510.14392/) (2025)
- [Arrow: Adaptive Scheduling Mechanisms for Disaggregated LLM Inference Architecture](https://mlsanity.com/paper/2505.11916/) (2025)
- [Toward Cost-Efficient Serving of Mixture-of-Experts with Asynchrony](https://mlsanity.com/paper/2505.08944/) (2025)
- [Disaggregated Prefill and Decoding Inference System for Large Language Model Serving on Multi-Vendor GPUs](https://mlsanity.com/paper/2509.17542/) (2025)
- [RelayGR: Scaling Long-Sequence Generative Recommendation via Cross-Stage Relay-Race Inference](https://mlsanity.com/paper/2601.01712/) (2026)
- [Coordinated Scheduling for MoE LLM Serving](https://mlsanity.com/paper/2606.15177/) (2026)
- [Efficient MoE Inference with Fine-Grained Scheduling of Disaggregated Expert Parallelism](https://mlsanity.com/paper/2512.21487/) (2025)
- [Move the Query, Not the Cache: Characterizing Cross-Instance Latent Attention Redistribution Across GPU Fabrics](https://mlsanity.com/paper/2606.01502/) (2026)
- [Language Models Can Control Their Own Attention](https://mlsanity.com/paper/2609.02737/) (2026)
- [Q-First: Most of Attention Needs Only the Query in Disaggregated LLM Decoding](https://mlsanity.com/paper/2608.15473/) (2026)
- [LLM Inference on IMC-NoC Architecture with Balanced Dataflow and Fine-Grained Parallelism](https://mlsanity.com/paper/2609.00857/) (2026)

## Abstract (arXiv)

In large language model (LLM) serving systems, executing each request consists of two phases: the compute-intensive prefill phase and the memory-intensive decoding phase. To prevent performance interference between the two phases, current LLM serving systems typically adopt prefill-decoding disaggregation, where the two phases are split across separate machines. However, we observe this approach leads to significant resource underutilization. Specifically, prefill instances that are compute-intensive suffer from low memory utilization, while decoding instances that are memory-intensive experience low compute utilization. To address this problem, this paper proposes Adrenaline, an attention disaggregation and offloading mechanism designed to enhance resource utilization and performance in LLM serving systems. Adrenaline's key innovation lies in disaggregating part of the attention computation in the decoding phase and offloading them to prefill instances. The memory-bound nature of decoding-phase attention computation inherently enables an effective offloading strategy, yielding two complementary advantages: 1) improved memory capacity and bandwidth utilization in prefill instances, and 2) increased decoding batch sizes that enhance compute utilization in decoding instances, collectively boosting overall system performance. Adrenaline achieves these gains through three key techniques: low-latency decoding synchronization, resource-efficient prefill colocation, and load-aware offloading scheduling. Experimental results show that Adrenaline achieves 2.28x higher memory capacity and 2.07x better memory bandwidth utilization in prefill instances, up to 1.67x improvements in compute utilization for decoding instances, and 1.68x higher overall inference throughput compared to state-of-the-art systems.