# Optimizing Breast Cancer Detection in Mammograms: A Comprehensive Study of Transfer Learning, Resolution Reduction, and Multi-View Classification

arXiv: https://arxiv.org/abs/2503.19945 · HTML: https://mlsanity.com/paper/2503.19945/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 15 of its 41 references that are in the map.
- First posted on arXiv 25 Mar 2025.

## Builds on (most cited first, 15 of 15)

- [A ConvNet for the 2020s](https://mlsanity.com/paper/2201.03545/) (2022)
- [Bag of Tricks for Image Classification with Convolutional Neural Networks](https://mlsanity.com/paper/1812.01187/) (2018)
- [ResNet strikes back: An improved training procedure in timm](https://mlsanity.com/paper/2110.00476/) (2021)
- [Deep Neural Networks Improve Radiologists' Performance in Breast Cancer Screening](https://mlsanity.com/paper/1903.08297/) (2019)
- [End-to-end Training for Whole Image Breast Cancer Diagnosis using An All Convolutional Design](https://mlsanity.com/paper/1711.05775/) (2017)
- [Battle of the Backbones: A Large-Scale Comparison of Pretrained Models across Computer Vision Tasks](https://mlsanity.com/paper/2310.19909/) (2023)
- [Learning to Resize Images for Computer Vision Tasks](https://mlsanity.com/paper/2103.09950/) (2021)
- [Breast Cancer Diagnosis in Two-View Mammography Using End-to-End Trained EfficientNet-Based Convolutional Network](https://mlsanity.com/paper/2110.01606/) (2021)
- [Multi-view Local Co-occurrence and Global Consistency Learning Improve Mammogram Classification Generalisation](https://mlsanity.com/paper/2209.10478/) (2022)
- [MV-Swin-T: Mammogram Classification with Multi-view Swin Transformer](https://mlsanity.com/paper/2402.16298/) (2024)
- [Towards Robust Natural-Looking Mammography Lesion Synthesis on Ipsilateral Dual-Views Breast Cancer Analysis](https://mlsanity.com/paper/2309.03506/) (2023)
- [CSAW-M: An Ordinal Classification Dataset for Benchmarking Mammographic Masking of Cancer](https://mlsanity.com/paper/2112.01330/) (2021)
- [Beyond Fine-tuning: Classifying High Resolution Mammograms using Function-Preserving Transformations](https://mlsanity.com/paper/2101.07945/) (2021)
- [Full Field Digital Mammography Dataset from a Population Screening Program](https://mlsanity.com/paper/2411.02710/) (2024)
- [The EMory BrEast imaging Dataset (EMBED): A Racially Diverse, Granular Dataset of 3.5M Screening and Diagnostic Mammograms](https://mlsanity.com/paper/2202.04073/) (2022)

## Built on by (most cited first, 1 of 1)

- [AEGIS: A Multi-Task Joint-Embedding Predictive Architecture for Mammography](https://mlsanity.com/paper/2607.00277/) (2026)

## Abstract (arXiv)

Mammography, an X-ray-based imaging technique, remains central to the early detection of breast cancer. Recent advances in artificial intelligence have enabled increasingly sophisticated computer-aided diagnostic methods, evolving from patch-based classifiers to whole-image approaches and then to multi-view architectures that jointly analyze complementary projections. Despite this progress, several critical questions remain unanswered. In this study, we systematically investigate these issues by addressing five key research questions: (1) the role of patch classifiers in performance, (2) the transferability of natural-image-trained backbones, (3) the advantages of learn-to-resize over conventional downscaling, (4) the contribution of multi-view integration, and (5) the robustness of findings across varying image quality. Beyond benchmarking, our experiments demonstrate clear performance gains over prior work. For the CBIS-DDSM dataset, we improved single-view AUC from 0.8153 to 0.8343, and multiple-view AUC from 0.8483 to 0.8658. Using a new comparative method, we also observed a 0.0217 AUC increase when extending from single to multiple-view analysis. On the complete VinDr-Mammo dataset, the multiple-view approach further improved results, achieving a 0.0492 AUC increase over single view and reaching 0.8511 AUC overall. These results establish new state-of-the-art benchmarks, providing clear evidence of the advantages of multi-view architectures for mammogram interpretation. Beyond performance, our analysis offers principled insights into model design and transfer learning strategies, contributing to the development of more accurate and reliable breast cancer screening tools. The inference code and trained models are publicly available at https://github.com/dpetrini/multiple-view.
